These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 26240024)

  • 1. The ubiquitin ligase RNF43 downregulation increases membrane expression of frizzled receptor in pancreatic ductal adenocarcinoma.
    Wang D; Tan J; Xu Y; Han M; Tu Y; Zhu Z; Dou C; Xin J; Tan X; Zeng JP; Zhao G; Liu Z
    Tumour Biol; 2016 Jan; 37(1):627-31. PubMed ID: 26240024
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inactivating mutations of RNF43 confer Wnt dependency in pancreatic ductal adenocarcinoma.
    Jiang X; Hao HX; Growney JD; Woolfenden S; Bottiglio C; Ng N; Lu B; Hsieh MH; Bagdasarian L; Meyer R; Smith TR; Avello M; Charlat O; Xie Y; Porter JA; Pan S; Liu J; McLaughlin ME; Cong F
    Proc Natl Acad Sci U S A; 2013 Jul; 110(31):12649-54. PubMed ID: 23847203
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors.
    Steinhart Z; Pavlovic Z; Chandrashekhar M; Hart T; Wang X; Zhang X; Robitaille M; Brown KR; Jaksani S; Overmeer R; Boj SF; Adams J; Pan J; Clevers H; Sidhu S; Moffat J; Angers S
    Nat Med; 2017 Jan; 23(1):60-68. PubMed ID: 27869803
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Rnf43.
    Serra S; Chetty R
    J Clin Pathol; 2018 Jan; 71(1):1-6. PubMed ID: 29018044
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Krüppel-like factor 9 suppressed tumorigenicity of the pancreatic ductal adenocarcinoma by negatively regulating frizzled-5.
    Ji P; Fan X; Ma X; Wang X; Zhang J; Mao Z
    Biochem Biophys Res Commun; 2018 May; 499(4):815-821. PubMed ID: 29621541
    [TBL] [Abstract][Full Text] [Related]  

  • 6. RNF43 R117fs mutant positively regulates Wnt/β-catenin signaling by failing to internalize FZD expressed on the cell surface.
    Cho AR; Sul HJ; Kim YJ; Kim B; Zang DY
    Sci Rep; 2022 Apr; 12(1):7013. PubMed ID: 35487932
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Clinicopathological significance of somatic RNF43 mutation and aberrant expression of ring finger protein 43 in intraductal papillary mucinous neoplasms of the pancreas.
    Sakamoto H; Kuboki Y; Hatori T; Yamamoto M; Sugiyama M; Shibata N; Shimizu K; Shiratori K; Furukawa T
    Mod Pathol; 2015 Feb; 28(2):261-7. PubMed ID: 25081753
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors.
    Koo BK; Spit M; Jordens I; Low TY; Stange DE; van de Wetering M; van Es JH; Mohammed S; Heck AJ; Maurice MM; Clevers H
    Nature; 2012 Aug; 488(7413):665-9. PubMed ID: 22895187
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The E3 ligase RNF43 inhibits Wnt signaling downstream of mutated β-catenin by sequestering TCF4 to the nuclear membrane.
    Loregger A; Grandl M; Mejías-Luque R; Allgäuer M; Degenhart K; Haselmann V; Oikonomou C; Hatzis P; Janssen KP; Nitsche U; Gradl D; van den Broek O; Destree O; Ulm K; Neumaier M; Kalali B; Jung A; Varela I; Schmid RM; Rad R; Busch DH; Gerhard M
    Sci Signal; 2015 Sep; 8(393):ra90. PubMed ID: 26350900
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Molecular Role of RNF43 in Canonical and Noncanonical Wnt Signaling.
    Tsukiyama T; Fukui A; Terai S; Fujioka Y; Shinada K; Takahashi H; Yamaguchi TP; Ohba Y; Hatakeyama S
    Mol Cell Biol; 2015 Jun; 35(11):2007-23. PubMed ID: 25825523
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dishevelled promotes Wnt receptor degradation through recruitment of ZNRF3/RNF43 E3 ubiquitin ligases.
    Jiang X; Charlat O; Zamponi R; Yang Y; Cong F
    Mol Cell; 2015 May; 58(3):522-33. PubMed ID: 25891077
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ring finger protein 43 associates with gastric cancer progression and attenuates the stemness of gastric cancer stem-like cells via the Wnt-β/catenin signaling pathway.
    Gao Y; Cai A; Xi H; Li J; Xu W; Zhang Y; Zhang K; Cui J; Wu X; Wei B; Chen L
    Stem Cell Res Ther; 2017 Apr; 8(1):98. PubMed ID: 28446252
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Deficient Rnf43 potentiates hyperactive Kras-mediated pancreatic preneoplasia initiation and malignant transformation.
    Zhou X; Sun Z; Zhang M; Qu X; Yang S; Wang L; Jing Y; Li L; Deng W; Liu F; Di J; Chen J; Wu J; Zhang H
    Animal Model Exp Med; 2022 Feb; 5(1):61-71. PubMed ID: 35229994
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Loss of Rnf43 Accelerates Kras-Mediated Neoplasia and Remodels the Tumor Immune Microenvironment in Pancreatic Adenocarcinoma.
    Hosein AN; Dangol G; Okumura T; Roszik J; Rajapakshe K; Siemann M; Zaid M; Ghosh B; Monberg M; Guerrero PA; Singhi A; Haymaker CL; Clevers H; Abou-Elkacem L; Woermann SM; Maitra A
    Gastroenterology; 2022 Apr; 162(4):1303-1318.e18. PubMed ID: 34973294
    [TBL] [Abstract][Full Text] [Related]  

  • 15. UBL4A inhibits autophagy-mediated proliferation and metastasis of pancreatic ductal adenocarcinoma via targeting LAMP1.
    Chen H; Li L; Hu J; Zhao Z; Ji L; Cheng C; Zhang G; Zhang T; Li Y; Chen H; Pan S; Sun B
    J Exp Clin Cancer Res; 2019 Jul; 38(1):297. PubMed ID: 31288830
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PROX1 and β-catenin are prognostic markers in pancreatic ductal adenocarcinoma.
    Saukkonen K; Hagström J; Mustonen H; Juuti A; Nordling S; Kallio P; Alitalo K; Seppänen H; Haglund C
    BMC Cancer; 2016 Jul; 16():472. PubMed ID: 27411302
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DEK protein overexpression predicts poor prognosis in pancreatic ductal adenocarcinoma.
    Sun J; Bi F; Yang Y; Zhang Y; Jin A; Li J; Lin Z
    Oncol Rep; 2017 Feb; 37(2):857-864. PubMed ID: 27959420
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Lunatic Fringe is a potent tumor suppressor in Kras-initiated pancreatic cancer.
    Zhang S; Chung WC; Xu K
    Oncogene; 2016 May; 35(19):2485-95. PubMed ID: 26279302
    [TBL] [Abstract][Full Text] [Related]  

  • 19. β2-adrenergic receptor signaling promotes pancreatic ductal adenocarcinoma (PDAC) progression through facilitating PCBP2-dependent c-myc expression.
    Wan C; Gong C; Zhang H; Hua L; Li X; Chen X; Chen Y; Ding X; He S; Cao W; Wang Y; Fan S; Xiao Y; Zhou G; Shen A
    Cancer Lett; 2016 Apr; 373(1):67-76. PubMed ID: 26803058
    [TBL] [Abstract][Full Text] [Related]  

  • 20. (Pro)renin receptor is crucial for Wnt/β-catenin-dependent genesis of pancreatic ductal adenocarcinoma.
    Shibayama Y; Fujimori T; Nguyen G; Hirose T; Totsune K; Ichihara A; Kitada K; Nakano D; Kobori H; Kohno M; Masaki T; Suzuki Y; Yachida S; Nishiyama A
    Sci Rep; 2015 Mar; 5():8854. PubMed ID: 25747895
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.