These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

363 related articles for article (PubMed ID: 26240069)

  • 1. Reversal of the Drug Binding Pocket Defects of the AcrB Multidrug Efflux Pump Protein of Escherichia coli.
    Soparkar K; Kinana AD; Weeks JW; Morrison KD; Nikaido H; Misra R
    J Bacteriol; 2015 Oct; 197(20):3255-64. PubMed ID: 26240069
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives.
    Sjuts H; Vargiu AV; Kwasny SM; Nguyen ST; Kim HS; Ding X; Ornik AR; Ruggerone P; Bowlin TL; Nikaido H; Pos KM; Opperman TJ
    Proc Natl Acad Sci U S A; 2016 Mar; 113(13):3509-14. PubMed ID: 26976576
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Site-directed mutagenesis reveals putative substrate binding residues in the Escherichia coli RND efflux pump AcrB.
    Bohnert JA; Schuster S; Seeger MA; Fähnrich E; Pos KM; Kern WV
    J Bacteriol; 2008 Dec; 190(24):8225-9. PubMed ID: 18849422
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Kinetic analysis of the inhibition of the drug efflux protein AcrB using surface plasmon resonance.
    Mowla R; Wang Y; Ma S; Venter H
    Biochim Biophys Acta Biomembr; 2018 Apr; 1860(4):878-886. PubMed ID: 28890187
    [TBL] [Abstract][Full Text] [Related]  

  • 5. AcrB-AcrA Fusion Proteins That Act as Multidrug Efflux Transporters.
    Hayashi K; Nakashima R; Sakurai K; Kitagawa K; Yamasaki S; Nishino K; Yamaguchi A
    J Bacteriol; 2016 Jan; 198(2):332-42. PubMed ID: 26527645
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effect of the F610A mutation on substrate extrusion in the AcrB transporter: explanation and rationale by molecular dynamics simulations.
    Vargiu AV; Collu F; Schulz R; Pos KM; Zacharias M; Kleinekathöfer U; Ruggerone P
    J Am Chem Soc; 2011 Jul; 133(28):10704-7. PubMed ID: 21707050
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Genetic evidence for functional interactions between TolC and AcrA proteins of a major antibiotic efflux pump of Escherichia coli.
    Gerken H; Misra R
    Mol Microbiol; 2004 Nov; 54(3):620-31. PubMed ID: 15491355
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Chlorpromazine and Amitriptyline Are Substrates and Inhibitors of the AcrB Multidrug Efflux Pump.
    Grimsey EM; Fais C; Marshall RL; Ricci V; Ciusa ML; Stone JW; Ivens A; Malloci G; Ruggerone P; Vargiu AV; Piddock LJV
    mBio; 2020 Jun; 11(3):. PubMed ID: 32487753
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Some ligands enhance the efflux of other ligands by the Escherichia coli multidrug pump AcrB.
    Kinana AD; Vargiu AV; Nikaido H
    Biochemistry; 2013 Nov; 52(46):8342-51. PubMed ID: 24205856
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Metabolomics Reveal Potential Natural Substrates of AcrB in Escherichia coli and Salmonella enterica Serovar Typhimurium.
    Wang-Kan X; Rodríguez-Blanco G; Southam AD; Winder CL; Dunn WB; Ivens A; Piddock LJV
    mBio; 2021 Mar; 12(2):. PubMed ID: 33785633
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effect of site-directed mutations in multidrug efflux pump AcrB examined by quantitative efflux assays.
    Kinana AD; Vargiu AV; Nikaido H
    Biochem Biophys Res Commun; 2016 Nov; 480(4):552-557. PubMed ID: 27789287
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The AcrB efflux pump: conformational cycling and peristalsis lead to multidrug resistance.
    Seeger MA; Diederichs K; Eicher T; Brandstätter L; Schiefner A; Verrey F; Pos KM
    Curr Drug Targets; 2008 Sep; 9(9):729-49. PubMed ID: 18781920
    [TBL] [Abstract][Full Text] [Related]  

  • 13. AcrB drug-binding pocket substitution confers clinically relevant resistance and altered substrate specificity.
    Blair JM; Bavro VN; Ricci V; Modi N; Cacciotto P; Kleinekathӧfer U; Ruggerone P; Vargiu AV; Baylay AJ; Smith HE; Brandon Y; Galloway D; Piddock LJ
    Proc Natl Acad Sci U S A; 2015 Mar; 112(11):3511-6. PubMed ID: 25737552
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Evaluation of a series of 2-napthamide derivatives as inhibitors of the drug efflux pump AcrB for the reversal of antimicrobial resistance.
    Wang Y; Mowla R; Guo L; Ogunniyi AD; Rahman T; De Barros Lopes MA; Ma S; Venter H
    Bioorg Med Chem Lett; 2017 Feb; 27(4):733-739. PubMed ID: 28129976
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Interactions underlying assembly of the Escherichia coli AcrAB-TolC multidrug efflux system.
    Touzé T; Eswaran J; Bokma E; Koronakis E; Hughes C; Koronakis V
    Mol Microbiol; 2004 Jul; 53(2):697-706. PubMed ID: 15228545
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Random mutagenesis of the multidrug transporter AcrB from Escherichia coli for identification of putative target residues of efflux pump inhibitors.
    Schuster S; Kohler S; Buck A; Dambacher C; König A; Bohnert JA; Kern WV
    Antimicrob Agents Chemother; 2014 Nov; 58(11):6870-8. PubMed ID: 25182653
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Unidirectional peristaltic movement in multisite drug binding pockets of AcrB from molecular dynamics simulations.
    Feng Z; Hou T; Li Y
    Mol Biosyst; 2012 Oct; 8(10):2699-709. PubMed ID: 22825052
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Single nucleotide polymorphism analysis of the major tripartite multidrug efflux pump of Escherichia coli: functional conservation in disparate animal reservoirs despite exposure to antimicrobial chemotherapy.
    Elkins CA; Mullis LB; Lacher DW; Jung CM
    Antimicrob Agents Chemother; 2010 Mar; 54(3):1007-15. PubMed ID: 20038628
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Evidence of a Substrate-Discriminating Entrance Channel in the Lower Porter Domain of the Multidrug Resistance Efflux Pump AcrB.
    Schuster S; Vavra M; Kern WV
    Antimicrob Agents Chemother; 2016 Jul; 60(7):4315-23. PubMed ID: 27161641
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The C-terminal domain of AcrA is essential for the assembly and function of the multidrug efflux pump AcrAB-TolC.
    Ge Q; Yamada Y; Zgurskaya H
    J Bacteriol; 2009 Jul; 191(13):4365-71. PubMed ID: 19411330
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.