273 related articles for article (PubMed ID: 26242737)
1. Dihydrofolate Reductase and Thymidylate Synthase Transgenes Resistant to Methotrexate Interact to Permit Novel Transgene Regulation.
Rushworth D; Mathews A; Alpert A; Cooper LJ
J Biol Chem; 2015 Sep; 290(38):22970-6. PubMed ID: 26242737
[TBL] [Abstract][Full Text] [Related]
2. Antithymidylate resistance enables transgene selection and cell survival for T cells in the presence of 5-fluorouracil and antifolates.
Rushworth D; Alpert A; Santana-Carrero R; Olivares S; Spencer D; Cooper LJ
Gene Ther; 2016 Feb; 23(2):119-28. PubMed ID: 26273805
[TBL] [Abstract][Full Text] [Related]
3. Alterations in the expression pattern of MTHFR, DHFR, TYMS, and SLC19A1 genes after treatment of laryngeal cancer cells with high and low doses of methotrexate.
Galbiatti AL; Castro R; Caldas HC; Padovani JA; Pavarino EC; Goloni-Bertollo EM
Tumour Biol; 2013 Dec; 34(6):3765-71. PubMed ID: 23838799
[TBL] [Abstract][Full Text] [Related]
4. Retroviral transduction of a mutant dihydrofolate reductase-thymidylate synthase fusion gene into murine marrow cells confers resistance to both methotrexate and 5-fluorouracil.
Capiaux GM; Budak-Alpdogan T; Takebe N; Mayer-Kuckuk P; Banerjee D; Maley F; Bertino JR
Hum Gene Ther; 2003 Mar; 14(5):435-46. PubMed ID: 12691609
[TBL] [Abstract][Full Text] [Related]
5. Human dihydrofolate reductase and thymidylate synthase form a complex in vitro and co-localize in normal and cancer cells.
Antosiewicz A; Jarmuła A; Przybylska D; Mosieniak G; Szczepanowska J; Kowalkowska A; Rode W; Cieśla J
J Biomol Struct Dyn; 2017 May; 35(7):1474-1490. PubMed ID: 27187663
[TBL] [Abstract][Full Text] [Related]
6. Novel aspects of resistance to drugs targeted to dihydrofolate reductase and thymidylate synthase.
Banerjee D; Mayer-Kuckuk P; Capiaux G; Budak-Alpdogan T; Gorlick R; Bertino JR
Biochim Biophys Acta; 2002 Jul; 1587(2-3):164-73. PubMed ID: 12084458
[TBL] [Abstract][Full Text] [Related]
7. Isolation and characterization of a mutant dihydrofolate reductase-thymidylate synthase from methotrexate-resistant Leishmania cells.
Arrebola R; Olmo A; Reche P; Garvey EP; Santi DV; Ruiz-Perez LM; Gonzalez-Pacanowska D
J Biol Chem; 1994 Apr; 269(14):10590-6. PubMed ID: 8144647
[TBL] [Abstract][Full Text] [Related]
8. Molecular mechanism of chemoresistance by miR-215 in osteosarcoma and colon cancer cells.
Song B; Wang Y; Titmus MA; Botchkina G; Formentini A; Kornmann M; Ju J
Mol Cancer; 2010 Apr; 9():96. PubMed ID: 20433742
[TBL] [Abstract][Full Text] [Related]
9. Combined gene deletion of dihydrofolate reductase-thymidylate synthase and pteridine reductase in Leishmania infantum.
Bhattacharya A; Leprohon P; Ouellette M
PLoS Negl Trop Dis; 2021 Apr; 15(4):e0009377. PubMed ID: 33905412
[TBL] [Abstract][Full Text] [Related]
10. Maintenance of differential methotrexate toxicity between cells expressing drug-resistant and wild-type dihydrofolate reductase activities in the presence of nucleosides through nucleoside transport inhibition.
Warlick CA; Sweeney CL; McIvor RS
Biochem Pharmacol; 2000 Jan; 59(2):141-51. PubMed ID: 10810448
[TBL] [Abstract][Full Text] [Related]
11. Analysis of dihydrofolate reductase and reduced folate carrier gene status in relation to methotrexate resistance in osteosarcoma cells.
Serra M; Reverter-Branchat G; Maurici D; Benini S; Shen JN; Chano T; Hattinger CM; Manara MC; Pasello M; Scotlandi K; Picci P
Ann Oncol; 2004 Jan; 15(1):151-60. PubMed ID: 14679136
[TBL] [Abstract][Full Text] [Related]
12. Dihydrofolate reductase transcript level is not suitable for methotrexate-resistance prediction in choriocarcinoma cell line.
Han B; Xiang Y; Wang Y; Wang Z; Zhang H; Huang S
Int J Gynecol Cancer; 2010 Oct; 20(7):1259-63. PubMed ID: 21495249
[TBL] [Abstract][Full Text] [Related]
13. In vivo protection of activated Tyr22-dihydrofolate reductase gene-modified canine T lymphocytes from methotrexate.
Gori JL; Beard BC; Williams NP; Ironside C; Swanson D; Scott McIvor R; Kiem HP
J Gene Med; 2013; 15(6-7):233-41. PubMed ID: 23666780
[TBL] [Abstract][Full Text] [Related]
14. Drug-resistant dihydrofolate reductases: generation, expression and therapeutic application.
McIvor RS
Bone Marrow Transplant; 1996 Dec; 18 Suppl 3():S50-4. PubMed ID: 8971409
[TBL] [Abstract][Full Text] [Related]
15. Prognostic significance of numeric aberrations of genes for thymidylate synthase, thymidine phosphorylase and dihydrofolate reductase in colorectal cancer.
Jensen SA; Vainer B; Witton CJ; Jørgensen JT; Sørensen JB
Acta Oncol; 2008; 47(6):1054-61. PubMed ID: 18607850
[TBL] [Abstract][Full Text] [Related]
16. Role of the locus and of the resistance gene on gene amplification frequency in methotrexate resistant Leishmania tarentolae.
Kündig C; Leblanc E; Papadopoulou B; Ouellette M
Nucleic Acids Res; 1999 Sep; 27(18):3653-9. PubMed ID: 10471733
[TBL] [Abstract][Full Text] [Related]
17. Generation of dual resistance to 4-hydroperoxycyclophosphamide and methotrexate by retroviral transfer of the human aldehyde dehydrogenase class 1 gene and a mutated dihydrofolate reductase gene.
Takebe N; Zhao SC; Adhikari D; Mineishi S; Sadelain M; Hilton J; Colvin M; Banerjee D; Bertino JR
Mol Ther; 2001 Jan; 3(1):88-96. PubMed ID: 11162315
[TBL] [Abstract][Full Text] [Related]
18. Large diversity in transport-mediated methotrexate resistance in human leukemia cell line CCRF-CEM established in a high concentration of leucovorin.
Asai S; Miyachi H; Kobayashi H; Takemura Y; Ando Y
Cancer Sci; 2003 Feb; 94(2):210-4. PubMed ID: 12708499
[TBL] [Abstract][Full Text] [Related]
19. The influence of drug-exposure conditions on the development of resistance to methotrexate or ZD1694 in cultured human leukaemia cells.
Takemura Y; Kobayashi H; Gibson W; Kimbell R; Miyachi H; Jackman AL
Int J Cancer; 1996 Mar; 66(1):29-36. PubMed ID: 8608962
[TBL] [Abstract][Full Text] [Related]
20. [Primary study on establishment of namalwa 12/MTX resistant cell strain and its mechanism].
Chen J; Gu LJ; Ying DM; Shen M; Wu HJ
Ai Zheng; 2002 Dec; 21(12):1335-40. PubMed ID: 12520743
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
