BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

154 related articles for article (PubMed ID: 26243370)

  • 1. Design, synthesis and RON receptor tyrosine kinase inhibitory activity of new head groups analogs of LCRF-0004.
    Raeppel F; Raeppel SL; Therrien E
    Bioorg Med Chem Lett; 2015 Sep; 25(18):3810-5. PubMed ID: 26243370
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design and synthesis of close analogs of LCRF-0004, a potent and selective RON receptor tyrosine kinase inhibitor.
    Raeppel SL; Raeppel F; Therrien E
    Bioorg Med Chem Lett; 2015 Jun; 25(12):2527-31. PubMed ID: 25953155
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design and synthesis of constrained analogs of LCRF-0004 as potent RON tyrosine kinase inhibitors.
    Raeppel SL; Therrien E; Raeppel F
    Bioorg Med Chem Lett; 2015 Sep; 25(17):3706-10. PubMed ID: 26112445
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of a novel series of potent RON receptor tyrosine kinase inhibitors.
    Raeppel S; Gaudette F; Mannion M; Claridge S; Saavedra O; Isakovic L; Déziel R; Beaulieu N; Beaulieu C; Dupont I; Nguyen H; Wang J; Macleod AR; Maroun C; Besterman JM; Vaisburg A
    Bioorg Med Chem Lett; 2010 May; 20(9):2745-9. PubMed ID: 20363625
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and biological evaluation of 5-substituted 1,4-dihydroindeno[1,2-c]pyrazoles as multitargeted receptor tyrosine kinase inhibitors.
    Akritopoulou-Zanze I; Albert DH; Bousquet PF; Cunha GA; Harris CM; Moskey M; Dinges J; Stewart KD; Sowin TJ
    Bioorg Med Chem Lett; 2007 Jun; 17(11):3136-40. PubMed ID: 17391959
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and biological evaluation of new pyrazol-4-ylpyrimidine derivatives as potential ROS1 kinase inhibitors.
    Abdelazem AZ; Al-Sanea MM; Park BS; Park HM; Yoo KH; Sim T; Park JB; Lee SH; Lee SH
    Eur J Med Chem; 2015 Jan; 90():195-208. PubMed ID: 25461320
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Identification of a novel recepteur d'origine nantais/c-met small-molecule kinase inhibitor with antitumor activity in vivo.
    Zhang Y; Kaplan-Lefko PJ; Rex K; Yang Y; Moriguchi J; Osgood T; Mattson B; Coxon A; Reese M; Kim TS; Lin J; Chen A; Burgess TL; Dussault I
    Cancer Res; 2008 Aug; 68(16):6680-7. PubMed ID: 18701492
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Imidazo[1,2-a]pyridin-6-yl-benzamide analogs as potent RAF inhibitors.
    Smith A; Ni ZJ; Poon D; Huang Z; Chen Z; Zhang Q; Tandeske L; Merritt H; Shoemaker K; Chan J; Kaufman S; Huh K; Murray J; Appleton BA; Cowan-Jacob SW; Scheufler C; Kanazawa T; Jansen JM; Stuart D; Shafer CM
    Bioorg Med Chem Lett; 2017 Dec; 27(23):5221-5224. PubMed ID: 29107542
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design and synthesis of novel 3-sulfonylpyrazol-4-amino pyrimidines as potent anaplastic lymphoma kinase (ALK) inhibitors.
    Zhang P; Dong J; Zhong B; Zhang D; Yuan H; Jin C; Xu X; Li H; Zhou Y; Liang Z; Ji M; Xu T; Song G; Zhang L; Chen G; Meng X; Sun D; Shih J; Zhang R; Hou G; Wang C; Jin Y; Yang Q
    Bioorg Med Chem Lett; 2016 Apr; 26(8):1910-8. PubMed ID: 26979157
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis, Docking Study and Kinase Inhibitory Activity of a Number of New Substituted Pyrazolo[3,4-c]pyridines.
    Sklepari M; Lougiakis N; Papastathopoulos A; Pouli N; Marakos P; Myrianthopoulos V; Robert T; Bach S; Mikros E; Ruchaud S
    Chem Pharm Bull (Tokyo); 2017; 65(1):66-81. PubMed ID: 28049917
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 7-Aminopyrazolo[1,5-a]pyrimidines as potent multitargeted receptor tyrosine kinase inhibitors.
    Frey RR; Curtin ML; Albert DH; Glaser KB; Pease LJ; Soni NB; Bouska JJ; Reuter D; Stewart KD; Marcotte P; Bukofzer G; Li J; Davidsen SK; Michaelides MR
    J Med Chem; 2008 Jul; 51(13):3777-87. PubMed ID: 18557606
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure-based design, synthesis, and evaluation of imidazo[1,2-b]pyridazine and imidazo[1,2-a]pyridine derivatives as novel dual c-Met and VEGFR2 kinase inhibitors.
    Matsumoto S; Miyamoto N; Hirayama T; Oki H; Okada K; Tawada M; Iwata H; Nakamura K; Yamasaki S; Miki H; Hori A; Imamura S
    Bioorg Med Chem; 2013 Dec; 21(24):7686-98. PubMed ID: 24216091
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure-based design, synthesis, and evaluation of 4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine derivatives as novel c-Met inhibitors.
    Zhang L; Zhang B; Zhao J; Zhi Y; Wang L; Lu T; Chen Y
    Eur J Med Chem; 2017 Sep; 138():942-951. PubMed ID: 28755635
    [TBL] [Abstract][Full Text] [Related]  

  • 14. ALK5 kinase inhibitory activity and synthesis of 2,3,4-substituted 5,5-dimethyl-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazoles.
    Řezníčková E; Tenora L; Pospíšilová P; Galeta J; Jorda R; Berka K; Majer P; Potáček M; Kryštof V
    Eur J Med Chem; 2017 Feb; 127():632-642. PubMed ID: 28135685
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis and biological evaluation of 1H-pyrrolo[2,3-b]pyridine and 1H-pyrazolo[3,4-b]pyridine derivatives as c-Met inhibitors.
    Liu N; Wang Y; Huang G; Ji C; Fan W; Li H; Cheng Y; Tian H
    Bioorg Chem; 2016 Apr; 65():146-58. PubMed ID: 26950400
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Inhibitors of the TAM subfamily of tyrosine kinases: synthesis and biological evaluation.
    Suárez RM; Chevot F; Cavagnino A; Saettel N; Radvanyi F; Piguel S; Bernard-Pierrot I; Stoven V; Legraverend M
    Eur J Med Chem; 2013 Mar; 61():2-25. PubMed ID: 22749189
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Scaffold oriented synthesis. Part 2: Design, synthesis and biological evaluation of pyrimido-diazepines as receptor tyrosine kinase inhibitors.
    Gracias V; Ji Z; Akritopoulou-Zanze I; Abad-Zapatero C; Huth JR; Song D; Hajduk PJ; Johnson EF; Glaser KB; Marcotte PA; Pease L; Soni NB; Stewart KD; Davidsen SK; Michaelides MR; Djuric SW
    Bioorg Med Chem Lett; 2008 Apr; 18(8):2691-5. PubMed ID: 18362070
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pyrazolo[1,5-a]pyrimidine based Trk inhibitors: Design, synthesis, biological activity evaluation.
    Zhang Y; Liu Y; Zhou Y; Zhang Q; Han T; Tang C; Fan W
    Bioorg Med Chem Lett; 2021 Jan; 31():127712. PubMed ID: 33246108
    [TBL] [Abstract][Full Text] [Related]  

  • 19. New aminopyrimidine derivatives as inhibitors of the TAM family.
    Traoré T; Cavagnino A; Saettel N; Radvanyi F; Piguel S; Bernard-Pierrot I; Stoven V; Legraverend M
    Eur J Med Chem; 2013; 70():789-801. PubMed ID: 24239626
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Kinase domain inhibition of leucine rich repeat kinase 2 (LRRK2) using a [1,2,4]triazolo[4,3-b]pyridazine scaffold.
    Galatsis P; Henderson JL; Kormos BL; Han S; Kurumbail RG; Wager TT; Verhoest PR; Noell GS; Chen Y; Needle E; Berger Z; Steyn SJ; Houle C; Hirst WD
    Bioorg Med Chem Lett; 2014 Sep; 24(17):4132-40. PubMed ID: 25113930
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.