These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

711 related articles for article (PubMed ID: 26243569)

  • 1. A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome.
    Wiseman FK; Al-Janabi T; Hardy J; Karmiloff-Smith A; Nizetic D; Tybulewicz VL; Fisher EM; Strydom A
    Nat Rev Neurosci; 2015 Sep; 16(9):564-74. PubMed ID: 26243569
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Genetic Mapping of APP and Amyloid-β Biology Modulation by Trisomy 21.
    Mumford P; Tosh J; Anderle S; Gkanatsiou Wikberg E; Lau G; Noy S; Cleverley K; Saito T; Saido TC; Yu E; Brinkmalm G; Portelius E; Blennow K; Zetterberg H; Tybulewicz V; Fisher EMC; Wiseman FK
    J Neurosci; 2022 Aug; 42(33):6453-6468. PubMed ID: 35835549
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Genetic dissection of down syndrome-associated alterations in APP/amyloid-β biology using mouse models.
    Tosh JL; Rhymes ER; Mumford P; Whittaker HT; Pulford LJ; Noy SJ; Cleverley K; ; Walker MC; Tybulewicz VLJ; Wykes RC; Fisher EMC; Wiseman FK
    Sci Rep; 2021 Mar; 11(1):5736. PubMed ID: 33707583
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Genetic susceptibility to Alzheimer disease.
    Pericak-Vance MA; Haines JL
    Trends Genet; 1995 Dec; 11(12):504-8. PubMed ID: 8533168
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Comparison of CSF biomarkers in Down syndrome and autosomal dominant Alzheimer's disease: a cross-sectional study.
    Fagan AM; Henson RL; Li Y; Boerwinkle AH; Xiong C; Bateman RJ; Goate A; Ances BM; Doran E; Christian BT; Lai F; Rosas HD; Schupf N; Krinsky-McHale S; Silverman W; Lee JH; Klunk WE; Handen BL; Allegri RF; Chhatwal JP; Day GS; Graff-Radford NR; Jucker M; Levin J; Martins RN; Masters CL; Mori H; Mummery CJ; Niimi Y; Ringman JM; Salloway S; Schofield PR; Shoji M; Lott IT; ;
    Lancet Neurol; 2021 Aug; 20(8):615-626. PubMed ID: 34302786
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Influence of the amyloid precursor protein locus on dementia in Down syndrome.
    Margallo-Lana M; Morris CM; Gibson AM; Tan AL; Kay DW; Tyrer SP; Moore BP; Ballard CG
    Neurology; 2004 Jun; 62(11):1996-8. PubMed ID: 15184603
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Association between genetic variants in sortilin-related receptor 1 (SORL1) and Alzheimer's disease in adults with Down syndrome.
    Lee JH; Chulikavit M; Pang D; Zigman WB; Silverman W; Schupf N
    Neurosci Lett; 2007 Sep; 425(2):105-9. PubMed ID: 17826910
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The discovery of Alzheimer-causing mutations in the APP gene and the formulation of the "amyloid cascade hypothesis".
    Hardy J
    FEBS J; 2017 Apr; 284(7):1040-1044. PubMed ID: 28054745
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Common genetic signatures of Alzheimer's disease in Down Syndrome.
    Sharma A; Chunduri A; Gopu A; Shatrowsky C; Crusio WE; Delprato A
    F1000Res; 2020; 9():1299. PubMed ID: 33633844
    [No Abstract]   [Full Text] [Related]  

  • 10. Chromosome 21q21 sublocalisation of gene encoding beta-amyloid peptide in cerebral vessels and neuritic (senile) plaques of people with Alzheimer disease and Down syndrome.
    Robakis NK; Wisniewski HM; Jenkins EC; Devine-Gage EA; Houck GE; Yao XL; Ramakrishna N; Wolfe G; Silverman WP; Brown WT
    Lancet; 1987 Feb; 1(8529):384-5. PubMed ID: 2880184
    [No Abstract]   [Full Text] [Related]  

  • 11. The role of amyloid beta-protein in Alzheimer's disease.
    Regland B; Gottfries CG
    Lancet; 1992 Aug; 340(8817):467-9. PubMed ID: 1354793
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Endosomal structure and APP biology are not altered in a preclinical mouse cellular model of Down syndrome.
    Cannavo C; Cleverley K; Maduro C; Mumford P; Moulding D; Fisher EMC; Wiseman FK
    PLoS One; 2022; 17(5):e0262558. PubMed ID: 35544526
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Down's syndrome and Alzheimer's disease: towards secondary prevention.
    Ness S; Rafii M; Aisen P; Krams M; Silverman W; Manji H
    Nat Rev Drug Discov; 2012 Sep; 11(9):655-6. PubMed ID: 22935789
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Genetic and host factors for dementia in Down's syndrome.
    Schupf N; Sergievsky GH
    Br J Psychiatry; 2002 May; 180():405-10. PubMed ID: 11983636
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Down syndrome.
    Takashima S
    Curr Opin Neurol; 1997 Apr; 10(2):148-52. PubMed ID: 9146996
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Low-degree trisomy 21 mosaicism promotes early-onset Alzheimer disease.
    Nuebling GS; Prix C; Brendel M; Beyer L; Wlasich E; Loosli SV; Barthel H; Sabri O; Bartenstein P; Vöglein J; Danek A; Rominger A; Edbauer D; Haass C; Levin J
    Neurobiol Aging; 2021 Jul; 103():147.e1-147.e5. PubMed ID: 33789815
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Targeting increased levels of APP in Down syndrome: Posiphen-mediated reductions in APP and its products reverse endosomal phenotypes in the Ts65Dn mouse model.
    Chen XQ; Salehi A; Pearn ML; Overk C; Nguyen PD; Kleschevnikov AM; Maccecchini M; Mobley WC
    Alzheimers Dement; 2021 Feb; 17(2):271-292. PubMed ID: 32975365
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Alzheimer's disease and chromosome 14. Different gene, same process?
    Harrison P
    Br J Psychiatry; 1993 Jul; 163():2-5. PubMed ID: 8353694
    [No Abstract]   [Full Text] [Related]  

  • 19. A causal role for amyloid in Alzheimer's disease: the end of the beginning.
    Rosenberg RN
    Neurology; 1993 May; 43(5):851-6. PubMed ID: 8492934
    [No Abstract]   [Full Text] [Related]  

  • 20. Patterns and severity of vascular amyloid in Alzheimer's disease associated with duplications and missense mutations in APP gene, Down syndrome and sporadic Alzheimer's disease.
    Mann DMA; Davidson YS; Robinson AC; Allen N; Hashimoto T; Richardson A; Jones M; Snowden JS; Pendleton N; Potier MC; Laquerrière A; Prasher V; Iwatsubo T; Strydom A
    Acta Neuropathol; 2018 Oct; 136(4):569-587. PubMed ID: 29770843
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 36.