BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

256 related articles for article (PubMed ID: 26245978)

  • 21. Molecular Mechanism of LEDGF/p75 Dimerization.
    Lux V; Brouns T; Čermáková K; Srb P; Fábry M; Mádlíková M; Hořejší M; Kukačka Z; Novák P; Kugler M; Brynda J; DeRijck J; Christ F; Debyser Z; Veverka V
    Structure; 2020 Dec; 28(12):1288-1299.e7. PubMed ID: 32946742
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Lens epithelium-derived growth factor/p75 prevents proteasomal degradation of HIV-1 integrase.
    Llano M; Delgado S; Vanegas M; Poeschla EM
    J Biol Chem; 2004 Dec; 279(53):55570-7. PubMed ID: 15475359
    [TBL] [Abstract][Full Text] [Related]  

  • 23. The selenium-containing drug ebselen potently disrupts LEDGF/p75-HIV-1 integrase interaction by targeting LEDGF/p75.
    Zhang DW; Yan HL; Xu XS; Xu L; Yin ZH; Chang S; Luo H
    J Enzyme Inhib Med Chem; 2020 Dec; 35(1):906-912. PubMed ID: 32228103
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Implication of serine residues 271, 273, and 275 in the human immunodeficiency virus type 1 cofactor activity of lens epithelium-derived growth factor/p75.
    Garcia-Rivera JA; Bueno MT; Morales E; Kugelman JR; Rodriguez DF; Llano M
    J Virol; 2010 Jan; 84(2):740-52. PubMed ID: 19889764
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The Structure-Specific Recognition Protein 1 Associates with Lens Epithelium-Derived Growth Factor Proteins and Modulates HIV-1 Replication.
    Lopez AP; Kugelman JR; Garcia-Rivera J; Urias E; Salinas SA; Fernandez-Zapico ME; Llano M
    J Mol Biol; 2016 Jul; 428(14):2814-31. PubMed ID: 27216501
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Identification and characterization of the chromatin-binding domains of the HIV-1 integrase interactor LEDGF/p75.
    Llano M; Vanegas M; Hutchins N; Thompson D; Delgado S; Poeschla EM
    J Mol Biol; 2006 Jul; 360(4):760-73. PubMed ID: 16793062
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Identification and characterization of a functional nuclear localization signal in the HIV-1 integrase interactor LEDGF/p75.
    Maertens G; Cherepanov P; Debyser Z; Engelborghs Y; Engelman A
    J Biol Chem; 2004 Aug; 279(32):33421-9. PubMed ID: 15163664
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Chromatinized templates reveal the requirement for the LEDGF/p75 PWWP domain during HIV-1 integration in vitro.
    Botbol Y; Raghavendra NK; Rahman S; Engelman A; Lavigne M
    Nucleic Acids Res; 2008 Mar; 36(4):1237-46. PubMed ID: 18174227
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The same pocket in menin binds both MLL and JUND but has opposite effects on transcription.
    Huang J; Gurung B; Wan B; Matkar S; Veniaminova NA; Wan K; Merchant JL; Hua X; Lei M
    Nature; 2012 Feb; 482(7386):542-6. PubMed ID: 22327296
    [TBL] [Abstract][Full Text] [Related]  

  • 30. [LEDGF/p75: a novel target for anti-HIV therapy and advances in the study of its related inhibitors].
    Chen WM; Liu XY
    Yao Xue Xue Bao; 2009 Sep; 44(9):953-60. PubMed ID: 20055168
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Evaluation of a flavonoid library for inhibition of interaction of HIV-1 integrase with human LEDGF/p75 towards a structure-activity relationship.
    Yin ZH; Yan HL; Pan Y; Zhang DW; Yan X
    Ann Med; 2022 Dec; 54(1):1590-1600. PubMed ID: 35658757
    [No Abstract]   [Full Text] [Related]  

  • 32. In vitro DNA tethering of HIV-1 integrase by the transcriptional coactivator LEDGF/p75.
    McNeely M; Hendrix J; Busschots K; Boons E; Deleersnijder A; Gerard M; Christ F; Debyser Z
    J Mol Biol; 2011 Jul; 410(5):811-30. PubMed ID: 21763490
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Affinities between the binding partners of the HIV-1 integrase dimer-lens epithelium-derived growth factor (IN dimer-LEDGF) complex.
    Tsiang M; Jones GS; Hung M; Mukund S; Han B; Liu X; Babaoglu K; Lansdon E; Chen X; Todd J; Cai T; Pagratis N; Sakowicz R; Geleziunas R
    J Biol Chem; 2009 Nov; 284(48):33580-99. PubMed ID: 19801648
    [TBL] [Abstract][Full Text] [Related]  

  • 34. The LEDGF/p75 integrase interaction, a novel target for anti-HIV therapy.
    Christ F; Debyser Z
    Virology; 2013 Jan; 435(1):102-9. PubMed ID: 23217620
    [TBL] [Abstract][Full Text] [Related]  

  • 35. The interaction of LEDGF/p75 with integrase is lentivirus-specific and promotes DNA binding.
    Busschots K; Vercammen J; Emiliani S; Benarous R; Engelborghs Y; Christ F; Debyser Z
    J Biol Chem; 2005 May; 280(18):17841-7. PubMed ID: 15749713
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The transcriptional co-activator LEDGF/p75 displays a dynamic scan-and-lock mechanism for chromatin tethering.
    Hendrix J; Gijsbers R; De Rijck J; Voet A; Hotta J; McNeely M; Hofkens J; Debyser Z; Engelborghs Y
    Nucleic Acids Res; 2011 Mar; 39(4):1310-25. PubMed ID: 20974633
    [TBL] [Abstract][Full Text] [Related]  

  • 37. LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes.
    Llano M; Vanegas M; Fregoso O; Saenz D; Chung S; Peretz M; Poeschla EM
    J Virol; 2004 Sep; 78(17):9524-37. PubMed ID: 15308744
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Structure-based virtual screening toward the discovery of novel inhibitors for impeding the protein-protein interaction between HIV-1 integrase and human lens epithelium-derived growth factor (LEDGF/p75).
    Panwar U; Singh SK
    J Biomol Struct Dyn; 2018 Sep; 36(12):3199-3217. PubMed ID: 28948865
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Insights into the interactions between HIV-1 integrase and human LEDGF/p75 by molecular dynamics simulation and free energy calculation.
    Zhao Y; Li W; Zeng J; Liu G; Tang Y
    Proteins; 2008 Aug; 72(2):635-45. PubMed ID: 18247352
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Identification of small peptides inhibiting the integrase-LEDGF/p75 interaction through targeting the cellular co-factor.
    Cavalluzzo C; Christ F; Voet A; Sharma A; Singh BK; Zhang KY; Lescrinier E; De Maeyer M; Debyser Z; Van der Eycken E
    J Pept Sci; 2013 Oct; 19(10):651-8. PubMed ID: 24014475
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.