These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

366 related articles for article (PubMed ID: 26252351)

  • 1. Sphingosine kinase inhibitors decrease viability and induce cell death in natural killer-large granular lymphocyte leukemia.
    LeBlanc FR; Liu X; Hengst J; Fox T; Calvert V; Petricoin EF; Yun J; Feith DJ; Loughran TP
    Cancer Biol Ther; 2015; 16(12):1830-40. PubMed ID: 26252351
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Sphingosine kinase-2 is overexpressed in large granular lymphocyte leukaemia and promotes survival through Mcl-1.
    LeBlanc FR; Pearson JM; Tan SF; Cheon H; Xing JC; Dunton W; Feith DJ; Loughran TP
    Br J Haematol; 2020 Aug; 190(3):405-417. PubMed ID: 32124438
    [TBL] [Abstract][Full Text] [Related]  

  • 3. SphK1 inhibitor II (SKI-II) inhibits acute myelogenous leukemia cell growth in vitro and in vivo.
    Yang L; Weng W; Sun ZX; Fu XJ; Ma J; Zhuang WF
    Biochem Biophys Res Commun; 2015 May; 460(4):903-8. PubMed ID: 25824043
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sphingosine kinase expression regulates apoptosis and caspase activation in PC12 cells.
    Edsall LC; Cuvillier O; Twitty S; Spiegel S; Milstien S
    J Neurochem; 2001 Mar; 76(5):1573-84. PubMed ID: 11238741
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A selective sphingosine kinase 1 inhibitor integrates multiple molecular therapeutic targets in human leukemia.
    Paugh SW; Paugh BS; Rahmani M; Kapitonov D; Almenara JA; Kordula T; Milstien S; Adams JK; Zipkin RE; Grant S; Spiegel S
    Blood; 2008 Aug; 112(4):1382-91. PubMed ID: 18511810
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The apoptotic mechanism of action of the sphingosine kinase 1 selective inhibitor SKI-178 in human acute myeloid leukemia cell lines.
    Dick TE; Hengst JA; Fox TE; Colledge AL; Kale VP; Sung SS; Sharma A; Amin S; Loughran TP; Kester M; Wang HG; Yun JK
    J Pharmacol Exp Ther; 2015 Mar; 352(3):494-508. PubMed ID: 25563902
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Vitamin D pathway activation selectively deactivates signal transducer and activator of transcription (STAT) proteins and inflammatory cytokine production in natural killer leukemic large granular lymphocytes.
    Olson KC; Kulling Larkin PM; Signorelli R; Hamele CE; Olson TL; Conaway MR; Feith DJ; Loughran TP
    Cytokine; 2018 Nov; 111():551-562. PubMed ID: 30455079
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Neuroprotective role of sphingolipid rheostat in excitotoxic retinal ganglion cell death.
    Nakamura N; Honjo M; Yamagishi R; Kurano M; Yatomi Y; Watanabe S; Aihara M
    Exp Eye Res; 2021 Jul; 208():108623. PubMed ID: 34022173
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Platelet-derived growth factor mediates survival of leukemic large granular lymphocytes via an autocrine regulatory pathway.
    Yang J; Liu X; Nyland SB; Zhang R; Ryland LK; Broeg K; Baab KT; Jarbadan NR; Irby R; Loughran TP
    Blood; 2010 Jan; 115(1):51-60. PubMed ID: 19880494
    [TBL] [Abstract][Full Text] [Related]  

  • 10. SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism.
    Maceyka M; Sankala H; Hait NC; Le Stunff H; Liu H; Toman R; Collier C; Zhang M; Satin LS; Merrill AH; Milstien S; Spiegel S
    J Biol Chem; 2005 Nov; 280(44):37118-29. PubMed ID: 16118219
    [TBL] [Abstract][Full Text] [Related]  

  • 11. ATP-binding cassette ABCC1 is involved in the release of sphingosine 1-phosphate from rat uterine leiomyoma ELT3 cells and late pregnant rat myometrium.
    Tanfin Z; Serrano-Sanchez M; Leiber D
    Cell Signal; 2011 Dec; 23(12):1997-2004. PubMed ID: 21803151
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Intrinsic and extrinsic mechanisms contribute to maintain the JAK/STAT pathway aberrantly activated in T-type large granular lymphocyte leukemia.
    Teramo A; Gattazzo C; Passeri F; Lico A; Tasca G; Cabrelle A; Martini V; Frezzato F; Trimarco V; Ave E; Boscaro E; Piazza F; Facco M; Trentin L; Semenzato G; Zambello R
    Blood; 2013 May; 121(19):3843-54, S1. PubMed ID: 23515927
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Molecular profiling of LGL leukemia reveals role of sphingolipid signaling in survival of cytotoxic lymphocytes.
    Shah MV; Zhang R; Irby R; Kothapalli R; Liu X; Arrington T; Frank B; Lee NH; Loughran TP
    Blood; 2008 Aug; 112(3):770-81. PubMed ID: 18477771
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia.
    Powell JA; Lewis AC; Zhu W; Toubia J; Pitman MR; Wallington-Beddoe CT; Moretti PA; Iarossi D; Samaraweera SE; Cummings N; Ramshaw HS; Thomas D; Wei AH; Lopez AF; D'Andrea RJ; Lewis ID; Pitson SM
    Blood; 2017 Feb; 129(6):771-782. PubMed ID: 27956387
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Sphingolipids and the sphingosine kinase inhibitor, SKI II, induce BCL-2-independent apoptosis in human prostatic adenocarcinoma cells.
    Leroux ME; Auzenne E; Evans R; Hail N; Spohn W; Ghosh SC; Farquhar D; McDonnell T; Klostergaard J
    Prostate; 2007 Nov; 67(15):1699-717. PubMed ID: 17879964
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeting sphingosine kinase-1 to inhibit melanoma.
    Madhunapantula SV; Hengst J; Gowda R; Fox TE; Yun JK; Robertson GP
    Pigment Cell Melanoma Res; 2012 Mar; 25(2):259-74. PubMed ID: 22236408
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A Pyrazolo[3,4-d]pyrimidine compound inhibits Fyn phosphorylation and induces apoptosis in natural killer cell leukemia.
    Laurenzana I; Caivano A; Trino S; De Luca L; La Rocca F; Simeon V; Tintori C; D'Alessio F; Teramo A; Zambello R; Traficante A; Maietti M; Semenzato G; Schenone S; Botta M; Musto P; Del Vecchio L
    Oncotarget; 2016 Oct; 7(40):65171-65184. PubMed ID: 27566560
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Targeting SphK1 as a new strategy against cancer.
    Shida D; Takabe K; Kapitonov D; Milstien S; Spiegel S
    Curr Drug Targets; 2008 Aug; 9(8):662-73. PubMed ID: 18691013
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TP53 is required for BECN1- and ATG5-dependent cell death induced by sphingosine kinase 1 inhibition.
    Lima S; Takabe K; Newton J; Saurabh K; Young MM; Leopoldino AM; Hait NC; Roberts JL; Wang HG; Dent P; Milstien S; Booth L; Spiegel S
    Autophagy; 2018; 14(6):942-957. PubMed ID: 29368980
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A sphingosine kinase-1 inhibitor, SKI-II, induces growth inhibition and apoptosis in human gastric cancer cells.
    Li PH; Wu JX; Zheng JN; Pei DS
    Asian Pac J Cancer Prev; 2014; 15(23):10381-5. PubMed ID: 25556479
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.