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7. Behavioral deficits and striatal DA signaling in LRRK2 p.G2019S transgenic rats: a multimodal investigation including PET neuroimaging. Walker MD; Volta M; Cataldi S; Dinelle K; Beccano-Kelly D; Munsie L; Kornelsen R; Mah C; Chou P; Co K; Khinda J; Mroczek M; Bergeron S; Yu K; Cao LP; Funk N; Ott T; Galter D; Riess O; Biskup S; Milnerwood AJ; Stoessl AJ; Farrer MJ; Sossi V J Parkinsons Dis; 2014; 4(3):483-98. PubMed ID: 25000966 [TBL] [Abstract][Full Text] [Related]
8. Age- and Sex-Dependent Behavioral and Neurochemical Alterations in hLRRK2-G2019S BAC Mice. Yao N; Skiteva O; Chergui K Biomolecules; 2022 Dec; 13(1):. PubMed ID: 36671436 [TBL] [Abstract][Full Text] [Related]
9. Adenoviral-mediated expression of G2019S LRRK2 induces striatal pathology in a kinase-dependent manner in a rat model of Parkinson's disease. Tsika E; Nguyen AP; Dusonchet J; Colin P; Schneider BL; Moore DJ Neurobiol Dis; 2015 May; 77():49-61. PubMed ID: 25731749 [TBL] [Abstract][Full Text] [Related]
10. Robust kinase- and age-dependent dopaminergic and norepinephrine neurodegeneration in LRRK2 G2019S transgenic mice. Xiong Y; Neifert S; Karuppagounder SS; Liu Q; Stankowski JN; Lee BD; Ko HS; Lee Y; Grima JC; Mao X; Jiang H; Kang SU; Swing DA; Iacovitti L; Tessarollo L; Dawson TM; Dawson VL Proc Natl Acad Sci U S A; 2018 Feb; 115(7):1635-1640. PubMed ID: 29386392 [TBL] [Abstract][Full Text] [Related]
11. (G2019S) LRRK2 activates MKK4-JNK pathway and causes degeneration of SN dopaminergic neurons in a transgenic mouse model of PD. Chen CY; Weng YH; Chien KY; Lin KJ; Yeh TH; Cheng YP; Lu CS; Wang HL Cell Death Differ; 2012 Oct; 19(10):1623-33. PubMed ID: 22539006 [TBL] [Abstract][Full Text] [Related]
12. Lack of CCR5 modifies glial phenotypes and population of the nigral dopaminergic neurons, but not MPTP-induced dopaminergic neurodegeneration. Choi DY; Lee MK; Hong JT Neurobiol Dis; 2013 Jan; 49():159-68. PubMed ID: 22922220 [TBL] [Abstract][Full Text] [Related]
13. Altered Development of Synapse Structure and Function in Striatum Caused by Parkinson's Disease-Linked LRRK2-G2019S Mutation. Matikainen-Ankney BA; Kezunovic N; Mesias RE; Tian Y; Williams FM; Huntley GW; Benson DL J Neurosci; 2016 Jul; 36(27):7128-41. PubMed ID: 27383589 [TBL] [Abstract][Full Text] [Related]
15. LRRK2 G2019S transgenic mice display increased susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-mediated neurotoxicity. Karuppagounder SS; Xiong Y; Lee Y; Lawless MC; Kim D; Nordquist E; Martin I; Ge P; Brahmachari S; Jhaldiyal A; Kumar M; Andrabi SA; Dawson TM; Dawson VL J Chem Neuroanat; 2016 Oct; 76(Pt B):90-97. PubMed ID: 26808467 [TBL] [Abstract][Full Text] [Related]
16. Genetic and pharmacological evidence that G2019S LRRK2 confers a hyperkinetic phenotype, resistant to motor decline associated with aging. Longo F; Russo I; Shimshek DR; Greggio E; Morari M Neurobiol Dis; 2014 Nov; 71():62-73. PubMed ID: 25107341 [TBL] [Abstract][Full Text] [Related]
17. Nigral injection of a proteasomal inhibitor, lactacystin, induces widespread glial cell activation and shows various phenotypes of Parkinson's disease in young and adult mouse. Savolainen MH; Albert K; Airavaara M; Myöhänen TT Exp Brain Res; 2017 Jul; 235(7):2189-2202. PubMed ID: 28439627 [TBL] [Abstract][Full Text] [Related]
18. LRRK2 enhances oxidative stress-induced neurotoxicity via its kinase activity. Heo HY; Park JM; Kim CH; Han BS; Kim KS; Seol W Exp Cell Res; 2010 Feb; 316(4):649-56. PubMed ID: 19769964 [TBL] [Abstract][Full Text] [Related]
19. Temporal expression of mutant LRRK2 in adult rats impairs dopamine reuptake. Zhou H; Huang C; Tong J; Hong WC; Liu YJ; Xia XG Int J Biol Sci; 2011; 7(6):753-61. PubMed ID: 21698001 [TBL] [Abstract][Full Text] [Related]
20. The C-terminal domain of LRRK2 with the G2019S mutation is sufficient to produce neurodegeneration of dopaminergic neurons in vivo. Cresto N; Gaillard MC; Gardier C; Gubinelli F; Diguet E; Bellet D; Legroux L; Mitja J; Auregan G; Guillermier M; Josephine C; Jan C; Dufour N; Joliot A; Hantraye P; Bonvento G; Déglon N; Bemelmans AP; Cambon K; Liot G; Brouillet E Neurobiol Dis; 2020 Feb; 134():104614. PubMed ID: 31605779 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]