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5. Genetic knock-down of HDAC3 does not modify disease-related phenotypes in a mouse model of Huntington's disease. Moumné L; Campbell K; Howland D; Ouyang Y; Bates GP PLoS One; 2012; 7(2):e31080. PubMed ID: 22347433 [TBL] [Abstract][Full Text] [Related]
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8. The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice. Thomas EA; Coppola G; Desplats PA; Tang B; Soragni E; Burnett R; Gao F; Fitzgerald KM; Borok JF; Herman D; Geschwind DH; Gottesfeld JM Proc Natl Acad Sci U S A; 2008 Oct; 105(40):15564-9. PubMed ID: 18829438 [TBL] [Abstract][Full Text] [Related]
9. Histone deacetylase (HDAC) inhibitors targeting HDAC3 and HDAC1 ameliorate polyglutamine-elicited phenotypes in model systems of Huntington's disease. Jia H; Pallos J; Jacques V; Lau A; Tang B; Cooper A; Syed A; Purcell J; Chen Y; Sharma S; Sangrey GR; Darnell SB; Plasterer H; Sadri-Vakili G; Gottesfeld JM; Thompson LM; Rusche JR; Marsh JL; Thomas EA Neurobiol Dis; 2012 May; 46(2):351-61. PubMed ID: 22590724 [TBL] [Abstract][Full Text] [Related]
10. SAHA decreases HDAC 2 and 4 levels in vivo and improves molecular phenotypes in the R6/2 mouse model of Huntington's disease. Mielcarek M; Benn CL; Franklin SA; Smith DL; Woodman B; Marks PA; Bates GP PLoS One; 2011; 6(11):e27746. PubMed ID: 22140466 [TBL] [Abstract][Full Text] [Related]
11. Epigenetic modifications as novel therapeutic targets for Huntington's disease. Wang F; Fischhaber PL; Guo C; Tang TS Epigenomics; 2014 Jun; 6(3):287-97. PubMed ID: 25111483 [TBL] [Abstract][Full Text] [Related]
12. Mechanisms of disease: Histone modifications in Huntington's disease. Sadri-Vakili G; Cha JH Nat Clin Pract Neurol; 2006 Jun; 2(6):330-8. PubMed ID: 16932577 [TBL] [Abstract][Full Text] [Related]
13. Epigenetic histone acetylation and deacetylation mechanisms in experimental models of neurodegenerative disorders. Konsoula Z; Barile FA J Pharmacol Toxicol Methods; 2012; 66(3):215-20. PubMed ID: 22902970 [TBL] [Abstract][Full Text] [Related]
14. Genetic knock-down of HDAC7 does not ameliorate disease pathogenesis in the R6/2 mouse model of Huntington's disease. Benn CL; Butler R; Mariner L; Nixon J; Moffitt H; Mielcarek M; Woodman B; Bates GP PLoS One; 2009 Jun; 4(6):e5747. PubMed ID: 19484127 [TBL] [Abstract][Full Text] [Related]
15. Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington's disease. Pallos J; Bodai L; Lukacsovich T; Purcell JM; Steffan JS; Thompson LM; Marsh JL Hum Mol Genet; 2008 Dec; 17(23):3767-75. PubMed ID: 18762557 [TBL] [Abstract][Full Text] [Related]
16. Modulating epigenetic HAT activity for reinstating acetylation homeostasis: A promising therapeutic strategy for neurological disorders. Ganai SA; Banday S; Farooq Z; Altaf M Pharmacol Ther; 2016 Oct; 166():106-22. PubMed ID: 27411674 [TBL] [Abstract][Full Text] [Related]
17. Epigenetics in Neurodegenerative Diseases: The Role of Histone Deacetylases. Sharma S; Sarathlal KC; Taliyan R CNS Neurol Disord Drug Targets; 2019; 18(1):11-18. PubMed ID: 30289079 [TBL] [Abstract][Full Text] [Related]
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20. Evaluation of histone deacetylase inhibitors as therapeutics for neurodegenerative diseases. Soragni E; Xu C; Cooper A; Plasterer HL; Rusche JR; Gottesfeld JM Methods Mol Biol; 2011; 793():495-508. PubMed ID: 21913121 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]