BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

150 related articles for article (PubMed ID: 26258875)

  • 1. FV-429 induces apoptosis and inhibits glycolysis by inhibiting Akt-mediated phosphorylation of hexokinase II in MDA-MB-231 cells.
    Zhou Y; Lu N; Qiao C; Ni T; Li Z; Yu B; Guo Q; Wei L
    Mol Carcinog; 2016 Sep; 55(9):1317-28. PubMed ID: 26258875
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Gen-27, a newly synthesized flavonoid, inhibits glycolysis and induces cell apoptosis via suppression of hexokinase II in human breast cancer cells.
    Tao L; Wei L; Liu Y; Ding Y; Liu X; Zhang X; Wang X; Yao Y; Lu J; Wang Q; Hu R
    Biochem Pharmacol; 2017 Feb; 125():12-25. PubMed ID: 27818240
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Flavonoid GL-V9 induces apoptosis and inhibits glycolysis of breast cancer via disrupting GSK-3β-modulated mitochondrial binding of HKII.
    Guo Y; Wei L; Zhou Y; Lu N; Tang X; Li Z; Wang X
    Free Radic Biol Med; 2020 Jan; 146():119-129. PubMed ID: 31669347
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Curcumin inhibits aerobic glycolysis and induces mitochondrial-mediated apoptosis through hexokinase II in human colorectal cancer cells in vitro.
    Wang K; Fan H; Chen Q; Ma G; Zhu M; Zhang X; Zhang Y; Yu J
    Anticancer Drugs; 2015 Jan; 26(1):15-24. PubMed ID: 25229889
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cerulenin-induced apoptosis is mediated by disrupting the interaction between AIF and hexokinase II.
    Jeong NY; Yoo YH
    Int J Oncol; 2012 Jun; 40(6):1949-56. PubMed ID: 22426850
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Glycolysis inhibition and apoptosis induction in human prostate cancer cells by FV-429-mediated regulation of AR-AKT-HK2 signaling network.
    Chen X; Wei L; Yang L; Guo W; Guo Q; Zhou Y
    Food Chem Toxicol; 2020 Sep; 143():111517. PubMed ID: 32619556
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Caspase-dependent and caspase-independent induction of apoptosis in breast cancer by fucoidan via the PI3K/AKT/GSK3β pathway in vivo and in vitro.
    Xue M; Ji X; Xue C; Liang H; Ge Y; He X; Zhang L; Bian K; Zhang L
    Biomed Pharmacother; 2017 Oct; 94():898-908. PubMed ID: 28810530
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Astragaloside IV reduces neuronal apoptosis and parthanatos in ischemic injury by preserving mitochondrial hexokinase-II.
    Li Y; Yang Y; Zhao Y; Zhang J; Liu B; Jiao S; Zhang X
    Free Radic Biol Med; 2019 Feb; 131():251-263. PubMed ID: 30502455
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Gomisin J inhibits the glioma progression by inducing apoptosis and reducing HKII-regulated glycolysis.
    Li R; Yang W
    Biochem Biophys Res Commun; 2020 Aug; 529(1):15-22. PubMed ID: 32560813
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Reactive oxygen species-mitochondria pathway involved in FV-429-induced apoptosis in human hepatocellular carcinoma HepG2 cells.
    Yang Z; Qiang L; Wu T; Chen FH; Yang HY; Zhao Q; Zou MJ; Sun YJ; Li ZY; Guo QL
    Anticancer Drugs; 2011 Oct; 22(9):886-95. PubMed ID: 21730822
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Targeting VDAC-bound hexokinase II: a promising approach for concomitant anti-cancer therapy.
    Krasnov GS; Dmitriev AA; Lakunina VA; Kirpiy AA; Kudryavtseva AV
    Expert Opin Ther Targets; 2013 Oct; 17(10):1221-33. PubMed ID: 23984984
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Akt mediates mitochondrial protection in cardiomyocytes through phosphorylation of mitochondrial hexokinase-II.
    Miyamoto S; Murphy AN; Brown JH
    Cell Death Differ; 2008 Mar; 15(3):521-9. PubMed ID: 18064042
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Hirsutine induces apoptosis of human breast cancer MDA-MB-231 cells through mitochondrial pathway].
    Huang QW; Zhai NN; Huang T; Li DM
    Sheng Li Xue Bao; 2018 Feb; 70(1):40-46. PubMed ID: 29492513
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Wogonin induces apoptosis and down-regulates survivin in human breast cancer MCF-7 cells by modulating PI3K-AKT pathway.
    Huang KF; Zhang GD; Huang YQ; Diao Y
    Int Immunopharmacol; 2012 Feb; 12(2):334-41. PubMed ID: 22182776
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Chrysin inhibited tumor glycolysis and induced apoptosis in hepatocellular carcinoma by targeting hexokinase-2.
    Xu D; Jin J; Yu H; Zhao Z; Ma D; Zhang C; Jiang H
    J Exp Clin Cancer Res; 2017 Mar; 36(1):44. PubMed ID: 28320429
    [TBL] [Abstract][Full Text] [Related]  

  • 16. LYG-202 exerts antitumor effect on PI3K/Akt signaling pathway in human breast cancer cells.
    Zhao Y; Wang X; Sun Y; Zhou Y; Yin Y; Ding Y; Li Z; Guo Q; Lu N
    Apoptosis; 2015 Sep; 20(9):1253-69. PubMed ID: 26153346
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A new pyrrole based small molecule from Tinospora cordifolia induces apoptosis in MDA-MB-231 breast cancer cells via ROS mediated mitochondrial damage and restoration of p53 activity.
    Rashmi KC; Harsha Raj M; Paul M; Girish KS; Salimath BP; Aparna HS
    Chem Biol Interact; 2019 Feb; 299():120-130. PubMed ID: 30543781
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Fangchinoline inhibits cell proliferation via Akt/GSK-3beta/ cyclin D1 signaling and induces apoptosis in MDA-MB-231 breast cancer cells.
    Wang CD; Yuan CF; Bu YQ; Wu XM; Wan JY; Zhang L; Hu N; Liu XJ; Zu Y; Liu GL; Song FZ
    Asian Pac J Cancer Prev; 2014; 15(2):769-73. PubMed ID: 24568493
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of mitochondria-associated hexokinase II in cancer cell death induced by 3-bromopyruvate.
    Chen Z; Zhang H; Lu W; Huang P
    Biochim Biophys Acta; 2009 May; 1787(5):553-60. PubMed ID: 19285479
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Plant cyclopeptide RA-V kills human breast cancer cells by inducing mitochondria-mediated apoptosis through blocking PDK1-AKT interaction.
    Fang XY; Chen W; Fan JT; Song R; Wang L; Gu YH; Zeng GZ; Shen Y; Wu XF; Tan NH; Xu Q; Sun Y
    Toxicol Appl Pharmacol; 2013 Feb; 267(1):95-103. PubMed ID: 23274515
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.