588 related articles for article (PubMed ID: 26259639)
1. Pharmacological inhibition of lysosomes activates the MTORC1 signaling pathway in chondrocytes in an autophagy-independent manner.
Newton PT; Vuppalapati KK; Bouderlique T; Chagin AS
Autophagy; 2015; 11(9):1594-607. PubMed ID: 26259639
[TBL] [Abstract][Full Text] [Related]
2. Suppression of lysosome function induces autophagy via a feedback down-regulation of MTOR complex 1 (MTORC1) activity.
Li M; Khambu B; Zhang H; Kang JH; Chen X; Chen D; Vollmer L; Liu PQ; Vogt A; Yin XM
J Biol Chem; 2013 Dec; 288(50):35769-80. PubMed ID: 24174532
[TBL] [Abstract][Full Text] [Related]
3. PDMP, a ceramide analogue, acts as an inhibitor of mTORC1 by inducing its translocation from lysosome to endoplasmic reticulum.
Ode T; Podyma-Inoue KA; Terasawa K; Inokuchi JI; Kobayashi T; Watabe T; Izumi Y; Hara-Yokoyama M
Exp Cell Res; 2017 Jan; 350(1):103-114. PubMed ID: 27865938
[TBL] [Abstract][Full Text] [Related]
4. V-ATPase: a master effector of E2F1-mediated lysosomal trafficking, mTORC1 activation and autophagy.
Meo-Evoli N; Almacellas E; Massucci FA; Gentilella A; Ambrosio S; Kozma SC; Thomas G; Tauler A
Oncotarget; 2015 Sep; 6(29):28057-70. PubMed ID: 26356814
[TBL] [Abstract][Full Text] [Related]
5.
Shao Q; Yang M; Liang C; Ma L; Zhang W; Jiang Z; Luo J; Lee JK; Liang C; Chen JF
Autophagy; 2020 Sep; 16(9):1635-1650. PubMed ID: 31847700
[TBL] [Abstract][Full Text] [Related]
6. Chloroquine and bafilomycin A mimic lysosomal storage disorders and impair mTORC1 signalling.
Fedele AO; Proud CG
Biosci Rep; 2020 Apr; 40(4):. PubMed ID: 32285908
[TBL] [Abstract][Full Text] [Related]
7. Amino Acid Availability Modulates Vacuolar H+-ATPase Assembly.
Stransky LA; Forgac M
J Biol Chem; 2015 Nov; 290(45):27360-27369. PubMed ID: 26378229
[TBL] [Abstract][Full Text] [Related]
8. Epidermal growth factor-induced vacuolar (H+)-atpase assembly: a role in signaling via mTORC1 activation.
Xu Y; Parmar A; Roux E; Balbis A; Dumas V; Chevalier S; Posner BI
J Biol Chem; 2012 Jul; 287(31):26409-22. PubMed ID: 22689575
[TBL] [Abstract][Full Text] [Related]
9. Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signaling.
Valapala M; Wilson C; Hose S; Bhutto IA; Grebe R; Dong A; Greenbaum S; Gu L; Sengupta S; Cano M; Hackett S; Xu G; Lutty GA; Dong L; Sergeev Y; Handa JT; Campochiaro P; Wawrousek E; Zigler JS; Sinha D
Autophagy; 2014 Mar; 10(3):480-96. PubMed ID: 24468901
[TBL] [Abstract][Full Text] [Related]
10. MTORC1 coordinates the autophagy and apoptosis signaling in articular chondrocytes in osteoarthritic temporomandibular joint.
Yang H; Wen Y; Zhang M; Liu Q; Zhang H; Zhang J; Lu L; Ye T; Bai X; Xiao G; Wang M
Autophagy; 2020 Feb; 16(2):271-288. PubMed ID: 31007149
[TBL] [Abstract][Full Text] [Related]
11. Cucurbitacin E Induces Autophagy via Downregulating mTORC1 Signaling and Upregulating AMPK Activity.
Zha QB; Zhang XY; Lin QR; Xu LH; Zhao GX; Pan H; Zhou D; Ouyang DY; Liu ZH; He XH
PLoS One; 2015; 10(5):e0124355. PubMed ID: 25970614
[TBL] [Abstract][Full Text] [Related]
12. The GST-BHMT assay reveals a distinct mechanism underlying proteasome inhibition-induced macroautophagy in mammalian cells.
Rui YN; Xu Z; Chen Z; Zhang S
Autophagy; 2015; 11(5):812-32. PubMed ID: 25984893
[TBL] [Abstract][Full Text] [Related]
13. Activity-independent targeting of mTOR to lysosomes in primary osteoclasts.
Wang A; Carraro-Lacroix LR; Owen C; Gao B; Corey PN; Tyrrell P; Brumell JH; Voronov I
Sci Rep; 2017 Jun; 7(1):3005. PubMed ID: 28592812
[TBL] [Abstract][Full Text] [Related]
14. mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy.
Bartolomeo R; Cinque L; De Leonibus C; Forrester A; Salzano AC; Monfregola J; De Gennaro E; Nusco E; Azario I; Lanzara C; Serafini M; Levine B; Ballabio A; Settembre C
J Clin Invest; 2017 Oct; 127(10):3717-3729. PubMed ID: 28872463
[TBL] [Abstract][Full Text] [Related]
15. LAPTM4b recruits the LAT1-4F2hc Leu transporter to lysosomes and promotes mTORC1 activation.
Milkereit R; Persaud A; Vanoaica L; Guetg A; Verrey F; Rotin D
Nat Commun; 2015 May; 6():7250. PubMed ID: 25998567
[TBL] [Abstract][Full Text] [Related]
16. Autophagy modulates amino acid signaling network in myotubes: differential effects on mTORC1 pathway and the integrated stress response.
Yu X; Long YC
FASEB J; 2015 Feb; 29(2):394-407. PubMed ID: 25376834
[TBL] [Abstract][Full Text] [Related]
17. Lysosome Membrane Permeabilization and Disruption of the Molecular Target of Rapamycin (mTOR)-Lysosome Interaction Are Associated with the Inhibition of Lung Cancer Cell Proliferation by a Chloroquinoline Analog.
Sironi J; Aranda E; Nordstrøm LU; Schwartz EL
Mol Pharmacol; 2019 Jan; 95(1):127-138. PubMed ID: 30409790
[TBL] [Abstract][Full Text] [Related]
18. Orexin/hypocretin activates mTOR complex 1 (mTORC1) via an Erk/Akt-independent and calcium-stimulated lysosome v-ATPase pathway.
Wang Z; Liu S; Kakizaki M; Hirose Y; Ishikawa Y; Funato H; Yanagisawa M; Yu Y; Liu Q
J Biol Chem; 2014 Nov; 289(46):31950-31959. PubMed ID: 25278019
[TBL] [Abstract][Full Text] [Related]
19. Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity.
Carroll B; Maetzel D; Maddocks OD; Otten G; Ratcliff M; Smith GR; Dunlop EA; Passos JF; Davies OR; Jaenisch R; Tee AR; Sarkar S; Korolchuk VI
Elife; 2016 Jan; 5():. PubMed ID: 26742086
[TBL] [Abstract][Full Text] [Related]
20. Disruption of the vacuolar-type H
Kissing S; Rudnik S; Damme M; Lüllmann-Rauch R; Ichihara A; Kornak U; Eskelinen EL; Jabs S; Heeren J; De Brabander JK; Haas A; Saftig P
Autophagy; 2017 Apr; 13(4):670-685. PubMed ID: 28129027
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
