471 related articles for article (PubMed ID: 26259961)
1. Trace levels of the CHO host cell protease cathepsin D caused particle formation in a monoclonal antibody product.
Bee JS; Tie L; Johnson D; Dimitrova MN; Jusino KC; Afdahl CD
Biotechnol Prog; 2015; 31(5):1360-9. PubMed ID: 26259961
[TBL] [Abstract][Full Text] [Related]
2. Identification of an IgG CDR sequence contributing to co-purification of the host cell protease cathepsin D.
Bee JS; Machiesky LM; Peng L; Jusino KC; Dickson M; Gill J; Johnson D; Lin HY; Miller K; Heidbrink Thompson J; Remmele RL
Biotechnol Prog; 2017 Jan; 33(1):140-145. PubMed ID: 27798957
[TBL] [Abstract][Full Text] [Related]
3. Cathepsin D: Removal strategy on protein A chromatography, near real time monitoring and characterisation during monoclonal antibody production.
Cui T; Chi B; Heidbrink Thompson J; Kasali T; Sellick C; Turner R
J Biotechnol; 2019 Nov; 305():51-60. PubMed ID: 31442501
[TBL] [Abstract][Full Text] [Related]
4. Identification and characterization of co-purifying CHO host cell proteins in monoclonal antibody purification process.
Liu X; Chen Y; Zhao Y; Liu-Compton V; Chen W; Payne G; Lazar AC
J Pharm Biomed Anal; 2019 Sep; 174():500-508. PubMed ID: 31234041
[TBL] [Abstract][Full Text] [Related]
5. Discovery and characterization of CHO host cell protease-induced fragmentation of a recombinant monoclonal antibody during production process development.
Yang B; Li W; Zhao H; Wang A; Lei Y; Xie Q; Xiong S
J Chromatogr B Analyt Technol Biomed Life Sci; 2019 Apr; 1112():1-10. PubMed ID: 30836312
[TBL] [Abstract][Full Text] [Related]
6. Quantitative host cell protein analysis using two dimensional data independent LC-MS(E).
Farrell A; Mittermayr S; Morrissey B; Mc Loughlin N; Navas Iglesias N; Marison IW; Bones J
Anal Chem; 2015 Sep; 87(18):9186-93. PubMed ID: 26280711
[TBL] [Abstract][Full Text] [Related]
7. Factors affecting product association as a mechanism of host-cell protein persistence in bioprocessing.
Oh YH; Becker ML; Mendola KM; Choe LH; Min L; Lee KH; Yigzaw Y; Seay A; Bill J; Li X; Roush DJ; Cramer SM; Menegatti S; Lenhoff AM
Biotechnol Bioeng; 2024 Apr; 121(4):1284-1297. PubMed ID: 38240126
[TBL] [Abstract][Full Text] [Related]
8. A novel approach to monitor clearance of host cell proteins associated with monoclonal antibodies.
Aboulaich N; Chung WK; Thompson JH; Larkin C; Robbins D; Zhu M
Biotechnol Prog; 2014; 30(5):1114-24. PubMed ID: 25044920
[TBL] [Abstract][Full Text] [Related]
9. Identification and characterization of CHO host-cell proteins in monoclonal antibody bioprocessing.
Oh YH; Mendola KM; Choe LH; Min L; Lavoie AR; Sripada SA; Williams TI; Lee KH; Yigzaw Y; Seay A; Bill J; Li X; Roush DJ; Cramer SM; Menegatti S; Lenhoff AM
Biotechnol Bioeng; 2024 Jan; 121(1):291-305. PubMed ID: 37877536
[TBL] [Abstract][Full Text] [Related]
10. CHO cathepsin B identified as the protease responsible for a target bispecific antibody fragmentation.
Hu L; Liu S; Xia L; Cong X; Xu C; Wang L; Li Y
Protein Expr Purif; 2022 Nov; 199():106144. PubMed ID: 35839975
[TBL] [Abstract][Full Text] [Related]
11. Towards continuous mAb purification: Clearance of host cell proteins from CHO cell culture harvests via "flow-through affinity chromatography" using peptide-based adsorbents.
Sripada SA; Chu W; Williams TI; Teten MA; Mosley BJ; Carbonell RG; Lenhoff AM; Cramer SM; Bill J; Yigzaw Y; Roush DJ; Menegatti S
Biotechnol Bioeng; 2022 Jul; 119(7):1873-1889. PubMed ID: 35377460
[TBL] [Abstract][Full Text] [Related]
12. Fishing human monoclonal antibodies from a CHO cell supernatant with boronic acid magnetic particles.
Borlido L; Azevedo AM; Sousa AG; Oliveira PH; Roque AC; Aires-Barros MR
J Chromatogr B Analyt Technol Biomed Life Sci; 2012 Aug; 903():163-70. PubMed ID: 22857861
[TBL] [Abstract][Full Text] [Related]
13. Evaluating Immunogenicity Risk Due to Host Cell Protein Impurities in Antibody-Based Biotherapeutics.
Jawa V; Joubert MK; Zhang Q; Deshpande M; Hapuarachchi S; Hall MP; Flynn GC
AAPS J; 2016 Nov; 18(6):1439-1452. PubMed ID: 27450229
[TBL] [Abstract][Full Text] [Related]
14. A novel approach to characterize host cell proteins associated with therapeutic monoclonal antibodies.
Thomson AS; Mai S; Byrne MP
Biotechnol Bioeng; 2017 Jun; 114(6):1208-1214. PubMed ID: 28112396
[TBL] [Abstract][Full Text] [Related]
15. Characterization of the co-elution of host cell proteins with monoclonal antibodies during protein A purification.
Zhang Q; Goetze AM; Cui H; Wylie J; Tillotson B; Hewig A; Hall MP; Flynn GC
Biotechnol Prog; 2016 May; 32(3):708-17. PubMed ID: 27073178
[TBL] [Abstract][Full Text] [Related]
16. Formation of transient highly-charged mAb clusters strengthens interactions with host cell proteins and results in poor clearance of host cell proteins by protein A chromatography.
Luo H; Du Q; Qian C; Mlynarczyk M; Pabst TM; Damschroder M; Hunter AK; Wang WK
J Chromatogr A; 2022 Aug; 1679():463385. PubMed ID: 35933770
[TBL] [Abstract][Full Text] [Related]
17. Identification of a host cell protein impurity in therapeutic protein, P1.
Ahluwalia D; Dhillon H; Slaney T; Song H; Boux H; Mehta S; Zhang L; Valdez A; Krishnamurthy G
J Pharm Biomed Anal; 2017 Jul; 141():32-38. PubMed ID: 28419935
[TBL] [Abstract][Full Text] [Related]
18. Host cell protein impurities in chromatographic polishing steps for monoclonal antibody purification.
Levy NE; Valente KN; Lee KH; Lenhoff AM
Biotechnol Bioeng; 2016 Jun; 113(6):1260-72. PubMed ID: 26550778
[TBL] [Abstract][Full Text] [Related]
19. SWATH-MS as a strategy for CHO host cell protein identification and quantification supporting the characterization of mAb purification platforms.
Carvalho SB; Profit L; Krishnan S; Gomes RA; Alexandre BM; Clavier S; Hoffman M; Brower K; Gomes-Alves P
J Biotechnol; 2024 Mar; 384():1-11. PubMed ID: 38340900
[TBL] [Abstract][Full Text] [Related]
20. Targeted capture of Chinese hamster ovary host cell proteins: Peptide ligand binding by proteomic analysis.
Lavoie RA; di Fazio A; Williams TI; Carbonell R; Menegatti S
Biotechnol Bioeng; 2020 Feb; 117(2):438-452. PubMed ID: 31654407
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]