151 related articles for article (PubMed ID: 26266692)
1. Mutations Proximal to Sites of Autoproteolysis and the α-Helix That Co-evolve under Drug Pressure Modulate the Autoprocessing and Vitality of HIV-1 Protease.
Louis JM; Deshmukh L; Sayer JM; Aniana A; Clore GM
Biochemistry; 2015 Sep; 54(35):5414-24. PubMed ID: 26266692
[TBL] [Abstract][Full Text] [Related]
2. Enhanced stability of monomer fold correlates with extreme drug resistance of HIV-1 protease.
Louis JM; Tözsér J; Roche J; Matúz K; Aniana A; Sayer JM
Biochemistry; 2013 Oct; 52(43):7678-88. PubMed ID: 24079831
[TBL] [Abstract][Full Text] [Related]
3. Binding of Clinical Inhibitors to a Model Precursor of a Rationally Selected Multidrug Resistant HIV-1 Protease Is Significantly Weaker Than That to the Released Mature Enzyme.
Park JH; Sayer JM; Aniana A; Yu X; Weber IT; Harrison RW; Louis JM
Biochemistry; 2016 Apr; 55(16):2390-400. PubMed ID: 27039930
[TBL] [Abstract][Full Text] [Related]
4. Terminal interface conformations modulate dimer stability prior to amino terminal autoprocessing of HIV-1 protease.
Agniswamy J; Sayer JM; Weber IT; Louis JM
Biochemistry; 2012 Feb; 51(5):1041-50. PubMed ID: 22242794
[TBL] [Abstract][Full Text] [Related]
5. Multi-drug resistance profile of PR20 HIV-1 protease is attributed to distorted conformational and drug binding landscape: molecular dynamics insights.
Chetty S; Bhakat S; Martin AJ; Soliman ME
J Biomol Struct Dyn; 2016; 34(1):135-51. PubMed ID: 25671669
[TBL] [Abstract][Full Text] [Related]
6. Autoprocessing of HIV-1 protease is tightly coupled to protein folding.
Louis JM; Clore GM; Gronenborn AM
Nat Struct Biol; 1999 Sep; 6(9):868-75. PubMed ID: 10467100
[TBL] [Abstract][Full Text] [Related]
7. HIV-1 protease with leucine zipper fused at N-terminus exhibits enhanced linker amino acid-dependent activity.
Yu FH; Wang CT
Retrovirology; 2018 Apr; 15(1):32. PubMed ID: 29655366
[TBL] [Abstract][Full Text] [Related]
8. A Functional Interplay between Human Immunodeficiency Virus Type 1 Protease Residues 77 and 93 Involved in Differential Regulation of Precursor Autoprocessing and Mature Protease Activity.
Counts CJ; Ho PS; Donlin MJ; Tavis JE; Chen C
PLoS One; 2015; 10(4):e0123561. PubMed ID: 25893662
[TBL] [Abstract][Full Text] [Related]
9. Autoprocessing of human immunodeficiency virus type 1 protease miniprecursor fusions in mammalian cells.
Huang L; Chen C
AIDS Res Ther; 2010 Jul; 7():27. PubMed ID: 20667109
[TBL] [Abstract][Full Text] [Related]
10. Modulation of human immunodeficiency virus type 1 protease autoprocessing by charge properties of surface residue 69.
Huang L; Sayer JM; Swinford M; Louis JM; Chen C
J Virol; 2009 Aug; 83(15):7789-93. PubMed ID: 19457992
[TBL] [Abstract][Full Text] [Related]
11. Mechanism of dissociative inhibition of HIV protease and its autoprocessing from a precursor.
Sayer JM; Aniana A; Louis JM
J Mol Biol; 2012 Sep; 422(2):230-44. PubMed ID: 22659320
[TBL] [Abstract][Full Text] [Related]
12. Extreme multidrug resistant HIV-1 protease with 20 mutations is resistant to novel protease inhibitors with P1'-pyrrolidinone or P2-tris-tetrahydrofuran.
Agniswamy J; Shen CH; Wang YF; Ghosh AK; Rao KV; Xu CX; Sayer JM; Louis JM; Weber IT
J Med Chem; 2013 May; 56(10):4017-27. PubMed ID: 23590295
[TBL] [Abstract][Full Text] [Related]
13. Flexible catalytic site conformations implicated in modulation of HIV-1 protease autoprocessing reactions.
Huang L; Li Y; Chen C
Retrovirology; 2011 Oct; 8():79. PubMed ID: 21985091
[TBL] [Abstract][Full Text] [Related]
14. Substituted Bis-THF Protease Inhibitors with Improved Potency against Highly Resistant Mature HIV-1 Protease PR20.
Agniswamy J; Louis JM; Shen CH; Yashchuk S; Ghosh AK; Weber IT
J Med Chem; 2015 Jun; 58(12):5088-95. PubMed ID: 26010498
[TBL] [Abstract][Full Text] [Related]
15. Context-dependent autoprocessing of human immunodeficiency virus type 1 protease precursors.
Tien C; Huang L; Watanabe SM; Speidel JT; Carter CA; Chen C
PLoS One; 2018; 13(1):e0191372. PubMed ID: 29338056
[TBL] [Abstract][Full Text] [Related]
16. HIV-1 protease with 20 mutations exhibits extreme resistance to clinical inhibitors through coordinated structural rearrangements.
Agniswamy J; Shen CH; Aniana A; Sayer JM; Louis JM; Weber IT
Biochemistry; 2012 Apr; 51(13):2819-28. PubMed ID: 22404139
[TBL] [Abstract][Full Text] [Related]
17. Folding regulates autoprocessing of HIV-1 protease precursor.
Chatterjee A; Mridula P; Mishra RK; Mittal R; Hosur RV
J Biol Chem; 2005 Mar; 280(12):11369-78. PubMed ID: 15632156
[TBL] [Abstract][Full Text] [Related]
18. Systematic profiling of substrate binding response to multidrug-resistant mutations in HIV-1 protease: Implication for combating drug resistance.
Lv Y; Li J; Fang J; Jiao X; Yan L; Shan B
J Mol Graph Model; 2017 Jun; 74():83-88. PubMed ID: 28371730
[TBL] [Abstract][Full Text] [Related]
19. The L76V drug resistance mutation decreases the dimer stability and rate of autoprocessing of HIV-1 protease by reducing internal hydrophobic contacts.
Louis JM; Zhang Y; Sayer JM; Wang YF; Harrison RW; Weber IT
Biochemistry; 2011 May; 50(21):4786-95. PubMed ID: 21446746
[TBL] [Abstract][Full Text] [Related]
20. Evolution under Drug Pressure Remodels the Folding Free-Energy Landscape of Mature HIV-1 Protease.
Louis JM; Roche J
J Mol Biol; 2016 Jul; 428(13):2780-92. PubMed ID: 27170547
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
