BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

303 related articles for article (PubMed ID: 26272035)

  • 1. Identifying compound efficacy targets in phenotypic drug discovery.
    Schirle M; Jenkins JL
    Drug Discov Today; 2016 Jan; 21(1):82-89. PubMed ID: 26272035
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Target Identification of Compounds from a Cell Viability Phenotypic Screen Using a Bead/Lysate-Based Affinity Capture Platform.
    Tang H; Duggan S; Richardson PL; Marin V; Warder SE; McLoughlin SM
    J Biomol Screen; 2016 Feb; 21(2):201-11. PubMed ID: 26676096
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tools and methodologies capable of isolating and identifying a target molecule for a bioactive compound.
    Sakamoto S; Hatakeyama M; Ito T; Handa H
    Bioorg Med Chem; 2012 Mar; 20(6):1990-2001. PubMed ID: 22264760
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Finding the target after screening the phenotype.
    Hart CP
    Drug Discov Today; 2005 Apr; 10(7):513-9. PubMed ID: 15809197
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Chemoproteomic-enabled phenotypic screening.
    Conway LP; Li W; Parker CG
    Cell Chem Biol; 2021 Mar; 28(3):371-393. PubMed ID: 33577749
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Target identification of small molecules based on chemical biology approaches.
    Futamura Y; Muroi M; Osada H
    Mol Biosyst; 2013 May; 9(5):897-914. PubMed ID: 23354001
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Target identification of covalently binding drugs by activity-based protein profiling (ABPP).
    Pichler CM; Krysiak J; Breinbauer R
    Bioorg Med Chem; 2016 Aug; 24(15):3291-303. PubMed ID: 27085673
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Modern drug discovery technologies: opportunities and challenges in lead discovery.
    Guido RV; Oliva G; Andricopulo AD
    Comb Chem High Throughput Screen; 2011 Dec; 14(10):830-9. PubMed ID: 21843147
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Role of Historical Bioactivity Data in the Deconvolution of Phenotypic Screens.
    Bornot A; Blackett C; Engkvist O; Murray C; Bendtsen C
    J Biomol Screen; 2014 Jun; 19(5):696-706. PubMed ID: 24441646
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The chemical basis of pharmacology.
    Keiser MJ; Irwin JJ; Shoichet BK
    Biochemistry; 2010 Dec; 49(48):10267-76. PubMed ID: 21058655
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Network-based technologies for early drug discovery.
    Fotis C; Antoranz A; Hatziavramidis D; Sakellaropoulos T; Alexopoulos LG
    Drug Discov Today; 2018 Mar; 23(3):626-635. PubMed ID: 29294361
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Development of an assay for Complex I/Complex III of the respiratory chain using solid supported membranes and its application in mitochondrial toxicity screening in drug discovery.
    Preissl S; Bick I; Obrdlik P; Diekert K; Gul S; Gribbon P
    Assay Drug Dev Technol; 2011 Apr; 9(2):147-56. PubMed ID: 21133681
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Accelerated drug discovery by rapid candidate drug identification.
    Bergström F; Lindmark B
    Drug Discov Today; 2019 Jun; 24(6):1237-1241. PubMed ID: 30946980
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Approaches to protozoan drug discovery: phenotypic screening.
    Sykes ML; Avery VM
    J Med Chem; 2013 Oct; 56(20):7727-40. PubMed ID: 23927763
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Target deconvolution techniques in modern phenotypic profiling.
    Lee J; Bogyo M
    Curr Opin Chem Biol; 2013 Feb; 17(1):118-26. PubMed ID: 23337810
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Biodiversity of small molecules--a new perspective in screening set selection.
    Petrone PM; Wassermann AM; Lounkine E; Kutchukian P; Simms B; Jenkins J; Selzer P; Glick M
    Drug Discov Today; 2013 Jul; 18(13-14):674-80. PubMed ID: 23454345
    [TBL] [Abstract][Full Text] [Related]  

  • 17. High-content phenotypic and pathway profiling to advance drug discovery in diseases of unmet need.
    Hughes RE; Elliott RJR; Dawson JC; Carragher NO
    Cell Chem Biol; 2021 Mar; 28(3):338-355. PubMed ID: 33740435
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Quantitative Prioritization of Tool Compounds for Phenotypic Screening.
    Wang Y; Jenkins JL
    Methods Mol Biol; 2018; 1787():195-206. PubMed ID: 29736720
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Monitoring global growth of activity cliff information over time and assessing activity cliff frequencies and distributions.
    Stumpfe D; Bajorath J
    Future Med Chem; 2015 Aug; 7(12):1565-79. PubMed ID: 26334207
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Chemotography for multi-target SAR analysis in the context of biological pathways.
    Lounkine E; Kutchukian P; Petrone P; Davies JW; Glick M
    Bioorg Med Chem; 2012 Sep; 20(18):5416-27. PubMed ID: 22405595
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.