BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

579 related articles for article (PubMed ID: 26272943)

  • 1. Amyloid fibrils are the molecular trigger of inflammation in Parkinson's disease.
    Gustot A; Gallea JI; Sarroukh R; Celej MS; Ruysschaert JM; Raussens V
    Biochem J; 2015 Nov; 471(3):323-33. PubMed ID: 26272943
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MicroRNA-7 targets Nod-like receptor protein 3 inflammasome to modulate neuroinflammation in the pathogenesis of Parkinson's disease.
    Zhou Y; Lu M; Du RH; Qiao C; Jiang CY; Zhang KZ; Ding JH; Hu G
    Mol Neurodegener; 2016 Apr; 11():28. PubMed ID: 27084336
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of innate immunity by lysozyme fibrils is critically dependent on cross-β sheet structure.
    Gustot A; Raussens V; Dehousse M; Dumoulin M; Bryant CE; Ruysschaert JM; Lonez C
    Cell Mol Life Sci; 2013 Aug; 70(16):2999-3012. PubMed ID: 23334185
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Triggering of inflammasome by aggregated α-synuclein, an inflammatory response in synucleinopathies.
    Codolo G; Plotegher N; Pozzobon T; Brucale M; Tessari I; Bubacco L; de Bernard M
    PLoS One; 2013; 8(1):e55375. PubMed ID: 23383169
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The nucleotide-binding domain and leucine-rich repeat protein-3 inflammasome is not activated in airway smooth muscle upon toll-like receptor-2 ligation.
    Hirota JA; Im H; Rahman MM; Rumzhum NN; Manetsch M; Pascoe CD; Bunge K; Alkhouri H; Oliver BG; Ammit AJ
    Am J Respir Cell Mol Biol; 2013 Oct; 49(4):517-24. PubMed ID: 23614732
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeting Microglial α-Synuclein/TLRs/NF-kappaB/NLRP3 Inflammasome Axis in Parkinson's Disease.
    Li Y; Xia Y; Yin S; Wan F; Hu J; Kou L; Sun Y; Wu J; Zhou Q; Huang J; Xiong N; Wang T
    Front Immunol; 2021; 12():719807. PubMed ID: 34691027
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Serum amyloid A activates the NLRP3 inflammasome via P2X7 receptor and a cathepsin B-sensitive pathway.
    Niemi K; Teirilä L; Lappalainen J; Rajamäki K; Baumann MH; Öörni K; Wolff H; Kovanen PT; Matikainen S; Eklund KK
    J Immunol; 2011 Jun; 186(11):6119-28. PubMed ID: 21508263
    [TBL] [Abstract][Full Text] [Related]  

  • 8. α-Synuclein evokes NLRP3 inflammasome-mediated IL-1β secretion from primary human microglia.
    Pike AF; Varanita T; Herrebout MAC; Plug BC; Kole J; Musters RJP; Teunissen CE; Hoozemans JJM; Bubacco L; Veerhuis R
    Glia; 2021 Jun; 69(6):1413-1428. PubMed ID: 33506583
    [TBL] [Abstract][Full Text] [Related]  

  • 9. C-terminal truncation exacerbates the aggregation and cytotoxicity of α-Synuclein: A vicious cycle in Parkinson's disease.
    Ma L; Yang C; Zhang X; Li Y; Wang S; Zheng L; Huang K
    Biochim Biophys Acta Mol Basis Dis; 2018 Dec; 1864(12):3714-3725. PubMed ID: 30290273
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Dl-3-n-Butylphthalide Rescues Dopaminergic Neurons in Parkinson's Disease Models by Inhibiting the NLRP3 Inflammasome and Ameliorating Mitochondrial Impairment.
    Que R; Zheng J; Chang Z; Zhang W; Li H; Xie Z; Huang Z; Wang HT; Xu J; Jin D; Yang W; Tan EK; Wang Q
    Front Immunol; 2021; 12():794770. PubMed ID: 34925379
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Binding of Noradrenaline to Native and Intermediate States during the Fibrillation of α-Synuclein Leads to the Formation of Stable and Structured Cytotoxic Species.
    Singh P; Bhat R
    ACS Chem Neurosci; 2019 Jun; 10(6):2741-2755. PubMed ID: 30917654
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mechanistic basis for receptor-mediated pathological α-synuclein fibril cell-to-cell transmission in Parkinson's disease.
    Zhang S; Liu YQ; Jia C; Lim YJ; Feng G; Xu E; Long H; Kimura Y; Tao Y; Zhao C; Wang C; Liu Z; Hu JJ; Ma MR; Liu Z; Jiang L; Li D; Wang R; Dawson VL; Dawson TM; Li YM; Mao X; Liu C
    Proc Natl Acad Sci U S A; 2021 Jun; 118(26):. PubMed ID: 34172566
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Soluble α-synuclein-antibody complexes activate the NLRP3 inflammasome in hiPSC-derived microglia.
    Trudler D; Nazor KL; Eisele YS; Grabauskas T; Dolatabadi N; Parker J; Sultan A; Zhong Z; Goodwin MS; Levites Y; Golde TE; Kelly JW; Sierks MR; Schork NJ; Karin M; Ambasudhan R; Lipton SA
    Proc Natl Acad Sci U S A; 2021 Apr; 118(15):. PubMed ID: 33833060
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Echinacoside exerts neuroprotection via suppressing microglial α-synuclein/TLR2/NF-κB/NLRP3 axis in parkinsonian models.
    Yang XP; Huang JH; Ye FL; Yv QY; Chen S; Li WW; Zhu M
    Phytomedicine; 2024 Jan; 123():155230. PubMed ID: 38000105
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Alteration of Structure and Aggregation of α-Synuclein by Familial Parkinson's Disease Associated Mutations.
    Sahay S; Ghosh D; Singh PK; Maji SK
    Curr Protein Pept Sci; 2017; 18(7):656-676. PubMed ID: 26972727
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Toll-like receptors and NLRP3 inflammasome-dependent pathways in Parkinson's disease: mechanisms and therapeutic implications.
    Soraci L; Gambuzza ME; Biscetti L; Laganà P; Lo Russo C; Buda A; Barresi G; Corsonello A; Lattanzio F; Lorello G; Filippelli G; Marino S
    J Neurol; 2023 Mar; 270(3):1346-1360. PubMed ID: 36460875
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Protein denaturation and aggregation: Cellular responses to denatured and aggregated proteins.
    Meredith SC
    Ann N Y Acad Sci; 2005 Dec; 1066():181-221. PubMed ID: 16533927
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural remodeling during amyloidogenesis of physiological Nα-acetylated α-synuclein.
    Gallea JI; Sarroukh R; Yunes-Quartino P; Ruysschaert JM; Raussens V; Celej MS
    Biochim Biophys Acta; 2016 May; 1864(5):501-10. PubMed ID: 26845568
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Lipoteichoic acid modulates inflammatory response in macrophages after phagocytosis of titanium particles through Toll-like receptor 2 cascade and inflammasomes.
    Naganuma Y; Takakubo Y; Hirayama T; Tamaki Y; Pajarinen J; Sasaki K; Goodman SB; Takagi M
    J Biomed Mater Res A; 2016 Feb; 104(2):435-44. PubMed ID: 26440284
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biasing the native α-synuclein conformational ensemble towards compact states abolishes aggregation and neurotoxicity.
    Carija A; Pinheiro F; Pujols J; Brás IC; Lázaro DF; Santambrogio C; Grandori R; Outeiro TF; Navarro S; Ventura S
    Redox Biol; 2019 Apr; 22():101135. PubMed ID: 30769283
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 29.