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4. p62 is a key regulator of nutrient sensing in the mTORC1 pathway. Duran A; Amanchy R; Linares JF; Joshi J; Abu-Baker S; Porollo A; Hansen M; Moscat J; Diaz-Meco MT Mol Cell; 2011 Oct; 44(1):134-46. PubMed ID: 21981924 [TBL] [Abstract][Full Text] [Related]
5. Metabolic reprogramming of stromal fibroblasts through p62-mTORC1 signaling promotes inflammation and tumorigenesis. Valencia T; Kim JY; Abu-Baker S; Moscat-Pardos J; Ahn CS; Reina-Campos M; Duran A; Castilla EA; Metallo CM; Diaz-Meco MT; Moscat J Cancer Cell; 2014 Jul; 26(1):121-135. PubMed ID: 25002027 [TBL] [Abstract][Full Text] [Related]
6. The ubiquitination of rag A GTPase by RNF152 negatively regulates mTORC1 activation. Deng L; Jiang C; Chen L; Jin J; Wei J; Zhao L; Chen M; Pan W; Xu Y; Chu H; Wang X; Ge X; Li D; Liao L; Liu M; Li L; Wang P Mol Cell; 2015 Jun; 58(5):804-18. PubMed ID: 25936802 [TBL] [Abstract][Full Text] [Related]
7. Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy. Ichimura Y; Waguri S; Sou YS; Kageyama S; Hasegawa J; Ishimura R; Saito T; Yang Y; Kouno T; Fukutomi T; Hoshii T; Hirao A; Takagi K; Mizushima T; Motohashi H; Lee MS; Yoshimori T; Tanaka K; Yamamoto M; Komatsu M Mol Cell; 2013 Sep; 51(5):618-31. PubMed ID: 24011591 [TBL] [Abstract][Full Text] [Related]
8. p62/SQSTM1 functions as a signaling hub and an autophagy adaptor. Katsuragi Y; Ichimura Y; Komatsu M FEBS J; 2015 Dec; 282(24):4672-8. PubMed ID: 26432171 [TBL] [Abstract][Full Text] [Related]
9. Autophagy modulates amino acid signaling network in myotubes: differential effects on mTORC1 pathway and the integrated stress response. Yu X; Long YC FASEB J; 2015 Feb; 29(2):394-407. PubMed ID: 25376834 [TBL] [Abstract][Full Text] [Related]
10. The LIM protein Ajuba influences interleukin-1-induced NF-kappaB activation by affecting the assembly and activity of the protein kinase Czeta/p62/TRAF6 signaling complex. Feng Y; Longmore GD Mol Cell Biol; 2005 May; 25(10):4010-22. PubMed ID: 15870274 [TBL] [Abstract][Full Text] [Related]
11. Requirement for lysosomal localization of mTOR for its activation differs between leucine and other amino acids. Averous J; Lambert-Langlais S; Carraro V; Gourbeyre O; Parry L; B'Chir W; Muranishi Y; Jousse C; Bruhat A; Maurin AC; Proud CG; Fafournoux P Cell Signal; 2014 Sep; 26(9):1918-27. PubMed ID: 24793303 [TBL] [Abstract][Full Text] [Related]
12. Pharmacological inhibition of lysosomes activates the MTORC1 signaling pathway in chondrocytes in an autophagy-independent manner. Newton PT; Vuppalapati KK; Bouderlique T; Chagin AS Autophagy; 2015; 11(9):1594-607. PubMed ID: 26259639 [TBL] [Abstract][Full Text] [Related]
13. TSC but not PTEN loss in starving cones of retinitis pigmentosa mice leads to an autophagy defect and mTORC1 dissociation from the lysosome. Venkatesh A; Ma S; Punzo C Cell Death Dis; 2016 Jun; 7(6):e2279. PubMed ID: 27362797 [TBL] [Abstract][Full Text] [Related]
14. Metabolism. Differential regulation of mTORC1 by leucine and glutamine. Jewell JL; Kim YC; Russell RC; Yu FX; Park HW; Plouffe SW; Tagliabracci VS; Guan KL Science; 2015 Jan; 347(6218):194-8. PubMed ID: 25567907 [TBL] [Abstract][Full Text] [Related]
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18. Skp2-Mediated RagA Ubiquitination Elicits a Negative Feedback to Prevent Amino-Acid-Dependent mTORC1 Hyperactivation by Recruiting GATOR1. Jin G; Lee SW; Zhang X; Cai Z; Gao Y; Chou PC; Rezaeian AH; Han F; Wang CY; Yao JC; Gong Z; Chan CH; Huang CY; Tsai FJ; Tsai CH; Tu SH; Wu CH; Sarbassov dos D; Ho YS; Lin HK Mol Cell; 2015 Jun; 58(6):989-1000. PubMed ID: 26051179 [TBL] [Abstract][Full Text] [Related]
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20. Rheb and Rags come together at the lysosome to activate mTORC1. Groenewoud MJ; Zwartkruis FJ Biochem Soc Trans; 2013 Aug; 41(4):951-5. PubMed ID: 23863162 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]