BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

276 related articles for article (PubMed ID: 26279575)

  • 21. The PtdIns3-phosphatase MTMR3 interacts with mTORC1 and suppresses its activity.
    Hao F; Itoh T; Morita E; Shirahama-Noda K; Yoshimori T; Noda T
    FEBS Lett; 2016 Jan; 590(1):161-73. PubMed ID: 26787466
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Expression of the autophagy substrate SQSTM1/p62 is restored during prolonged starvation depending on transcriptional upregulation and autophagy-derived amino acids.
    Sahani MH; Itakura E; Mizushima N
    Autophagy; 2014 Mar; 10(3):431-41. PubMed ID: 24394643
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Cucurbitacin E Induces Autophagy via Downregulating mTORC1 Signaling and Upregulating AMPK Activity.
    Zha QB; Zhang XY; Lin QR; Xu LH; Zhao GX; Pan H; Zhou D; Ouyang DY; Liu ZH; He XH
    PLoS One; 2015; 10(5):e0124355. PubMed ID: 25970614
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Combined regulation of mTORC1 and lysosomal acidification by GSK-3 suppresses autophagy and contributes to cancer cell growth.
    Azoulay-Alfaguter I; Elya R; Avrahami L; Katz A; Eldar-Finkelman H
    Oncogene; 2015 Aug; 34(35):4613-23. PubMed ID: 25500539
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Pancreatic β-cell failure mediated by mTORC1 hyperactivity and autophagic impairment.
    Bartolomé A; Kimura-Koyanagi M; Asahara S; Guillén C; Inoue H; Teruyama K; Shimizu S; Kanno A; García-Aguilar A; Koike M; Uchiyama Y; Benito M; Noda T; Kido Y
    Diabetes; 2014 Sep; 63(9):2996-3008. PubMed ID: 24740570
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Metabolic asymmetry in cancer: a "balancing act" that promotes tumor growth.
    Martinez-Outschoorn UE; Sotgia F; Lisanti MP
    Cancer Cell; 2014 Jul; 26(1):5-7. PubMed ID: 25026205
    [TBL] [Abstract][Full Text] [Related]  

  • 27. SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling.
    Kim YM; Stone M; Hwang TH; Kim YG; Dunlevy JR; Griffin TJ; Kim DH
    Mol Cell; 2012 Jun; 46(6):833-46. PubMed ID: 22575674
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Ras transformation uncouples the kinesin-coordinated cellular nutrient response.
    Zaganjor E; Weil LM; Gonzales JX; Minna JD; Cobb MH
    Proc Natl Acad Sci U S A; 2014 Jul; 111(29):10568-73. PubMed ID: 25002494
    [TBL] [Abstract][Full Text] [Related]  

  • 29. DAPK2 is a novel regulator of mTORC1 activity and autophagy.
    Ber Y; Shiloh R; Gilad Y; Degani N; Bialik S; Kimchi A
    Cell Death Differ; 2015 Mar; 22(3):465-75. PubMed ID: 25361081
    [TBL] [Abstract][Full Text] [Related]  

  • 30. p18/LAMTOR1: a late endosome/lysosome-specific anchor protein for the mTORC1/MAPK signaling pathway.
    Nada S; Mori S; Takahashi Y; Okada M
    Methods Enzymol; 2014; 535():249-63. PubMed ID: 24377928
    [TBL] [Abstract][Full Text] [Related]  

  • 31. High prevalence of mTOR complex activity can be targeted using Torin2 in papillary thyroid carcinoma.
    Ahmed M; Hussain AR; Bavi P; Ahmed SO; Al Sobhi SS; Al-Dayel F; Uddin S; Al-Kuraya KS
    Carcinogenesis; 2014 Jul; 35(7):1564-72. PubMed ID: 24583924
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Steady-state kinetic and inhibition studies of the mammalian target of rapamycin (mTOR) kinase domain and mTOR complexes.
    Tao Z; Barker J; Shi SD; Gehring M; Sun S
    Biochemistry; 2010 Oct; 49(39):8488-98. PubMed ID: 20804212
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Amino acid sensing and regulation of mTORC1.
    Yan L; Lamb RF
    Semin Cell Dev Biol; 2012 Aug; 23(6):621-5. PubMed ID: 22342805
    [TBL] [Abstract][Full Text] [Related]  

  • 34. TARDBP/TDP-43 regulates autophagy in both MTORC1-dependent and MTORC1-independent manners.
    Ying Z; Xia Q; Hao Z; Xu D; Wang M; Wang H; Wang G
    Autophagy; 2016; 12(4):707-8. PubMed ID: 27050460
    [TBL] [Abstract][Full Text] [Related]  

  • 35. p62 regulates CD40-mediated NFκB activation in macrophages through interaction with TRAF6.
    Seibold K; Ehrenschwender M
    Biochem Biophys Res Commun; 2015 Aug; 464(1):330-5. PubMed ID: 26133577
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Parkin ubiquitinates mTOR to regulate mTORC1 activity under mitochondrial stress.
    Park D; Lee MN; Jeong H; Koh A; Yang YR; Suh PG; Ryu SH
    Cell Signal; 2014 Oct; 26(10):2122-30. PubMed ID: 25007995
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Cellular signaling of amino acids towards mTORC1 activation in impaired human leucine catabolism.
    Schriever SC; Deutsch MJ; Adamski J; Roscher AA; Ensenauer R
    J Nutr Biochem; 2013 May; 24(5):824-31. PubMed ID: 22898570
    [TBL] [Abstract][Full Text] [Related]  

  • 38. p62 loss reprograms stromal metabolism to promote tumor growth.
    Cancer Discov; 2014 Sep; 4(9):OF17. PubMed ID: 25185199
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Quantitative phosphoproteomic analyses identify STK11IP as a lysosome-specific substrate of mTORC1 that regulates lysosomal acidification.
    Zi Z; Zhang Z; Feng Q; Kim C; Wang XD; Scherer PE; Gao J; Levine B; Yu Y
    Nat Commun; 2022 Apr; 13(1):1760. PubMed ID: 35365663
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Telomerase reverse transcriptase induces basal and amino acid starvation-induced autophagy through mTORC1.
    Ali M; Devkota S; Roh JI; Lee J; Lee HW
    Biochem Biophys Res Commun; 2016 Sep; 478(3):1198-204. PubMed ID: 27545609
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 14.