These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

695 related articles for article (PubMed ID: 26290635)

  • 1. Mechanisms of pyruvate kinase M2 isoform inhibits cell motility in hepatocellular carcinoma cells.
    Chen YL; Song JJ; Chen XC; Xu W; Zhi Q; Liu YP; Xu HZ; Pan JS; Ren JL; Guleng B
    World J Gastroenterol; 2015 Aug; 21(30):9093-102. PubMed ID: 26290635
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pyruvate kinase M2 plays a dual role on regulation of the EGF/EGFR signaling via E-cadherin-dependent manner in gastric cancer cells.
    Wang LY; Liu YP; Chen LG; Chen YL; Tan L; Liu JJ; Jazag A; Ren JL; Guleng B
    PLoS One; 2013; 8(6):e67542. PubMed ID: 23840737
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PKM2 promotes metastasis by recruiting myeloid-derived suppressor cells and indicates poor prognosis for hepatocellular carcinoma.
    Liu WR; Tian MX; Yang LX; Lin YL; Jin L; Ding ZB; Shen YH; Peng YF; Gao DM; Zhou J; Qiu SJ; Dai Z; He R; Fan J; Shi YH
    Oncotarget; 2015 Jan; 6(2):846-61. PubMed ID: 25514599
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pyruvate kinase M2 prevents apoptosis via modulating Bim stability and associates with poor outcome in hepatocellular carcinoma.
    Hu W; Lu SX; Li M; Zhang C; Liu LL; Fu J; Jin JT; Luo RZ; Zhang CZ; Yun JP
    Oncotarget; 2015 Mar; 6(9):6570-83. PubMed ID: 25788265
    [TBL] [Abstract][Full Text] [Related]  

  • 5. LNCAROD enhances hepatocellular carcinoma malignancy by activating glycolysis through induction of pyruvate kinase isoform PKM2.
    Jia G; Wang Y; Lin C; Lai S; Dai H; Wang Z; Dai L; Su H; Song Y; Zhang N; Feng Y; Tang B
    J Exp Clin Cancer Res; 2021 Sep; 40(1):299. PubMed ID: 34551796
    [TBL] [Abstract][Full Text] [Related]  

  • 6. PKM2 regulates hepatocellular carcinoma cell epithelial-mesenchymal transition and migration upon EGFR activation.
    Fan FT; Shen CS; Tao L; Tian C; Liu ZG; Zhu ZJ; Liu YP; Pei CS; Wu HY; Zhang L; Wang AY; Zheng SZ; Huang SL; Lu Y
    Asian Pac J Cancer Prev; 2014; 15(5):1961-70. PubMed ID: 24716919
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pyruvate Kinase M2 Knockdown Suppresses Migration, Invasion, and Epithelial-Mesenchymal Transition of Gastric Carcinoma via Hypoxia-Inducible Factor Alpha/B-Cell Lymphoma 6 Pathway.
    Li N; Meng D; Xu Y; Gao L; Shen F; Tie X; Zhang Y; Yi Z; Shen W; Liu Z; Xu Z
    Biomed Res Int; 2020; 2020():7467104. PubMed ID: 33376737
    [TBL] [Abstract][Full Text] [Related]  

  • 8. HSP90 promotes cell glycolysis, proliferation and inhibits apoptosis by regulating PKM2 abundance via Thr-328 phosphorylation in hepatocellular carcinoma.
    Xu Q; Tu J; Dou C; Zhang J; Yang L; Liu X; Lei K; Liu Z; Wang Y; Li L; Bao H; Wang J; Tu K
    Mol Cancer; 2017 Dec; 16(1):178. PubMed ID: 29262861
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pyruvate kinase M2 interacts with nuclear sterol regulatory element-binding protein 1a and thereby activates lipogenesis and cell proliferation in hepatocellular carcinoma.
    Zhao X; Zhao L; Yang H; Li J; Min X; Yang F; Liu J; Huang G
    J Biol Chem; 2018 Apr; 293(17):6623-6634. PubMed ID: 29514980
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Switching of pyruvate kinase isoform L to M2 promotes metabolic reprogramming in hepatocarcinogenesis.
    Wong CC; Au SL; Tse AP; Xu IM; Lai RK; Chiu DK; Wei LL; Fan DN; Tsang FH; Lo RC; Wong CM; Ng IO
    PLoS One; 2014; 9(12):e115036. PubMed ID: 25541689
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transforming Growth Factor-β Promotes Liver Tumorigenesis in Mice via Up-regulation of Snail.
    Moon H; Ju HL; Chung SI; Cho KJ; Eun JW; Nam SW; Han KH; Calvisi DF; Ro SW
    Gastroenterology; 2017 Nov; 153(5):1378-1391.e6. PubMed ID: 28734833
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mammalian Target of Rapamycin (mTOR) Regulates Transforming Growth Factor-β1 (TGF-β1)-Induced Epithelial-Mesenchymal Transition via Decreased Pyruvate Kinase M2 (PKM2) Expression in Cervical Cancer Cells.
    Cheng KY; Hao M
    Med Sci Monit; 2017 Apr; 23():2017-2028. PubMed ID: 28446743
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Eukaryotic elongation factor-1α 2 knockdown inhibits hepatocarcinogenesis by suppressing PI3K/Akt/NF-κB signaling.
    Qiu FN; Huang Y; Chen DY; Li F; Wu YA; Wu WB; Huang XL
    World J Gastroenterol; 2016 Apr; 22(16):4226-37. PubMed ID: 27122673
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Enhanced expression of the M2 isoform of pyruvate kinase is involved in gastric cancer development by regulating cancer-specific metabolism.
    Shiroki T; Yokoyama M; Tanuma N; Maejima R; Tamai K; Yamaguchi K; Oikawa T; Noguchi T; Miura K; Fujiya T; Shima H; Sato I; Murata-Kamiya N; Hatakeyama M; Iijima K; Shimosegawa T; Satoh K
    Cancer Sci; 2017 May; 108(5):931-940. PubMed ID: 28235245
    [TBL] [Abstract][Full Text] [Related]  

  • 15. miR-4417 Targets Tripartite Motif-Containing 35 (TRIM35) and Regulates Pyruvate Kinase Muscle 2 (PKM2) Phosphorylation to Promote Proliferation and Suppress Apoptosis in Hepatocellular Carcinoma Cells.
    Song L; Zhang W; Chang Z; Pan Y; Zong H; Fan Q; Wang L
    Med Sci Monit; 2017 Apr; 23():1741-1750. PubMed ID: 28394882
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 2,3'4,4',5-Pentachlorobiphenyl induces hepatocellular carcinoma cell proliferation through pyruvate kinase M2-dependent glycolysis.
    Liang W; Zhang Y; Song L; Li Z
    Toxicol Lett; 2019 Oct; 313():108-119. PubMed ID: 31251971
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Knockdown of pyruvate kinase type M2 suppresses tumor survival and invasion in osteosarcoma cells both in vitro and in vivo.
    Yuan Q; Yu H; Chen J; Song X; Sun L
    Exp Cell Res; 2018 Jan; 362(1):209-216. PubMed ID: 29155364
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pyruvate Kinase M2 Modulates Esophageal Squamous Cell Carcinoma Chemotherapy Response by Regulating the Pentose Phosphate Pathway.
    Fukuda S; Miyata H; Miyazaki Y; Makino T; Takahashi T; Kurokawa Y; Yamasaki M; Nakajima K; Takiguchi S; Mori M; Doki Y
    Ann Surg Oncol; 2015 Dec; 22 Suppl 3():S1461-8. PubMed ID: 25808097
    [TBL] [Abstract][Full Text] [Related]  

  • 19. COX-2 induces apoptosis-resistance in hepatocellular carcinoma cells via the HIF-1α/PKM2 pathway.
    Wang Q; Lu D; Fan L; Li Y; Liu Y; Yu H; Wang H; Liu J; Sun G
    Int J Mol Med; 2019 Jan; 43(1):475-488. PubMed ID: 30365092
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Metformin Inhibits TGF-β1-Induced Epithelial-to-Mesenchymal Transition via PKM2 Relative-mTOR/p70s6k Signaling Pathway in Cervical Carcinoma Cells.
    Cheng K; Hao M
    Int J Mol Sci; 2016 Nov; 17(12):. PubMed ID: 27916907
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 35.