BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

612 related articles for article (PubMed ID: 26292628)

  • 1. One-pot synthesis of podophyllotoxin-thiourea congeners by employing NH₂SO₃H/NaI: Anticancer activity, DNA topoisomerase-II inhibition, and apoptosis inducing agents.
    Shankaraiah N; Kumar NP; Amula SB; Nekkanti S; Jeengar MK; Naidu VG; Reddy TS; Kamal A
    Bioorg Med Chem Lett; 2015 Oct; 25(19):4239-44. PubMed ID: 26292628
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis of podophyllotoxin linked β-carboline congeners as potential anticancer agents and DNA topoisomerase II inhibitors.
    Sathish M; Kavitha B; Nayak VL; Tangella Y; Ajitha A; Nekkanti S; Alarifi A; Shankaraiah N; Nagesh N; Kamal A
    Eur J Med Chem; 2018 Jan; 144():557-571. PubMed ID: 29289881
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 4β-amidotriazole linked podophyllotoxin congeners: DNA topoisomerase-IIα inhibition and potential anticancer agents for prostate cancer.
    Reddy VG; Bonam SR; Reddy TS; Akunuri R; Naidu VGM; Nayak VL; Bhargava SK; Kumar HMS; Srihari P; Kamal A
    Eur J Med Chem; 2018 Jan; 144():595-611. PubMed ID: 29289884
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and evaluation of aroylthiourea derivatives of 4-β-amino-4'-O-demethyl-4-desoxypodophyllotoxin as novel topoisomerase II inhibitors.
    Zhao Y; Ge CW; Wu ZH; Wang CN; Fang JH; Zhu L
    Eur J Med Chem; 2011 Mar; 46(3):901-6. PubMed ID: 21277655
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 4β-[4'-(1-(Aryl)ureido)benzamide]podophyllotoxins as DNA topoisomerase I and IIα inhibitors and apoptosis inducing agents.
    Kamal A; Suresh P; Ramaiah MJ; Srinivasa Reddy T; Kapavarapu RK; Rao BN; Imthiajali S; Lakshminarayan Reddy T; Pushpavalli SN; Shankaraiah N; Pal-Bhadra M
    Bioorg Med Chem; 2013 Sep; 21(17):5198-208. PubMed ID: 23849207
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A rational design strategy of the novel topoisomerase II inhibitors for the synthesis of the 4-O-(2-pyrazinecarboxylic)-4'-demethylepipodophyllotoxin with antitumor activity by diminishing the relaxation reaction of topoisomerase II-DNA decatenation.
    Zhao W; Chen L; Li HM; Wang DJ; Li DS; Chen T; Yuan ZP; Tang YJ
    Bioorg Med Chem; 2014 Jun; 22(11):2998-3007. PubMed ID: 24775914
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis of 4β-N-polyaromatic substituted podophyllotoxins: DNA topoisomerase inhibition, anticancer and apoptosis-inducing activities.
    Kamal A; Kumar BA; Suresh P; Agrawal SK; Chashoo G; Singh SK; Saxena AK
    Bioorg Med Chem; 2010 Dec; 18(24):8493-500. PubMed ID: 21074444
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis and potent cytotoxic activity of novel podophyllotoxin derivatives.
    Li WQ; Wang XL; Qian K; Liu YQ; Wang CY; Yang L; Tian J; Morris-Natschke SL; Zhou XW; Lee KH
    Bioorg Med Chem; 2013 Apr; 21(8):2363-2369. PubMed ID: 23490151
    [TBL] [Abstract][Full Text] [Related]  

  • 9. An efficient one-pot synthesis of benzothiazolo-4β-anilino-podophyllotoxin congeners: DNA topoisomerase-II inhibition and anticancer activity.
    Kamal A; Kumar BA; Suresh P; Shankaraiah N; Kumar MS
    Bioorg Med Chem Lett; 2011 Jan; 21(1):350-3. PubMed ID: 21144748
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel ciprofloxacin hybrids using biology oriented drug synthesis (BIODS) approach: Anticancer activity, effects on cell cycle profile, caspase-3 mediated apoptosis, topoisomerase II inhibition, and antibacterial activity.
    Kassab AE; Gedawy EM
    Eur J Med Chem; 2018 Apr; 150():403-418. PubMed ID: 29547830
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design and synthesis of the novel DNA topoisomerase II inhibitors: esterification and amination substituted 4'-demethylepipodophyllotoxin derivates exhibiting anti-tumor activity by activating ATM/ATR signaling pathways.
    Xiao L; Zhao W; Li HM; Wan DJ; Li DS; Chen T; Tang YJ
    Eur J Med Chem; 2014 Jun; 80():267-77. PubMed ID: 24793877
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and antitumor activity of novel aroylthiourea derivatives of podophyllotoxin.
    Zhao Y; Wang C; Wu Z; Fang J; Zhu L
    Invest New Drugs; 2012 Feb; 30(1):17-24. PubMed ID: 20697773
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A novel epoxypropoxy flavonoid derivative and topoisomerase II inhibitor, MHY336, induces apoptosis in prostate cancer cells.
    Patra N; De U; Kang JA; Kim JM; Ahn MY; Lee J; Jung JH; Chung HY; Moon HR; Kim HS
    Eur J Pharmacol; 2011 May; 658(2-3):98-107. PubMed ID: 21376033
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological evaluation of 4β-sulphonamido and 4β-[(4'-sulphonamido)benzamide]podophyllotoxins as DNA topoisomerase-IIα and apoptosis inducing agents.
    Kamal A; Suresh P; Ramaiah MJ; Mallareddy A; Imthiajali S; Pushpavalli SN; Lavanya A; Pal-Bhadra M
    Bioorg Med Chem; 2012 Mar; 20(6):2054-66. PubMed ID: 22364746
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis, cytotoxicity and topoisomerase II inhibitory activity of lomefloxacin derivatives.
    Zhou Y; Xu X; Sun Y; Wang H; Sun H; You Q
    Bioorg Med Chem Lett; 2013 May; 23(10):2974-8. PubMed ID: 23566520
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and cytotoxic activity on human cancer cells of carbamate derivatives of 4β-(1,2,3-triazol-1-yl)podophyllotoxin.
    Liu JF; Sang CY; Xu XH; Zhang LL; Yang X; Hui L; Zhang JB; Chen SW
    Eur J Med Chem; 2013 Jun; 64():621-8. PubMed ID: 23711769
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 4β-[(4-Alkyl)-1,2,3-triazol-1-yl] podophyllotoxins as anticancer compounds: design, synthesis and biological evaluation.
    Reddy DM; Srinivas J; Chashoo G; Saxena AK; Sampath Kumar HM
    Eur J Med Chem; 2011 Jun; 46(6):1983-91. PubMed ID: 21477899
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and evaluation of etoposide and podophyllotoxin analogs against topoisomerase IIα and HCT-116 cells.
    Murphy MB; Kumar P; Bradley AM; Barton CE; Deweese JE; Mercer SL
    Bioorg Med Chem; 2020 Nov; 28(22):115773. PubMed ID: 33035756
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis, cytotoxicity, DNA binding and topoisomerase II inhibition of cassiarin A derivatives.
    Luesakul U; Palaga T; Krusong K; Ngamrojanavanich N; Vilaivan T; Puthong S; Muangsin N
    Bioorg Med Chem Lett; 2014 Jul; 24(13):2845-50. PubMed ID: 24835201
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Development of β-carboline-benzothiazole hybrids via carboxamide formation as cytotoxic agents: DNA intercalative topoisomerase IIα inhibition and apoptosis induction.
    Tokala R; Mahajan S; Kiranmai G; Sigalapalli DK; Sana S; John SE; Nagesh N; Shankaraiah N
    Bioorg Chem; 2021 Jan; 106():104481. PubMed ID: 33261848
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 31.