BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

400 related articles for article (PubMed ID: 26293809)

  • 1. Intracellular amyloid β oligomers impair organelle transport and induce dendritic spine loss in primary neurons.
    Umeda T; Ramser EM; Yamashita M; Nakajima K; Mori H; Silverman MA; Tomiyama T
    Acta Neuropathol Commun; 2015 Aug; 3():51. PubMed ID: 26293809
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Intracellular accumulation of toxic turn amyloid-β is associated with endoplasmic reticulum stress in Alzheimer's disease.
    Soejima N; Ohyagi Y; Nakamura N; Himeno E; Iinuma KM; Sakae N; Yamasaki R; Tabira T; Murakami K; Irie K; Kinoshita N; LaFerla FM; Kiyohara Y; Iwaki T; Kira J
    Curr Alzheimer Res; 2013 Jan; 10(1):11-20. PubMed ID: 22950910
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Linking amyloid-β and tau: amyloid-β induced synaptic dysfunction via local wreckage of the neuronal cytoskeleton.
    Zempel H; Mandelkow EM
    Neurodegener Dis; 2012; 10(1-4):64-72. PubMed ID: 22156588
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Intraneuronal APP and extracellular Aβ independently cause dendritic spine pathology in transgenic mouse models of Alzheimer's disease.
    Zou C; Montagna E; Shi Y; Peters F; Blazquez-Llorca L; Shi S; Filser S; Dorostkar MM; Herms J
    Acta Neuropathol; 2015 Jun; 129(6):909-20. PubMed ID: 25862638
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The CAMKK2-AMPK kinase pathway mediates the synaptotoxic effects of Aβ oligomers through Tau phosphorylation.
    Mairet-Coello G; Courchet J; Pieraut S; Courchet V; Maximov A; Polleux F
    Neuron; 2013 Apr; 78(1):94-108. PubMed ID: 23583109
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hypercholesterolemia accelerates intraneuronal accumulation of Aβ oligomers resulting in memory impairment in Alzheimer's disease model mice.
    Umeda T; Tomiyama T; Kitajima E; Idomoto T; Nomura S; Lambert MP; Klein WL; Mori H
    Life Sci; 2012 Dec; 91(23-24):1169-76. PubMed ID: 22273754
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Soluble Conformers of Aβ and Tau Alter Selective Proteins Governing Axonal Transport.
    Sherman MA; LaCroix M; Amar F; Larson ME; Forster C; Aguzzi A; Bennett DA; Ramsden M; Lesné SE
    J Neurosci; 2016 Sep; 36(37):9647-58. PubMed ID: 27629715
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Intracellular amyloid-β accumulation in calcium-binding protein-deficient neurons leads to amyloid-β plaque formation in animal model of Alzheimer's disease.
    Moon M; Hong HS; Nam DW; Baik SH; Song H; Kook SY; Kim YS; Lee J; Mook-Jung I
    J Alzheimers Dis; 2012; 29(3):615-28. PubMed ID: 22269161
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tau phosphorylation and tau mislocalization mediate soluble Aβ oligomer-induced AMPA glutamate receptor signaling deficits.
    Miller EC; Teravskis PJ; Dummer BW; Zhao X; Huganir RL; Liao D
    Eur J Neurosci; 2014 Apr; 39(7):1214-24. PubMed ID: 24713000
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Effect of Aβ Oligomers on Neuronal APP Triggers a Vicious Cycle Leading to the Propagation of Synaptic Plasticity Alterations to Healthy Neurons.
    Rolland M; Powell R; Jacquier-Sarlin M; Boisseau S; Reynaud-Dulaurier R; Martinez-Hernandez J; André L; Borel E; Buisson A; Lanté F
    J Neurosci; 2020 Jul; 40(27):5161-5176. PubMed ID: 32444385
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Familial Alzheimer's disease mutations at position 22 of the amyloid β-peptide sequence differentially affect synaptic loss, tau phosphorylation and neuronal cell death in an ex vivo system.
    Tackenberg C; Kulic L; Nitsch RM
    PLoS One; 2020; 15(9):e0239584. PubMed ID: 32966331
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines.
    Zempel H; Thies E; Mandelkow E; Mandelkow EM
    J Neurosci; 2010 Sep; 30(36):11938-50. PubMed ID: 20826658
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Modulation of insulin signaling rescues BDNF transport defects independent of tau in amyloid-β oligomer-treated hippocampal neurons.
    Takach O; Gill TB; Silverman MA
    Neurobiol Aging; 2015 Mar; 36(3):1378-82. PubMed ID: 25543463
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Amyloid beta induces the morphological neurodegenerative triad of spine loss, dendritic simplification, and neuritic dystrophies through calcineurin activation.
    Wu HY; Hudry E; Hashimoto T; Kuchibhotla K; Rozkalne A; Fan Z; Spires-Jones T; Xie H; Arbel-Ornath M; Grosskreutz CL; Bacskai BJ; Hyman BT
    J Neurosci; 2010 Feb; 30(7):2636-49. PubMed ID: 20164348
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The E693Δ (Osaka) mutation in amyloid precursor protein potentiates cholesterol-mediated intracellular amyloid β toxicity via its impaired cholesterol efflux.
    Nomura S; Umeda T; Tomiyama T; Mori H
    J Neurosci Res; 2013 Dec; 91(12):1541-50. PubMed ID: 24105984
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tau reduction prevents Abeta-induced defects in axonal transport.
    Vossel KA; Zhang K; Brodbeck J; Daub AC; Sharma P; Finkbeiner S; Cui B; Mucke L
    Science; 2010 Oct; 330(6001):198. PubMed ID: 20829454
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Beta-amyloid accumulation in APP mutant neurons reduces PSD-95 and GluR1 in synapses.
    Almeida CG; Tampellini D; Takahashi RH; Greengard P; Lin MT; Snyder EM; Gouras GK
    Neurobiol Dis; 2005 Nov; 20(2):187-98. PubMed ID: 16242627
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Rifampicin is a candidate preventive medicine against amyloid-β and tau oligomers.
    Umeda T; Ono K; Sakai A; Yamashita M; Mizuguchi M; Klein WL; Yamada M; Mori H; Tomiyama T
    Brain; 2016 May; 139(Pt 5):1568-86. PubMed ID: 27020329
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Neutralization of soluble, synaptotoxic amyloid β species by antibodies is epitope specific.
    Zago W; Buttini M; Comery TA; Nishioka C; Gardai SJ; Seubert P; Games D; Bard F; Schenk D; Kinney GG
    J Neurosci; 2012 Feb; 32(8):2696-702. PubMed ID: 22357853
    [TBL] [Abstract][Full Text] [Related]  

  • 20. NMDA receptor subunit composition determines beta-amyloid-induced neurodegeneration and synaptic loss.
    Tackenberg C; Grinschgl S; Trutzel A; Santuccione AC; Frey MC; Konietzko U; Grimm J; Brandt R; Nitsch RM
    Cell Death Dis; 2013 Apr; 4(4):e608. PubMed ID: 23618906
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.