187 related articles for article (PubMed ID: 26294764)
1. Two-step Ligand Binding in a (βα)8 Barrel Enzyme: SUBSTRATE-BOUND STRUCTURES SHED NEW LIGHT ON THE CATALYTIC CYCLE OF HisA.
Söderholm A; Guo X; Newton MS; Evans GB; Näsvall J; Patrick WM; Selmer M
J Biol Chem; 2015 Oct; 290(41):24657-68. PubMed ID: 26294764
[TBL] [Abstract][Full Text] [Related]
2. Directed evolution of a (beta alpha)8-barrel enzyme to catalyze related reactions in two different metabolic pathways.
Jürgens C; Strom A; Wegener D; Hettwer S; Wilmanns M; Sterner R
Proc Natl Acad Sci U S A; 2000 Aug; 97(18):9925-30. PubMed ID: 10944186
[TBL] [Abstract][Full Text] [Related]
3. Two (betaalpha)(8)-barrel enzymes of histidine and tryptophan biosynthesis have similar reaction mechanisms and common strategies for protecting their labile substrates.
Henn-Sax M; Thoma R; Schmidt S; Hennig M; Kirschner K; Sterner R
Biochemistry; 2002 Oct; 41(40):12032-42. PubMed ID: 12356303
[TBL] [Abstract][Full Text] [Related]
4. Mimicking enzyme evolution by generating new (betaalpha)8-barrels from (betaalpha)4-half-barrels.
Höcker B; Claren J; Sterner R
Proc Natl Acad Sci U S A; 2004 Nov; 101(47):16448-53. PubMed ID: 15539462
[TBL] [Abstract][Full Text] [Related]
5. Crystal structure of the yeast His6 enzyme suggests a reaction mechanism.
Quevillon-Cheruel S; Leulliot N; Graille M; Blondeau K; Janin J; van Tilbeurgh H
Protein Sci; 2006 Jun; 15(6):1516-21. PubMed ID: 16731983
[TBL] [Abstract][Full Text] [Related]
6. Simulations reveal the key role of Arg15 in the promiscuous activity in the HisA enzyme.
Dubey KD; Singh W
Org Biomol Chem; 2021 Dec; 19(48):10652-10661. PubMed ID: 34854451
[TBL] [Abstract][Full Text] [Related]
7. Occurrence of a putative ancient-like isomerase involved in histidine and tryptophan biosynthesis.
Barona-Gómez F; Hodgson DA
EMBO Rep; 2003 Mar; 4(3):296-300. PubMed ID: 12634849
[TBL] [Abstract][Full Text] [Related]
8. Evolution of substrate specificity in a recipient's enzyme following horizontal gene transfer.
Noda-García L; Camacho-Zarco AR; Medina-Ruíz S; Gaytán P; Carrillo-Tripp M; Fülöp V; Barona-Gómez F
Mol Biol Evol; 2013 Sep; 30(9):2024-34. PubMed ID: 23800623
[TBL] [Abstract][Full Text] [Related]
9. Identification and analysis of residues contained on beta --> alpha loops of the dual-substrate (beta alpha)8 phosphoribosyl isomerase A specific for its phosphoribosyl anthranilate isomerase activity.
Noda-García L; Camacho-Zarco AR; Verdel-Aranda K; Wright H; Soberón X; Fülöp V; Barona-Gómez F
Protein Sci; 2010 Mar; 19(3):535-43. PubMed ID: 20066665
[TBL] [Abstract][Full Text] [Related]
10. A sugar isomerization reaction established on various (βα)₈-barrel scaffolds is based on substrate-assisted catalysis.
Reisinger B; Bocola M; List F; Claren J; Rajendran C; Sterner R
Protein Eng Des Sel; 2012 Nov; 25(11):751-60. PubMed ID: 23109729
[TBL] [Abstract][Full Text] [Related]
11. Complex Loop Dynamics Underpin Activity, Specificity, and Evolvability in the (βα)
Romero-Rivera A; Corbella M; Parracino A; Patrick WM; Kamerlin SCL
JACS Au; 2022 Apr; 2(4):943-960. PubMed ID: 35557756
[TBL] [Abstract][Full Text] [Related]
12. Imidazole glycerol phosphate synthase: the glutamine amidotransferase in histidine biosynthesis.
Klem TJ; Davisson VJ
Biochemistry; 1993 May; 32(19):5177-86. PubMed ID: 8494895
[TBL] [Abstract][Full Text] [Related]
13. Insights into the evolution of enzyme substrate promiscuity after the discovery of (βα)₈ isomerase evolutionary intermediates from a diverse metagenome.
Noda-García L; Juárez-Vázquez AL; Ávila-Arcos MC; Verduzco-Castro EA; Montero-Morán G; Gaytán P; Carrillo-Tripp M; Barona-Gómez F
BMC Evol Biol; 2015 Jun; 15():107. PubMed ID: 26058375
[TBL] [Abstract][Full Text] [Related]
14. Substrate-induced changes in the ammonia channel for imidazole glycerol phosphate synthase.
Myers RS; Jensen JR; Deras IL; Smith JL; Davisson VJ
Biochemistry; 2003 Jun; 42(23):7013-22. PubMed ID: 12795596
[TBL] [Abstract][Full Text] [Related]
15. Toward understanding the mechanism of the complex cyclization reaction catalyzed by imidazole glycerolphosphate synthase: crystal structures of a ternary complex and the free enzyme.
Chaudhuri BN; Lange SC; Myers RS; Davisson VJ; Smith JL
Biochemistry; 2003 Jun; 42(23):7003-12. PubMed ID: 12795595
[TBL] [Abstract][Full Text] [Related]
16. Interconverting the catalytic activities of (betaalpha)(8)-barrel enzymes from different metabolic pathways: sequence requirements and molecular analysis.
Leopoldseder S; Claren J; Jürgens C; Sterner R
J Mol Biol; 2004 Apr; 337(4):871-9. PubMed ID: 15033357
[TBL] [Abstract][Full Text] [Related]
17. The structure/function relationship of a dual-substrate (betaalpha)8-isomerase.
Wright H; Noda-García L; Ochoa-Leyva A; Hodgson DA; Fülöp V; Barona-Gómez F
Biochem Biophys Res Commun; 2008 Jan; 365(1):16-21. PubMed ID: 17967415
[TBL] [Abstract][Full Text] [Related]
18. On the multiple functional roles of the active site histidine in catalysis and allosteric regulation of Escherichia coli glucosamine 6-phosphate deaminase.
Montero-Morán GM; Lara-González S; Alvarez-Añorve LI; Plumbridge JA; Calcagno ML
Biochemistry; 2001 Aug; 40(34):10187-96. PubMed ID: 11513596
[TBL] [Abstract][Full Text] [Related]
19. Structural studies of a hyperthermophilic thymidylate kinase enzyme reveal conformational substates along the reaction coordinate.
Biswas A; Shukla A; Chaudhary SK; Santhosh R; Jeyakanthan J; Sekar K
FEBS J; 2017 Aug; 284(15):2527-2544. PubMed ID: 28627020
[TBL] [Abstract][Full Text] [Related]
20. Directed evolution of (βα)(8)-barrel enzymes: establishing phosphoribosylanthranilate isomerisation activity on the scaffold of the tryptophan synthase α-subunit.
Evran S; Telefoncu A; Sterner R
Protein Eng Des Sel; 2012 Jun; 25(6):285-93. PubMed ID: 22490958
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
