BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

143 related articles for article (PubMed ID: 26296657)

  • 1. pVHL interacts with Ceramide kinase like (CERKL) protein and ubiquitinates it for oxygen dependent proteasomal degradation.
    Chen J; Liu F; Li H; Archacki S; Gao M; Liu Y; Liao S; Huang M; Wang J; Yu S; Li C; Tang Z; Liu M
    Cell Signal; 2015 Nov; 27(11):2314-23. PubMed ID: 26296657
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Overexpression of CERKL, a gene responsible for retinitis pigmentosa in humans, protects cells from apoptosis induced by oxidative stress.
    Tuson M; Garanto A; Gonzàlez-Duarte R; Marfany G
    Mol Vis; 2009; 15():168-80. PubMed ID: 19158957
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CERKL interacts with mitochondrial TRX2 and protects retinal cells from oxidative stress-induced apoptosis.
    Li C; Wang L; Zhang J; Huang M; Wong F; Liu X; Liu F; Cui X; Yang G; Chen J; Liu Y; Wang J; Liao S; Gao M; Hu X; Shu X; Wang Q; Yin Z; Tang Z; Liu M
    Biochim Biophys Acta; 2014 Jul; 1842(7):1121-9. PubMed ID: 24735978
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Exacerbated response to oxidative stress in the Retinitis Pigmentosa Cerkl
    García-Arroyo R; Domènech EB; Herrera-Úbeda C; Asensi MA; Núñez de Arenas C; Cuezva JM; Garcia-Fernàndez J; Pallardó FV; Mirra S; Marfany G
    Redox Biol; 2023 Oct; 66():102862. PubMed ID: 37660443
    [TBL] [Abstract][Full Text] [Related]  

  • 5. pVHL mediates K63-linked ubiquitination of IKKβ, leading to IKKβ inactivation.
    Wang Y; Zhao W; Gao Q; Fan L; Qin Y; Zhou H; Li M; Fang J
    Cancer Lett; 2016 Dec; 383(1):1-8. PubMed ID: 27693634
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tat-binding protein-1, a component of the 26S proteasome, contributes to the E3 ubiquitin ligase function of the von Hippel-Lindau protein.
    Corn PG; McDonald ER; Herman JG; El-Deiry WS
    Nat Genet; 2003 Nov; 35(3):229-37. PubMed ID: 14556007
    [TBL] [Abstract][Full Text] [Related]  

  • 7. pVHL mediates K63-linked ubiquitination of nCLU.
    Xue J; Lv DD; Jiao S; Zhao W; Li X; Sun H; Yan B; Fan L; Hu RG; Fang J
    PLoS One; 2012; 7(4):e35848. PubMed ID: 22532874
    [TBL] [Abstract][Full Text] [Related]  

  • 8. CERKL gene knockout disturbs photoreceptor outer segment phagocytosis and causes rod-cone dystrophy in zebrafish.
    Yu S; Li C; Biswas L; Hu X; Liu F; Reilly J; Liu X; Liu Y; Huang Y; Lu Z; Han S; Wang L; Yu Liu J; Jiang T; Shu X; Wong F; Tang Z; Liu M
    Hum Mol Genet; 2017 Jun; 26(12):2335-2345. PubMed ID: 28398482
    [TBL] [Abstract][Full Text] [Related]  

  • 9. WSB1 promotes tumor metastasis by inducing pVHL degradation.
    Kim JJ; Lee SB; Jang J; Yi SY; Kim SH; Han SA; Lee JM; Tong SY; Vincelette ND; Gao B; Yin P; Evans D; Choi DW; Qin B; Liu T; Zhang H; Deng M; Jen J; Zhang J; Wang L; Lou Z
    Genes Dev; 2015 Nov; 29(21):2244-57. PubMed ID: 26545811
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of an alternative mechanism of degradation of the hypoxia-inducible factor-1alpha.
    André H; Pereira TS
    J Biol Chem; 2008 Oct; 283(43):29375-84. PubMed ID: 18694926
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PKCzetaII is a target for degradation through the tumour suppressor protein pVHL.
    Iturrioz X; Parker PJ
    FEBS Lett; 2007 Apr; 581(7):1397-402. PubMed ID: 17350623
    [TBL] [Abstract][Full Text] [Related]  

  • 12. CERKL regulates autophagy via the NAD-dependent deacetylase SIRT1.
    Hu X; Lu Z; Yu S; Reilly J; Liu F; Jia D; Qin Y; Han S; Liu X; Qu Z; Lv Y; Li J; Huang Y; Jiang T; Jia H; Wang Q; Liu J; Shu X; Tang Z; Liu M
    Autophagy; 2019 Mar; 15(3):453-465. PubMed ID: 30205735
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of cyclin D1 and other novel targets for the von Hippel-Lindau tumor suppressor gene by expression array analysis and investigation of cyclin D1 genotype as a modifier in von Hippel-Lindau disease.
    Zatyka M; da Silva NF; Clifford SC; Morris MR; Wiesener MS; Eckardt KU; Houlston RS; Richards FM; Latif F; Maher ER
    Cancer Res; 2002 Jul; 62(13):3803-11. PubMed ID: 12097293
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis.
    Maxwell PH; Wiesener MS; Chang GW; Clifford SC; Vaux EC; Cockman ME; Wykoff CC; Pugh CW; Maher ER; Ratcliffe PJ
    Nature; 1999 May; 399(6733):271-5. PubMed ID: 10353251
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RHOBTB3 promotes proteasomal degradation of HIFα through facilitating hydroxylation and suppresses the Warburg effect.
    Zhang CS; Liu Q; Li M; Lin SY; Peng Y; Wu D; Li TY; Fu Q; Jia W; Wang X; Ma T; Zong Y; Cui J; Pu C; Lian G; Guo H; Ye Z; Lin SC
    Cell Res; 2015 Sep; 25(9):1025-42. PubMed ID: 26215701
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regulation of receptor for activated C kinase 1 protein by the von Hippel-Lindau tumor suppressor in IGF-I-induced renal carcinoma cell invasiveness.
    He X; Wang J; Messing EM; Wu G
    Oncogene; 2011 Feb; 30(5):535-47. PubMed ID: 20871634
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The von Hippel-Lindau tumor suppressor protein and Egl-9-Type proline hydroxylases regulate the large subunit of RNA polymerase II in response to oxidative stress.
    Mikhaylova O; Ignacak ML; Barankiewicz TJ; Harbaugh SV; Yi Y; Maxwell PH; Schneider M; Van Geyte K; Carmeliet P; Revelo MP; Wyder M; Greis KD; Meller J; Czyzyk-Krzeska MF
    Mol Cell Biol; 2008 Apr; 28(8):2701-17. PubMed ID: 18285459
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The pathway for IRP2 degradation involving 2-oxoglutarate-dependent oxygenase(s) does not require the E3 ubiquitin ligase activity of pVHL.
    Wang J; Pantopoulos K
    Biochim Biophys Acta; 2005 Mar; 1743(1-2):79-85. PubMed ID: 15777842
    [TBL] [Abstract][Full Text] [Related]  

  • 19. von Hippel-Lindau protein binds hyperphosphorylated large subunit of RNA polymerase II through a proline hydroxylation motif and targets it for ubiquitination.
    Kuznetsova AV; Meller J; Schnell PO; Nash JA; Ignacak ML; Sanchez Y; Conaway JW; Conaway RC; Czyzyk-Krzeska MF
    Proc Natl Acad Sci U S A; 2003 Mar; 100(5):2706-11. PubMed ID: 12604794
    [TBL] [Abstract][Full Text] [Related]  

  • 20. TET is targeted for proteasomal degradation by the PHD-pVHL pathway to reduce DNA hydroxymethylation.
    Fan S; Wang J; Yu G; Rong F; Zhang D; Xu C; Du J; Li Z; Ouyang G; Xiao W
    J Biol Chem; 2020 Nov; 295(48):16299-16313. PubMed ID: 32963106
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.