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2. Safety and activity of RRx-001 in patients with advanced cancer: a first-in-human, open-label, dose-escalation phase 1 study. Reid T; Oronsky B; Scicinski J; Scribner CL; Knox SJ; Ning S; Peehl DM; Korn R; Stirn M; Carter CA; Oronsky A; Taylor MJ; Fitch WL; Cabrales P; Kim MM; Burris HA; Lao CD; Abrouk NED; Fanger GR; Infante JR Lancet Oncol; 2015 Sep; 16(9):1133-1142. PubMed ID: 26296952 [TBL] [Abstract][Full Text] [Related]
3. RRx-001, an epigenetic-based radio- and chemosensitizer, has vascular normalizing effects on SCCVII and U87 tumors. Oronsky B; Scicinski J; Cabrales P; Minchinton A Clin Epigenetics; 2016; 8():53. PubMed ID: 27175220 [TBL] [Abstract][Full Text] [Related]
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5. The Development Of RRx-001, A Novel Nitric-Oxide-Mediated Epigenetically Active Anticancer Agent. Scicinski J; Fisher G; Carter C; Cho-Phan C; Kunz P; Ning S; Knox S; Oronsky B; Caroen S; Parker C; Fanger G; Reid T Redox Biol; 2015 Aug; 5():422. PubMed ID: 28162292 [TBL] [Abstract][Full Text] [Related]
6. Conversion of Platinum-Etoposide-Resistant to Sensitive SCLC after Treatment with the Epi-Immunotherapeutic RRx-001: A Case Report. Brzezniak C; Oronsky B; Scicinski J; Caroen S; Cabrales P; Dean Abrouk N; Kim MM; Brown JF; Reid TR; Larson C; Oronsky A; Day R; Degesys A; Carter CA Oncol Res Treat; 2016; 39(11):720-723. PubMed ID: 27855386 [TBL] [Abstract][Full Text] [Related]
10. Epigenetic effects of RRx-001: a possible unifying mechanism of anticancer activity. Zhao H; Ning S; Scicinski J; Oronsky B; Knox SJ; Peehl DM Oncotarget; 2015 Dec; 6(41):43172-81. PubMed ID: 26657731 [TBL] [Abstract][Full Text] [Related]
11. Epigenetic perspectives on cancer chemotherapy response. Liu MZ; McLeod HL; He FZ; Chen XP; Zhou HH; Shu Y; Zhang W Pharmacogenomics; 2014 Apr; 15(5):699-715. PubMed ID: 24798726 [TBL] [Abstract][Full Text] [Related]
12. Genetic discoveries propagate new epigenetic drugs. Garber K J Natl Cancer Inst; 2012 Feb; 104(3):174-6. PubMed ID: 22271768 [No Abstract] [Full Text] [Related]
13. Addressing the elephant in the room, therapeutic resistance in non-small cell lung cancer, with epigenetic therapies. Carter CA; Zeman K; Day RM; Richard P; Oronsky A; Oronsky N; Lybeck M; Scicinski J; Oronsky B Oncotarget; 2016 Jun; 7(26):40781-40791. PubMed ID: 27007055 [TBL] [Abstract][Full Text] [Related]
14. Marking off new territory in the search for anticancer compounds: epigenetic mechanisms add complexity and promise to cancer research efforts. Nelson B Cancer Cytopathol; 2012 Jun; 120(3):143-4. PubMed ID: 22692980 [No Abstract] [Full Text] [Related]
15. Epigenetic therapies reach main street. Bates SE Clin Cancer Res; 2009 Jun; 15(12):3917. PubMed ID: 19528089 [No Abstract] [Full Text] [Related]
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18. Zebularine: a candidate for epigenetic cancer therapy. Bradbury J Drug Discov Today; 2004 Nov; 9(21):906-7. PubMed ID: 15501719 [TBL] [Abstract][Full Text] [Related]
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