BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

210 related articles for article (PubMed ID: 26300302)

  • 1. Human Erythroid 5-Aminolevulinate Synthase Mutations Associated with X-Linked Protoporphyria Disrupt the Conformational Equilibrium and Enhance Product Release.
    Fratz EJ; Clayton J; Hunter GA; Ducamp S; Breydo L; Uversky VN; Deybach JC; Gouya L; Puy H; Ferreira GC
    Biochemistry; 2015 Sep; 54(36):5617-31. PubMed ID: 26300302
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Isoniazid inhibits human erythroid 5-aminolevulinate synthase: Molecular mechanism and tolerance study with four X-linked protoporphyria patients.
    Fratz-Berilla EJ; Breydo L; Gouya L; Puy H; Uversky VN; Ferreira GC
    Biochim Biophys Acta Mol Basis Dis; 2017 Feb; 1863(2):428-439. PubMed ID: 27838491
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Molecular and functional analysis of the C-terminal region of human erythroid-specific 5-aminolevulinic synthase associated with X-linked dominant protoporphyria (XLDPP).
    Ducamp S; Schneider-Yin X; de Rooij F; Clayton J; Fratz EJ; Rudd A; Ostapowicz G; Varigos G; Lefebvre T; Deybach JC; Gouya L; Wilson P; Ferreira GC; Minder EI; Puy H
    Hum Mol Genet; 2013 Apr; 22(7):1280-8. PubMed ID: 23263862
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Anti-Correlation between the Dynamics of the Active Site Loop and C-Terminal Tail in Relation to the Homodimer Asymmetry of the Mouse Erythroid 5-Aminolevulinate Synthase.
    Na I; Catena D; Kong MJ; Ferreira GC; Uversky VN
    Int J Mol Sci; 2018 Jun; 19(7):. PubMed ID: 29958424
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular expression and characterization of erythroid-specific 5-aminolevulinate synthase gain-of-function mutations causing X-linked protoporphyria.
    Bishop DF; Tchaikovskii V; Nazarenko I; Desnick RJ
    Mol Med; 2013 Mar; 19(1):18-25. PubMed ID: 23348515
    [TBL] [Abstract][Full Text] [Related]  

  • 6. X-linked sideroblastic anemia due to carboxyl-terminal ALAS2 mutations that cause loss of binding to the β-subunit of succinyl-CoA synthetase (SUCLA2).
    Bishop DF; Tchaikovskii V; Hoffbrand AV; Fraser ME; Margolis S
    J Biol Chem; 2012 Aug; 287(34):28943-55. PubMed ID: 22740690
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Asn-150 of Murine Erythroid 5-Aminolevulinate Synthase Modulates the Catalytic Balance between the Rates of the Reversible Reaction.
    Stojanovski BM; Ferreira GC
    J Biol Chem; 2015 Dec; 290(52):30750-61. PubMed ID: 26511319
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Human aminolevulinate synthase structure reveals a eukaryotic-specific autoinhibitory loop regulating substrate binding and product release.
    Bailey HJ; Bezerra GA; Marcero JR; Padhi S; Foster WR; Rembeza E; Roy A; Bishop DF; Desnick RJ; Bulusu G; Dailey HA; Yue WW
    Nat Commun; 2020 Jun; 11(1):2813. PubMed ID: 32499479
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Serine 254 enhances an induced fit mechanism in murine 5-aminolevulinate synthase.
    Lendrihas T; Hunter GA; Ferreira GC
    J Biol Chem; 2010 Jan; 285(5):3351-9. PubMed ID: 19917609
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Murine erythroid 5-aminolevulinate synthase: Adenosyl-binding site Lys221 modulates substrate binding and catalysis.
    Stojanovski BM; Ferreira GC
    FEBS Open Bio; 2015; 5():824-31. PubMed ID: 26605136
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Unstable reaction intermediates and hysteresis during the catalytic cycle of 5-aminolevulinate synthase: implications from using pseudo and alternate substrates and a promiscuous enzyme variant.
    Stojanovski BM; Hunter GA; Jahn M; Jahn D; Ferreira GC
    J Biol Chem; 2014 Aug; 289(33):22915-22925. PubMed ID: 24920668
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure of the Mitochondrial Aminolevulinic Acid Synthase, a Key Heme Biosynthetic Enzyme.
    Brown BL; Kardon JR; Sauer RT; Baker TA
    Structure; 2018 Apr; 26(4):580-589.e4. PubMed ID: 29551290
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 5-Aminolevulinate synthase catalysis: The catcher in heme biosynthesis.
    Stojanovski BM; Hunter GA; Na I; Uversky VN; Jiang RHY; Ferreira GC
    Mol Genet Metab; 2019 Nov; 128(3):178-189. PubMed ID: 31345668
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 5-aminolevulinate synthase: catalysis of the first step of heme biosynthesis.
    Hunter GA; Ferreira GC
    Cell Mol Biol (Noisy-le-grand); 2009 Feb; 55(1):102-10. PubMed ID: 19268008
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Expression of murine 5-aminolevulinate synthase variants causes protoporphyrin IX accumulation and light-induced mammalian cell death.
    Fratz EJ; Hunter GA; Ferreira GC
    PLoS One; 2014; 9(4):e93078. PubMed ID: 24718052
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Delta-aminolevulinic acid synthase 2 expression in combination with iron as modifiers of disease severity in erythropoietic protoporphyria.
    Barman-Aksözen J; Halloy F; Iyer PS; Schümperli D; Minder AE; Hall J; Minder EI; Schneider-Yin X
    Mol Genet Metab; 2019 Nov; 128(3):304-308. PubMed ID: 31076252
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structural basis for dysregulation of aminolevulinic acid synthase in human disease.
    Taylor JL; Brown BL
    J Biol Chem; 2022 Mar; 298(3):101643. PubMed ID: 35093382
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Transient state kinetic investigation of 5-aminolevulinate synthase reaction mechanism.
    Zhang J; Ferreira GC
    J Biol Chem; 2002 Nov; 277(47):44660-9. PubMed ID: 12191993
    [TBL] [Abstract][Full Text] [Related]  

  • 19. X-linked dominant protoporphyria: The first reported Japanese case.
    Ninomiya Y; Kokunai Y; Tanizaki H; Akasaka E; Nakano H; Moriwaki S
    J Dermatol; 2016 Apr; 43(4):414-8. PubMed ID: 26387792
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effect of 5-aminolevulinic acid on erythropoiesis: a preclinical in vitro characterization for the treatment of congenital sideroblastic anemia.
    Fujiwara T; Okamoto K; Niikuni R; Takahashi K; Okitsu Y; Fukuhara N; Onishi Y; Ishizawa K; Ichinohasama R; Nakamura Y; Nakajima M; Tanaka T; Harigae H
    Biochem Biophys Res Commun; 2014 Nov; 454(1):102-8. PubMed ID: 25450364
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.