BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

251 related articles for article (PubMed ID: 26305410)

  • 1. Cdc6 ATPase activity disengages Cdc6 from the pre-replicative complex to promote DNA replication.
    Chang F; Riera A; Evrin C; Sun J; Li H; Speck C; Weinreich M
    Elife; 2015 Aug; 4():. PubMed ID: 26305410
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Origin licensing requires ATP binding and hydrolysis by the MCM replicative helicase.
    Coster G; Frigola J; Beuron F; Morris EP; Diffley JF
    Mol Cell; 2014 Sep; 55(5):666-77. PubMed ID: 25087873
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In the absence of ATPase activity, pre-RC formation is blocked prior to MCM2-7 hexamer dimerization.
    Evrin C; Fernández-Cid A; Zech J; Herrera MC; Riera A; Clarke P; Brill S; Lurz R; Speck C
    Nucleic Acids Res; 2013 Mar; 41(5):3162-72. PubMed ID: 23376927
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural basis of Mcm2-7 replicative helicase loading by ORC-Cdc6 and Cdt1.
    Yuan Z; Riera A; Bai L; Sun J; Nandi S; Spanos C; Chen ZA; Barbon M; Rappsilber J; Stillman B; Speck C; Li H
    Nat Struct Mol Biol; 2017 Mar; 24(3):316-324. PubMed ID: 28191893
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cdc6 ATPase activity regulates ORC x Cdc6 stability and the selection of specific DNA sequences as origins of DNA replication.
    Speck C; Stillman B
    J Biol Chem; 2007 Apr; 282(16):11705-14. PubMed ID: 17314092
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sequential ATP hydrolysis by Cdc6 and ORC directs loading of the Mcm2-7 helicase.
    Randell JC; Bowers JL; Rodríguez HK; Bell SP
    Mol Cell; 2006 Jan; 21(1):29-39. PubMed ID: 16387651
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The ORC/Cdc6/MCM2-7 complex facilitates MCM2-7 dimerization during prereplicative complex formation.
    Evrin C; Fernández-Cid A; Riera A; Zech J; Clarke P; Herrera MC; Tognetti S; Lurz R; Speck C
    Nucleic Acids Res; 2014 Feb; 42(4):2257-69. PubMed ID: 24234446
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cdt1 stabilizes an open MCM ring for helicase loading.
    Frigola J; He J; Kinkelin K; Pye VE; Renault L; Douglas ME; Remus D; Cherepanov P; Costa A; Diffley JFX
    Nat Commun; 2017 Jun; 8():15720. PubMed ID: 28643783
    [TBL] [Abstract][Full Text] [Related]  

  • 9. An ORC/Cdc6/MCM2-7 complex is formed in a multistep reaction to serve as a platform for MCM double-hexamer assembly.
    Fernández-Cid A; Riera A; Tognetti S; Herrera MC; Samel S; Evrin C; Winkler C; Gardenal E; Uhle S; Speck C
    Mol Cell; 2013 May; 50(4):577-88. PubMed ID: 23603117
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Stabilisation of half MCM ring by Cdt1 during DNA insertion.
    Guerrero-Puigdevall M; Fernandez-Fuentes N; Frigola J
    Nat Commun; 2021 Mar; 12(1):1746. PubMed ID: 33741931
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A unique DNA entry gate serves for regulated loading of the eukaryotic replicative helicase MCM2-7 onto DNA.
    Samel SA; Fernández-Cid A; Sun J; Riera A; Tognetti S; Herrera MC; Li H; Speck C
    Genes Dev; 2014 Aug; 28(15):1653-66. PubMed ID: 25085418
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Replication origin-flanking roadblocks reveal origin-licensing dynamics and altered sequence dependence.
    Warner MD; Azmi IF; Kang S; Zhao Y; Bell SP
    J Biol Chem; 2017 Dec; 292(52):21417-21430. PubMed ID: 29074622
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6.
    Yuan Z; Schneider S; Dodd T; Riera A; Bai L; Yan C; Magdalou I; Ivanov I; Stillman B; Li H; Speck C
    Proc Natl Acad Sci U S A; 2020 Jul; 117(30):17747-17756. PubMed ID: 32669428
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dynamics of pre-replicative complex assembly.
    Tsakraklides V; Bell SP
    J Biol Chem; 2010 Mar; 285(13):9437-9443. PubMed ID: 20097898
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cryo-EM structure of a helicase loading intermediate containing ORC-Cdc6-Cdt1-MCM2-7 bound to DNA.
    Sun J; Evrin C; Samel SA; Fernández-Cid A; Riera A; Kawakami H; Stillman B; Speck C; Li H
    Nat Struct Mol Biol; 2013 Aug; 20(8):944-51. PubMed ID: 23851460
    [TBL] [Abstract][Full Text] [Related]  

  • 16. ATPase-dependent quality control of DNA replication origin licensing.
    Frigola J; Remus D; Mehanna A; Diffley JF
    Nature; 2013 Mar; 495(7441):339-43. PubMed ID: 23474987
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Biochemical analysis of components of the pre-replication complex of Archaeoglobus fulgidus.
    Grainge I; Scaife S; Wigley DB
    Nucleic Acids Res; 2003 Aug; 31(16):4888-98. PubMed ID: 12907732
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural and mechanistic insights into Mcm2-7 double-hexamer assembly and function.
    Sun J; Fernandez-Cid A; Riera A; Tognetti S; Yuan Z; Stillman B; Speck C; Li H
    Genes Dev; 2014 Oct; 28(20):2291-303. PubMed ID: 25319829
    [TBL] [Abstract][Full Text] [Related]  

  • 19. DNA replication origins retain mobile licensing proteins.
    Sánchez H; McCluskey K; van Laar T; van Veen E; Asscher FM; Solano B; Diffley JFX; Dekker NH
    Nat Commun; 2021 Mar; 12(1):1908. PubMed ID: 33772005
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Single-molecule studies of origin licensing reveal mechanisms ensuring bidirectional helicase loading.
    Ticau S; Friedman LJ; Ivica NA; Gelles J; Bell SP
    Cell; 2015 Apr; 161(3):513-525. PubMed ID: 25892223
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.