BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

42 related articles for article (PubMed ID: 26309122)

  • 1. Design, Synthesis, Molecular Modeling, and Biological Evaluation of Novel Amine-based Histone Deacetylase Inhibitors.
    Abdelkarim H; Neelarapu R; Madriaga A; Vaidya AS; Kastrati I; Karumudi B; Wang YT; Taha TY; Thatcher GRJ; Frasor J; Petukhov PA
    ChemMedChem; 2017 Dec; 12(24):2030-2043. PubMed ID: 29080240
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and structure-activity relationship of 3-hydroxypyridine-2-thione-based histone deacetylase inhibitors.
    Sodji QH; Patil V; Kornacki JR; Mrksich M; Oyelere AK
    J Med Chem; 2013 Dec; 56(24):9969-81. PubMed ID: 24304348
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Bifunctional conjugates with potent inhibitory activity towards cyclooxygenase and histone deacetylase.
    Raji I; Yadudu F; Janeira E; Fathi S; Szymczak L; Kornacki JR; Komatsu K; Li JD; Mrksich M; Oyelere AK
    Bioorg Med Chem; 2017 Feb; 25(3):1202-1218. PubMed ID: 28057407
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Benzothiazole derivatives as histone deacetylase inhibitors for the treatment of autosomal dominant polycystic kidney disease.
    Cao X; Fan Z; Xu L; Zhao W; Zhang H; Yang Y; Ren Y; Xiao Y; Zhou N; Yin L; Zhou X; Zhu X; Guo D
    Eur J Med Chem; 2024 May; 271():116428. PubMed ID: 38653068
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Lansoprazole as a potent HDAC2 inhibitor for treatment of colorectal cancer: An in-silico analysis and experimental validation.
    Khadempar S; Lotfi M; Haghiralsadat F; Saidijam M; Ghasemi N; Afshar S
    Comput Biol Med; 2023 Nov; 166():107518. PubMed ID: 37806058
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Leveraging a rationally designed veliparib-based anilide eliciting anti-leukemic effects for the design of pH-responsive polymer nanoformulation.
    Thakur A; Chu YH; Rao NV; Mathew J; Grewal AS; Prabakaran P; Guru S; Liou JP; Pan CH; Nepali K
    Eur J Med Chem; 2024 Jul; 273():116507. PubMed ID: 38776806
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery, optimization and biological activity evaluation of genipin derivatives as potential KRAS G12D inhibitors.
    Sun R; Hu Y; Liu X; Lin Y; Lv D; Li W; Fu L; Jiang F
    Bioorg Chem; 2024 Jul; 148():107460. PubMed ID: 38781668
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ring-opened tetrahydro-γ-carbolines display cytotoxicity and selectivity with histone deacetylase isoforms.
    Nepali K; Lee HY; Lai MJ; Ojha R; Wu TY; Wu GX; Chen MC; Liou JP
    Eur J Med Chem; 2017 Feb; 127():115-127. PubMed ID: 28038324
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Creation of a histone deacetylase 6 inhibitor and its biological effects [corrected].
    Lee JH; Yao Y; Mahendran A; Ngo L; Venta-Perez G; Choy ML; Breslow R; Marks PA
    Proc Natl Acad Sci U S A; 2015 Sep; 112(39):12005-10. PubMed ID: 26371309
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of Histone Deacetylase 6 Activity via S-Nitrosylation.
    Okuda K; Ito A; Uehara T
    Biol Pharm Bull; 2015; 38(9):1434-7. PubMed ID: 26328501
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel histone deacetylase inhibitor MPT0G009 induces cell apoptosis and synergistic anticancer activity with tumor necrosis factor-related apoptosis-inducing ligand against human hepatocellular carcinoma.
    Chen MC; Huang HH; Lai CY; Lin YJ; Liou JP; Lai MJ; Li YH; Teng CM; Yang CR
    Oncotarget; 2016 Jan; 7(1):402-17. PubMed ID: 26587975
    [TBL] [Abstract][Full Text] [Related]  

  • 12. HDAC6: A unique HDAC family member as a cancer target.
    Kaur S; Rajoria P; Chopra M
    Cell Oncol (Dordr); 2022 Oct; 45(5):779-829. PubMed ID: 36036883
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of HDAC6 and Its Selective Inhibitors in Gastrointestinal Cancer.
    Zhou B; Liu D; Tan Y
    Front Cell Dev Biol; 2021; 9():719390. PubMed ID: 34938729
    [TBL] [Abstract][Full Text] [Related]  

  • 14. HDAC6-an Emerging Target Against Chronic Myeloid Leukemia?
    Losson H; Schnekenburger M; Dicato M; Diederich M
    Cancers (Basel); 2020 Jan; 12(2):. PubMed ID: 32013157
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Off-target toxicity is a common mechanism of action of cancer drugs undergoing clinical trials.
    Lin A; Giuliano CJ; Palladino A; John KM; Abramowicz C; Yuan ML; Sausville EL; Lukow DA; Liu L; Chait AR; Galluzzo ZC; Tucker C; Sheltzer JM
    Sci Transl Med; 2019 Sep; 11(509):. PubMed ID: 31511426
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Histone deacetylase 6 is overexpressed and promotes tumor growth of colon cancer through regulation of the MAPK/ERK signal pathway.
    Zhang SL; Zhu HY; Zhou BY; Chu Y; Huo JR; Tan YY; Liu DL
    Onco Targets Ther; 2019; 12():2409-2419. PubMed ID: 31118659
    [No Abstract]   [Full Text] [Related]  

  • 17. Pyrimidinedione-mediated selective histone deacetylase 6 inhibitors with antitumor activity in colorectal cancer HCT116 cells.
    Liu YM; Lee HY; Lai MJ; Pan SL; Huang HL; Kuo FC; Chen MC; Liou JP
    Org Biomol Chem; 2015 Oct; 13(40):10226-35. PubMed ID: 26309122
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effect of C7-substitution of 1-arylsulfonyl-5-(N-hydroxyacrylamide)indolines on the selectivity towards a subclass of histone deacetylases.
    Lee HY; Wang LT; Li YH; Pan SL; Chen YL; Teng CM; Liou JP
    Org Biomol Chem; 2014 Nov; 12(44):8966-76. PubMed ID: 25277250
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis and biological evaluation of novel thioquinazolinone-based 2-aminobenzamide derivatives as potent histone deacetylase (HDAC) inhibitors.
    Cheng C; Yun F; He J; Ullah S; Yuan Q
    Eur J Med Chem; 2019 Jul; 173():185-202. PubMed ID: 31003060
    [TBL] [Abstract][Full Text] [Related]  

  • 20.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 3.