BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 26329580)

  • 1. Dissecting the signaling pathways that mediate cancer in PTEN and LKB1 double-knockout mice.
    Chen J; Zhang XD; Proud C
    Sci Signal; 2015 Sep; 8(392):pe1. PubMed ID: 26329580
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice.
    Huang X; Wullschleger S; Shpiro N; McGuire VA; Sakamoto K; Woods YL; McBurnie W; Fleming S; Alessi DR
    Biochem J; 2008 Jun; 412(2):211-21. PubMed ID: 18387000
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PI3K/Akt/mTOR signaling & its regulator tumour suppressor genes
    Makker A; Goel MM; Mahdi AA; Bhatia V; Das V; Agarwal A; Pandey A
    Indian J Med Res; 2016 May; 143(Supplement):S112-S119. PubMed ID: 27748285
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cancer therapy: staying current with AMPK.
    Fruman DA; Edinger AL
    Biochem J; 2008 Jun; 412(2):e3-5. PubMed ID: 18466113
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Fibronectin stimulates non-small cell lung carcinoma cell growth through activation of Akt/mammalian target of rapamycin/S6 kinase and inactivation of LKB1/AMP-activated protein kinase signal pathways.
    Han S; Khuri FR; Roman J
    Cancer Res; 2006 Jan; 66(1):315-23. PubMed ID: 16397245
    [TBL] [Abstract][Full Text] [Related]  

  • 6. AKT-mediated stabilization of histone methyltransferase WHSC1 promotes prostate cancer metastasis.
    Li N; Xue W; Yuan H; Dong B; Ding Y; Liu Y; Jiang M; Kan S; Sun T; Ren J; Pan Q; Li X; Zhang P; Hu G; Wang Y; Wang X; Li Q; Qin J
    J Clin Invest; 2017 Apr; 127(4):1284-1302. PubMed ID: 28319045
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast.
    Rodríguez-Escudero I; Roelants FM; Thorner J; Nombela C; Molina M; Cid VJ
    Biochem J; 2005 Sep; 390(Pt 2):613-23. PubMed ID: 15913452
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Akt and mTORC1 have different roles during liver tumorigenesis in mice.
    Kenerson HL; Yeh MM; Kazami M; Jiang X; Riehle KJ; McIntyre RL; Park JO; Kwon S; Campbell JS; Yeung RS
    Gastroenterology; 2013 May; 144(5):1055-65. PubMed ID: 23376645
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phosphatidylinositol 3-kinase signaling determines kidney size.
    Chen JK; Nagai K; Chen J; Plieth D; Hino M; Xu J; Sha F; Ikizler TA; Quarles CC; Threadgill DW; Neilson EG; Harris RC
    J Clin Invest; 2015 Jun; 125(6):2429-44. PubMed ID: 25985273
    [TBL] [Abstract][Full Text] [Related]  

  • 10. AMPK/TSC2/mTOR-signaling intermediates are not necessary for LKB1-mediated nuclear retention of PTEN tumor suppressor.
    Liu JL; Mao Z; Gallick GE; Yung WK
    Neuro Oncol; 2011 Feb; 13(2):184-94. PubMed ID: 21123367
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PTEN, more than the AKT pathway.
    Blanco-Aparicio C; Renner O; Leal JF; Carnero A
    Carcinogenesis; 2007 Jul; 28(7):1379-86. PubMed ID: 17341655
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Reactive nitrogen species induced by hyperglycemia suppresses Akt signaling and triggers apoptosis by upregulating phosphatase PTEN (phosphatase and tensin homologue deleted on chromosome 10) in an LKB1-dependent manner.
    Song P; Wu Y; Xu J; Xie Z; Dong Y; Zhang M; Zou MH
    Circulation; 2007 Oct; 116(14):1585-95. PubMed ID: 17875968
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Targeting the translational apparatus to improve leukemia therapy: roles of the PI3K/PTEN/Akt/mTOR pathway.
    Martelli AM; Evangelisti C; Chappell W; Abrams SL; Bäsecke J; Stivala F; Donia M; Fagone P; Nicoletti F; Libra M; Ruvolo V; Ruvolo P; Kempf CR; Steelman LS; McCubrey JA
    Leukemia; 2011 Jul; 25(7):1064-79. PubMed ID: 21436840
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Stromal liver kinase B1 [STK11] signaling loss induces oviductal adenomas and endometrial cancer by activating mammalian Target of Rapamycin Complex 1.
    Tanwar PS; Kaneko-Tarui T; Zhang L; Tanaka Y; Crum CP; Teixeira JM
    PLoS Genet; 2012; 8(8):e1002906. PubMed ID: 22916036
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Livers with constitutive mTORC1 activity resist steatosis independent of feedback suppression of Akt.
    Kenerson HL; Subramanian S; McIntyre R; Kazami M; Yeung RS
    PLoS One; 2015; 10(2):e0117000. PubMed ID: 25646773
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The PTEN/Akt pathway dictates the direct alphaVbeta3-dependent growth-inhibitory action of an active fragment of tumstatin in glioma cells in vitro and in vivo.
    Kawaguchi T; Yamashita Y; Kanamori M; Endersby R; Bankiewicz KS; Baker SJ; Bergers G; Pieper RO
    Cancer Res; 2006 Dec; 66(23):11331-40. PubMed ID: 17145879
    [TBL] [Abstract][Full Text] [Related]  

  • 17. TSC1/TSC2 inactivation inhibits AKT through mTORC1-dependent up-regulation of STAT3-PTEN cascade.
    Zha X; Hu Z; He S; Wang F; Shen H; Zhang H
    Cancer Lett; 2011 Dec; 313(2):211-7. PubMed ID: 22055460
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Growth hormone modulation of EGF-induced PI3K-Akt pathway in mice liver.
    Díaz ME; González L; Miquet JG; Martínez CS; Sotelo AI; Bartke A; Turyn D
    Cell Signal; 2012 Feb; 24(2):514-523. PubMed ID: 22019461
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effects of epidermal growth factor receptor and phosphatase and tensin homologue gene expression on the inhibition of U87MG glioblastoma cell proliferation induced by protein kinase inhibitors.
    Xing WJ; Zou Y; Han QL; Dong YC; Deng ZL; Lv XH; Jiang T; Ren H
    Clin Exp Pharmacol Physiol; 2013 Jan; 40(1):13-21. PubMed ID: 23110505
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A genetic mouse model of invasive endometrial cancer driven by concurrent loss of Pten and Lkb1 Is highly responsive to mTOR inhibition.
    Cheng H; Liu P; Zhang F; Xu E; Symonds L; Ohlson CE; Bronson RT; Maira SM; Di Tomaso E; Li J; Myers AP; Cantley LC; Mills GB; Zhao JJ
    Cancer Res; 2014 Jan; 74(1):15-23. PubMed ID: 24322983
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.