BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

211 related articles for article (PubMed ID: 26329788)

  • 21. Nimesulide and 4'-Hydroxynimesulide as Bile Acid Transporters Inhibitors Are Contributory Factors for Drug-Induced Cholestasis.
    Zhou L; Pang X; Jiang J; Zhong D; Chen X
    Drug Metab Dispos; 2017 May; 45(5):441-448. PubMed ID: 28202577
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Sandwich-Cultured Hepatocytes as a Tool to Study Drug Disposition and Drug-Induced Liver Injury.
    Yang K; Guo C; Woodhead JL; St Claire RL; Watkins PB; Siler SQ; Howell BA; Brouwer KLR
    J Pharm Sci; 2016 Feb; 105(2):443-459. PubMed ID: 26869411
    [TBL] [Abstract][Full Text] [Related]  

  • 23. High-Throughput Screening to Evaluate Inhibition of Bile Acid Transporters Using Human Hepatocytes Isolated From Chimeric Mice.
    Kohara H; Bajaj P; Yamanaka K; Miyawaki A; Harada K; Miyamoto K; Matsui T; Okai Y; Wagoner M; Shinozawa T
    Toxicol Sci; 2020 Feb; 173(2):347-361. PubMed ID: 31722436
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Drug-induced cholestasis detection in cryopreserved rat hepatocytes in sandwich culture.
    Oorts M; Richert L; Annaert P
    J Pharmacol Toxicol Methods; 2015; 73():63-71. PubMed ID: 25828992
    [TBL] [Abstract][Full Text] [Related]  

  • 25. In vitro bile acid-dependent hepatocyte toxicity assay system using human induced pluripotent stem cell-derived hepatocytes: Current status and disadvantages to overcome.
    Sakai Y; Iwao T; Susukida T; Nukaga T; Takemura A; Sekine S; Ito K; Matsunaga T
    Drug Metab Pharmacokinet; 2019 Aug; 34(4):264-271. PubMed ID: 31285099
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Both cholestatic and steatotic drugs trigger extensive alterations in the mRNA level of biliary transporters in rat hepatocytes: Application to develop new predictive biomarkers for early drug development.
    Donato MT; López-Riera M; Castell JV; Gómez-Lechón MJ; Jover R
    Toxicol Lett; 2016 Nov; 263():58-67. PubMed ID: 27765674
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Predictive Value of Cellular Accumulation of Hydrophobic Bile Acids As a Marker of Cholestatic Drug Potential.
    Burban A; Sharanek A; Humbert L; Eguether T; Guguen-Guillouzo C; Rainteau D; Guillouzo A
    Toxicol Sci; 2019 Apr; 168(2):474-485. PubMed ID: 30629237
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Critical Factors in the Assessment of Cholestatic Liver Injury In Vitro.
    Woolbright BL; Jaeschke H
    Methods Mol Biol; 2015; 1250():363-76. PubMed ID: 26272158
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Evaluation of hepatotoxic potential of drugs by inhibition of bile-acid transport in cultured primary human hepatocytes and intact rats.
    Kostrubsky VE; Strom SC; Hanson J; Urda E; Rose K; Burliegh J; Zocharski P; Cai H; Sinclair JF; Sahi J
    Toxicol Sci; 2003 Nov; 76(1):220-8. PubMed ID: 12944587
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Rat precision-cut liver slices predict drug-induced cholestatic injury.
    Starokozhko V; Greupink R; van de Broek P; Soliman N; Ghimire S; de Graaf IAM; Groothuis GMM
    Arch Toxicol; 2017 Oct; 91(10):3403-3413. PubMed ID: 28391356
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Toxicity and intracellular accumulation of bile acids in sandwich-cultured rat hepatocytes: role of glycine conjugates.
    Chatterjee S; Bijsmans IT; van Mil SW; Augustijns P; Annaert P
    Toxicol In Vitro; 2014 Mar; 28(2):218-30. PubMed ID: 24211540
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Validation of gene expression profiles from cholestatic hepatotoxicants in vitro against human in vivo cholestasis.
    Van den Hof WFPM; Coonen MLJ; van Herwijnen M; Brauers K; Jennen D; Olde Damink SWM; Schaap FG; Kleinjans JCS
    Toxicol In Vitro; 2017 Oct; 44():322-329. PubMed ID: 28778767
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Sandwich-cultured rat hepatocytes as an in vitro model to study canalicular transport alterations in cholestasis.
    Miszczuk GS; Barosso IR; Zucchetti AE; Boaglio AC; Pellegrino JM; Sánchez Pozzi EJ; Roma MG; Crocenzi FA
    Arch Toxicol; 2015 Jun; 89(6):979-90. PubMed ID: 24912783
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Beta-carotene prevents bile acid-induced cytotoxicity in the rat hepatocyte: Evidence for an antioxidant and anti-apoptotic role of beta-carotene in vitro.
    Gumpricht E; Dahl R; Devereaux MW; Sokol RJ
    Pediatr Res; 2004 May; 55(5):814-21. PubMed ID: 14764912
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Metabolomic analysis to discriminate drug-induced liver injury (DILI) phenotypes.
    Quintás G; Martínez-Sena T; Conde I; Pareja Ibars E; Kleinjans J; Castell JV
    Arch Toxicol; 2021 Sep; 95(9):3049-3062. PubMed ID: 34274980
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Comprehensive Evaluation of Bile Acid Homeostasis in Human Hepatocyte Co-Culture in the Presence of Troglitazone, Pioglitazone, and Acetylsalicylic Acid.
    Chang JH; Sangaraju D; Liu N; Jaochico A; Plise E
    Mol Pharm; 2019 Oct; 16(10):4230-4240. PubMed ID: 31509422
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Predicting drug-induced cholestasis: preclinical models.
    Petrov PD; Fernández-Murga ML; López-Riera M; Goméz-Lechón MJ; Castell JV; Jover R
    Expert Opin Drug Metab Toxicol; 2018 Jul; 14(7):721-738. PubMed ID: 29888962
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Investigations of free anthraquinones from rhubarb against alpha-naphthylisothiocyanate-induced cholestatic liver injury in rats.
    Zhao YL; Wang JB; Zhou GD; Shan LM; Xiao XH
    Basic Clin Pharmacol Toxicol; 2009 Jun; 104(6):463-9. PubMed ID: 19389047
    [TBL] [Abstract][Full Text] [Related]  

  • 39. The in silico identification of human bile salt export pump (ABCB11) inhibitors associated with cholestatic drug-induced liver injury.
    Xi L; Yao J; Wei Y; Wu X; Yao X; Liu H; Li S
    Mol Biosyst; 2017 Jan; 13(2):417-424. PubMed ID: 28092392
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Fasiglifam (TAK-875) Inhibits Hepatobiliary Transporters: A Possible Factor Contributing to Fasiglifam-Induced Liver Injury.
    Li X; Zhong K; Guo Z; Zhong D; Chen X
    Drug Metab Dispos; 2015 Nov; 43(11):1751-9. PubMed ID: 26276582
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.