These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

631 related articles for article (PubMed ID: 26331536)

  • 1. Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth.
    Zhu J; Sammons MA; Donahue G; Dou Z; Vedadi M; Getlik M; Barsyte-Lovejoy D; Al-awar R; Katona BW; Shilatifard A; Huang J; Hua X; Arrowsmith CH; Berger SL
    Nature; 2015 Sep; 525(7568):206-11. PubMed ID: 26331536
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differential effects of garcinol and curcumin on histone and p53 modifications in tumour cells.
    Collins HM; Abdelghany MK; Messmer M; Yue B; Deeves SE; Kindle KB; Mantelingu K; Aslam A; Winkler GS; Kundu TK; Heery DM
    BMC Cancer; 2013 Jan; 13():37. PubMed ID: 23356739
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Genomic and Epigenomic Features of Primary and Recurrent Hepatocellular Carcinomas.
    Ding X; He M; Chan AWH; Song QX; Sze SC; Chen H; Man MKH; Man K; Chan SL; Lai PBS; Wang X; Wong N
    Gastroenterology; 2019 Dec; 157(6):1630-1645.e6. PubMed ID: 31560893
    [TBL] [Abstract][Full Text] [Related]  

  • 4. p53 mutants induce transcription of NF-κB2 in H1299 cells through CBP and STAT binding on the NF-κB2 promoter and gain of function activity.
    Vaughan CA; Singh S; Windle B; Sankala HM; Graves PR; Andrew Yeudall W; Deb SP; Deb S
    Arch Biochem Biophys; 2012 Feb; 518(1):79-88. PubMed ID: 22198284
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting codon 158 p53-mutant cancers via the induction of p53 acetylation.
    Kong LR; Ong RW; Tan TZ; Mohamed Salleh NAB; Thangavelu M; Chan JV; Koh LYJ; Periyasamy G; Lau JA; Le TBU; Wang L; Lee M; Kannan S; Verma CS; Lim CM; Chng WJ; Lane DP; Venkitaraman A; Hung HT; Cheok CF; Goh BC
    Nat Commun; 2020 Apr; 11(1):2086. PubMed ID: 32350249
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Protein kinase Msk1 physically and functionally interacts with the KMT2A/MLL1 methyltransferase complex and contributes to the regulation of multiple target genes.
    Wiersma M; Bussiere M; Halsall JA; Turan N; Slany R; Turner BM; Nightingale KP
    Epigenetics Chromatin; 2016; 9():52. PubMed ID: 27895715
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mutant p53 regulates enhancer-associated H3K4 monomethylation through interactions with the methyltransferase MLL4.
    Rahnamoun H; Hong J; Sun Z; Lee J; Lu H; Lauberth SM
    J Biol Chem; 2018 Aug; 293(34):13234-13246. PubMed ID: 29954944
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Acquisition of aneuploidy drives mutant p53-associated gain-of-function phenotypes.
    Redman-Rivera LN; Shaver TM; Jin H; Marshall CB; Schafer JM; Sheng Q; Hongo RA; Beckermann KE; Wheeler FC; Lehmann BD; Pietenpol JA
    Nat Commun; 2021 Aug; 12(1):5184. PubMed ID: 34465782
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Histone acetylation and methylation: combinatorial players for transcriptional regulation.
    An W
    Subcell Biochem; 2007; 41():351-69. PubMed ID: 17484136
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Gain-of-function p53 activates multiple signaling pathways to induce oncogenicity in lung cancer cells.
    Vaughan CA; Singh S; Grossman SR; Windle B; Deb SP; Deb S
    Mol Oncol; 2017 Jun; 11(6):696-711. PubMed ID: 28423230
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Gain-of-function mutant p53 upregulates CXC chemokines and enhances cell migration.
    Yeudall WA; Vaughan CA; Miyazaki H; Ramamoorthy M; Choi MY; Chapman CG; Wang H; Black E; Bulysheva AA; Deb SP; Windle B; Deb S
    Carcinogenesis; 2012 Feb; 33(2):442-51. PubMed ID: 22114072
    [TBL] [Abstract][Full Text] [Related]  

  • 12. miR-193a targets MLL1 mRNA and drastically decreases MLL1 protein production: Ectopic expression of the miRNA aberrantly lowers H3K4me3 content of the chromatin and hampers cell proliferation and viability.
    Sengupta D; Deb M; Kar S; Parbin S; Pradhan N; Patra SK
    Gene; 2019 Jul; 705():22-35. PubMed ID: 31005612
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases.
    Barlev NA; Liu L; Chehab NH; Mansfield K; Harris KG; Halazonetis TD; Berger SL
    Mol Cell; 2001 Dec; 8(6):1243-54. PubMed ID: 11779500
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Histone methyltransferase MLL1 regulates MDR1 transcription and chemoresistance.
    Huo H; Magro PG; Pietsch EC; Patel BB; Scotto KW
    Cancer Res; 2010 Nov; 70(21):8726-35. PubMed ID: 20861184
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Crusade against Mutant p53: Does the COMPASS Point to the Holy Grail?
    Abraham CG; Espinosa JM
    Cancer Cell; 2015 Oct; 28(4):407-408. PubMed ID: 26461087
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Lysine methylation represses p53 activity in teratocarcinoma cancer cells.
    Zhu J; Dou Z; Sammons MA; Levine AJ; Berger SL
    Proc Natl Acad Sci U S A; 2016 Aug; 113(35):9822-7. PubMed ID: 27535933
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Transcriptional profiling reveals a subset of human breast tumors that retain wt TP53 but display mutant p53-associated features.
    Benor G; Fuks G; Chin SF; Rueda OM; Mukherjee S; Arandkar S; Aylon Y; Caldas C; Domany E; Oren M
    Mol Oncol; 2020 Aug; 14(8):1640-1652. PubMed ID: 32484602
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain.
    Weber LM; Jia Y; Stielow B; Gisselbrecht SS; Cao Y; Ren Y; Rohner I; King J; Rothman E; Fischer S; Simon C; Forné I; Nist A; Stiewe T; Bulyk ML; Wang Z; Liefke R
    Nucleic Acids Res; 2023 Jan; 51(2):574-594. PubMed ID: 36537216
    [TBL] [Abstract][Full Text] [Related]  

  • 19. COMPASS Ascending: Emerging clues regarding the roles of MLL3/KMT2C and MLL2/KMT2D proteins in cancer.
    Fagan RJ; Dingwall AK
    Cancer Lett; 2019 Aug; 458():56-65. PubMed ID: 31128216
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Histone modifying enzymes and cancer: going beyond histones.
    Zhang K; Dent SY
    J Cell Biochem; 2005 Dec; 96(6):1137-48. PubMed ID: 16173079
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 32.