These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
250 related articles for article (PubMed ID: 26334207)
1. Monitoring global growth of activity cliff information over time and assessing activity cliff frequencies and distributions. Stumpfe D; Bajorath J Future Med Chem; 2015 Aug; 7(12):1565-79. PubMed ID: 26334207 [TBL] [Abstract][Full Text] [Related]
2. Activity cliff clusters as a source of structure-activity relationship information. Dimova D; Stumpfe D; Hu Y; Bajorath J Expert Opin Drug Discov; 2015 May; 10(5):441-7. PubMed ID: 25715967 [TBL] [Abstract][Full Text] [Related]
3. Activity cliff networks for medicinal chemistry. Stumpfe D; Bajorath J Drug Dev Res; 2014 Aug; 75(5):291-8. PubMed ID: 25160069 [TBL] [Abstract][Full Text] [Related]
4. Do medicinal chemists learn from activity cliffs? A systematic evaluation of cliff progression in evolving compound data sets. Dimova D; Heikamp K; Stumpfe D; Bajorath J J Med Chem; 2013 Apr; 56(8):3339-45. PubMed ID: 23527828 [TBL] [Abstract][Full Text] [Related]
5. Method for the evaluation of structure-activity relationship information associated with coordinated activity cliffs. Dimova D; Stumpfe D; Bajorath J J Med Chem; 2014 Aug; 57(15):6553-63. PubMed ID: 25014781 [TBL] [Abstract][Full Text] [Related]
6. From activity cliffs to activity ridges: informative data structures for SAR analysis. Vogt M; Huang Y; Bajorath J J Chem Inf Model; 2011 Aug; 51(8):1848-56. PubMed ID: 21761918 [TBL] [Abstract][Full Text] [Related]
7. Simplified activity cliff network representations with high interpretability and immediate access to SAR information. Hu H; Bajorath J J Comput Aided Mol Des; 2020 Sep; 34(9):943-952. PubMed ID: 32500478 [TBL] [Abstract][Full Text] [Related]
10. Composition and topology of activity cliff clusters formed by bioactive compounds. Stumpfe D; Dimova D; Bajorath J J Chem Inf Model; 2014 Feb; 54(2):451-61. PubMed ID: 24437577 [TBL] [Abstract][Full Text] [Related]
11. Extraction of SAR information from activity cliff clusters via matching molecular series. Dimova D; Bajorath J Eur J Med Chem; 2014 Nov; 87():454-60. PubMed ID: 25282268 [TBL] [Abstract][Full Text] [Related]
12. Introducing a new category of activity cliffs with chemical modifications at multiple sites and rationalizing contributions of individual substitutions. Stumpfe D; Hu H; Bajorath J Bioorg Med Chem; 2019 Aug; 27(16):3605-3612. PubMed ID: 31272836 [TBL] [Abstract][Full Text] [Related]
14. Assessing the confidence level of public domain compound activity data and the impact of alternative potency measurements on SAR analysis. Stumpfe D; Bajorath J J Chem Inf Model; 2011 Dec; 51(12):3131-7. PubMed ID: 22059677 [TBL] [Abstract][Full Text] [Related]
15. Computational method for the identification of third generation activity cliffs. Stumpfe D; Hu H; Bajorath J MethodsX; 2020; 7():100793. PubMed ID: 31993342 [TBL] [Abstract][Full Text] [Related]
16. Modeling of activity landscapes for drug discovery. Bajorath J Expert Opin Drug Discov; 2012 Jun; 7(6):463-73. PubMed ID: 22475223 [TBL] [Abstract][Full Text] [Related]
17. Evolution of the activity cliff concept for structure-activity relationship analysis and drug discovery. Bajorath J Future Med Chem; 2014 Sep; 6(14):1545-9. PubMed ID: 25367389 [No Abstract] [Full Text] [Related]
18. Second-generation activity cliffs identified on the basis of target set-dependent potency difference criteria. Hu H; Stumpfe D; Bajorath J Future Med Chem; 2019 Mar; 11(5):379-394. PubMed ID: 30887828 [TBL] [Abstract][Full Text] [Related]
19. Systematic assessment of coordinated activity cliffs formed by kinase inhibitors and detailed characterization of activity cliff clusters and associated SAR information. Dimova D; Stumpfe D; Bajorath J Eur J Med Chem; 2015 Jan; 90():414-27. PubMed ID: 25461890 [TBL] [Abstract][Full Text] [Related]
20. Activity profile relationships between structurally similar promiscuous compounds. Hu Y; Bajorath J Eur J Med Chem; 2013 Nov; 69():393-8. PubMed ID: 24077530 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]