These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

163 related articles for article (PubMed ID: 26340537)

  • 1. Functional Impact of 14 Single Nucleotide Polymorphisms Causing Missense Mutations of Human α7 Nicotinic Receptor.
    Zhang Q; Du Y; Zhang J; Xu X; Xue F; Guo C; Huang Y; Lukas RJ; Chang Y
    PLoS One; 2015; 10(9):e0137588. PubMed ID: 26340537
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Distinct profiles of alpha7 nAChR positive allosteric modulation revealed by structurally diverse chemotypes.
    Grønlien JH; Håkerud M; Ween H; Thorin-Hagene K; Briggs CA; Gopalakrishnan M; Malysz J
    Mol Pharmacol; 2007 Sep; 72(3):715-24. PubMed ID: 17565004
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Allosteric Agonism of
    Gulsevin A; Papke RL; Stokes C; Garai S; Thakur GA; Quadri M; Horenstein NA
    Mol Pharmacol; 2019 Jun; 95(6):606-614. PubMed ID: 30944209
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterization.
    Hurst RS; Hajós M; Raggenbass M; Wall TM; Higdon NR; Lawson JA; Rutherford-Root KL; Berkenpas MB; Hoffmann WE; Piotrowski DW; Groppi VE; Allaman G; Ogier R; Bertrand S; Bertrand D; Arneric SP
    J Neurosci; 2005 Apr; 25(17):4396-405. PubMed ID: 15858066
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Activation of α7 nicotinic receptors by orthosteric and allosteric agonists: influence on single-channel kinetics and conductance.
    Pałczyńska MM; Jindrichova M; Gibb AJ; Millar NS
    Mol Pharmacol; 2012 Nov; 82(5):910-7. PubMed ID: 22874415
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Competitive binding at a nicotinic receptor transmembrane site of two α7-selective positive allosteric modulators with differing effects on agonist-evoked desensitization.
    Collins T; Young GT; Millar NS
    Neuropharmacology; 2011 Dec; 61(8):1306-13. PubMed ID: 21820451
    [TBL] [Abstract][Full Text] [Related]  

  • 7. An Unaltered Orthosteric Site and a Network of Long-Range Allosteric Interactions for PNU-120596 in α7 Nicotinic Acetylcholine Receptors.
    Marotta CB; Lester HA; Dougherty DA
    Chem Biol; 2015 Aug; 22(8):1063-73. PubMed ID: 26211363
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Agonist activation of alpha7 nicotinic acetylcholine receptors via an allosteric transmembrane site.
    Gill JK; Savolainen M; Young GT; Zwart R; Sher E; Millar NS
    Proc Natl Acad Sci U S A; 2011 Apr; 108(14):5867-72. PubMed ID: 21436053
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The activity of GAT107, an allosteric activator and positive modulator of α7 nicotinic acetylcholine receptors (nAChR), is regulated by aromatic amino acids that span the subunit interface.
    Papke RL; Horenstein NA; Kulkarni AR; Stokes C; Corrie LW; Maeng CY; Thakur GA
    J Biol Chem; 2014 Feb; 289(7):4515-31. PubMed ID: 24362025
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Critical Molecular Determinants of α7 Nicotinic Acetylcholine Receptor Allosteric Activation: SEPARATION OF DIRECT ALLOSTERIC ACTIVATION AND POSITIVE ALLOSTERIC MODULATION.
    Horenstein NA; Papke RL; Kulkarni AR; Chaturbhuj GU; Stokes C; Manther K; Thakur GA
    J Biol Chem; 2016 Mar; 291(10):5049-67. PubMed ID: 26742843
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PNU-120596, a positive allosteric modulator of mammalian α7 nicotinic acetylcholine receptor, is a negative modulator of ligand-gated chloride-selective channels of the gastropod Lymnaea stagnalis.
    Vulfius CA; Lebedev DS; Kryukova EV; Kudryavtsev DS; Kolbaev SN; Utkin YN; Tsetlin VI
    J Neurochem; 2020 Nov; 155(3):274-284. PubMed ID: 32248535
    [TBL] [Abstract][Full Text] [Related]  

  • 12. An allosteric modulator of alpha7 nicotinic receptors, N-(5-Chloro-2,4-dimethoxyphenyl)-N'-(5-methyl-3-isoxazolyl)-urea (PNU-120596), causes conformational changes in the extracellular ligand binding domain similar to those caused by acetylcholine.
    Barron SC; McLaughlin JT; See JA; Richards VL; Rosenberg RL
    Mol Pharmacol; 2009 Aug; 76(2):253-63. PubMed ID: 19411608
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mode of action of the positive modulator PNU-120596 on α7 nicotinic acetylcholine receptors.
    Szabo AK; Pesti K; Mike A; Vizi ES
    Neuropharmacology; 2014 Jun; 81():42-54. PubMed ID: 24486377
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Electrophysiological investigation of the effect of structurally different bispyridinium non-oxime compounds on human α7-nicotinic acetylcholine receptor activity-An in vitro structure-activity analysis.
    Scheffel C; Niessen KV; Rappenglück S; Wanner KT; Thiermann H; Worek F; Seeger T
    Toxicol Lett; 2018 Sep; 293():157-166. PubMed ID: 29191791
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Stable desensitization of α
    Pismataro MC; Horenstein NA; Stokes C; Dallanoce C; Thakur GA; Papke RL
    Eur J Pharmacol; 2021 Aug; 905():174179. PubMed ID: 34004208
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Evaluation of alpha7 nicotinic acetylcholine receptor agonists and positive allosteric modulators using the parallel oocyte electrophysiology test station.
    Malysz J; Grønlien JH; Timmermann DB; Håkerud M; Thorin-Hagene K; Ween H; Trumbull JD; Xiong Y; Briggs CA; Ahring PK; Dyhring T; Gopalakrishnan M
    Assay Drug Dev Technol; 2009 Aug; 7(4):374-90. PubMed ID: 19689206
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Development of Automated Patch Clamp Assay for Evaluation of α7 Nicotinic Acetylcholine Receptor Agonists in Automated QPatch-16.
    Hao Y; Tang J; Wang K
    Assay Drug Dev Technol; 2015 Apr; 13(3):174-84. PubMed ID: 25880723
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis, Pharmacological Characterization, and Structure-Activity Relationships of Noncanonical Selective Agonists for α7 nAChRs.
    Camacho-Hernandez GA; Stokes C; Duggan BM; Kaczanowska K; Brandao-Araiza S; Doan L; Papke RL; Taylor P
    J Med Chem; 2019 Nov; 62(22):10376-10390. PubMed ID: 31675224
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In vitro pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107.
    Malysz J; Anderson DJ; Grønlien JH; Ji J; Bunnelle WH; Håkerud M; Thorin-Hagene K; Ween H; Helfrich R; Hu M; Gubbins E; Gopalakrishnan S; Puttfarcken PS; Briggs CA; Li J; Meyer MD; Dyhring T; Ahring PK; Nielsen EØ; Peters D; Timmermann DB; Gopalakrishnan M
    J Pharmacol Exp Ther; 2010 Sep; 334(3):863-74. PubMed ID: 20504915
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Diversity of Nicotinic Acetylcholine Receptor Positive Allosteric Modulators Revealed by Mutagenesis and a Revised Structural Model.
    Newcombe J; Chatzidaki A; Sheppard TD; Topf M; Millar NS
    Mol Pharmacol; 2018 Feb; 93(2):128-140. PubMed ID: 29196491
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.