173 related articles for article (PubMed ID: 26340601)
1. Recent Update on Human Lactate Dehydrogenase Enzyme 5 (hLDH5) Inhibitors: A Promising Approach for Cancer Chemotherapy.
Rani R; Kumar V
J Med Chem; 2016 Jan; 59(2):487-96. PubMed ID: 26340601
[TBL] [Abstract][Full Text] [Related]
2. Targeting cancer metabolism to develop human lactate dehydrogenase (hLDH)5 inhibitors.
Zhang SL; He Y; Tam KY
Drug Discov Today; 2018 Jul; 23(7):1407-1415. PubMed ID: 29750903
[TBL] [Abstract][Full Text] [Related]
3. Three-Dimensional Analysis of the Interactions between hLDH5 and Its Inhibitors.
Poli G; Granchi C; Aissaoui M; Minutolo F; Tuccinardi T
Molecules; 2017 Dec; 22(12):. PubMed ID: 29236080
[TBL] [Abstract][Full Text] [Related]
4. Small-molecule inhibitors of human LDH5.
Granchi C; Paterni I; Rani R; Minutolo F
Future Med Chem; 2013 Oct; 5(16):1967-91. PubMed ID: 24175747
[TBL] [Abstract][Full Text] [Related]
5. N-Hydroxyindole-based inhibitors of lactate dehydrogenase against cancer cell proliferation.
Granchi C; Roy S; De Simone A; Salvetti I; Tuccinardi T; Martinelli A; Macchia M; Lanza M; Betti L; Giannaccini G; Lucacchini A; Giovannetti E; Sciarrillo R; Peters GJ; Minutolo F
Eur J Med Chem; 2011 Nov; 46(11):5398-407. PubMed ID: 21944286
[TBL] [Abstract][Full Text] [Related]
6. When will small molecule lactate dehydrogenase inhibitors realize their potential in the cancer clinic?
Rani R; Kumar V
Future Med Chem; 2017 Jul; 9(11):1113-1115. PubMed ID: 28722474
[No Abstract] [Full Text] [Related]
7. A Virtual Screening Study for Lactate Dehydrogenase 5 Inhibitors by Using a Pharmacophore-based Approach.
Tuccinardi T; Poli G; Corchia I; Granchi C; Lapillo M; Macchia M; Minutolo F; Ortore G; Martinelli A
Mol Inform; 2016 Sep; 35(8-9):434-9. PubMed ID: 27546047
[TBL] [Abstract][Full Text] [Related]
8. Computer-aided discovery and biological characterization of human lactate dehydrogenase 5 inhibitors with anti-osteosarcoma activity.
Cao W; Fang L; Teng S; Chen H; Wang Z
Bioorg Med Chem Lett; 2018 Jul; 28(13):2229-2233. PubMed ID: 29861142
[TBL] [Abstract][Full Text] [Related]
9. Discovery of N-hydroxyindole-based inhibitors of human lactate dehydrogenase isoform A (LDH-A) as starvation agents against cancer cells.
Granchi C; Roy S; Giacomelli C; Macchia M; Tuccinardi T; Martinelli A; Lanza M; Betti L; Giannaccini G; Lucacchini A; Funel N; León LG; Giovannetti E; Peters GJ; Palchaudhuri R; Calvaresi EC; Hergenrother PJ; Minutolo F
J Med Chem; 2011 Mar; 54(6):1599-612. PubMed ID: 21332213
[TBL] [Abstract][Full Text] [Related]
10. Structures of lactate dehydrogenase A (LDHA) in apo, ternary and inhibitor-bound forms.
Kolappan S; Shen DL; Mosi R; Sun J; McEachern EJ; Vocadlo DJ; Craig L
Acta Crystallogr D Biol Crystallogr; 2015 Feb; 71(Pt 2):185-95. PubMed ID: 25664730
[TBL] [Abstract][Full Text] [Related]
11. Discovery of human lactate dehydrogenase 5 inhibitors (hLDH5) with anti-lung cancer activity through an in silico method and biological validation.
He S; Wang Q
Bioorg Med Chem Lett; 2019 Sep; 29(17):2459-2463. PubMed ID: 31345633
[TBL] [Abstract][Full Text] [Related]
12. Targeting glycolysis: a fragment based approach towards bifunctional inhibitors of hLDH-5.
Moorhouse AD; Spiteri C; Sharma P; Zloh M; Moses JE
Chem Commun (Camb); 2011 Jan; 47(1):230-2. PubMed ID: 20676418
[TBL] [Abstract][Full Text] [Related]
13. Identification of a potent inhibitor targeting human lactate dehydrogenase A and its metabolic modulation for cancer cell line.
Chen CY; Feng Y; Chen JY; Deng H
Bioorg Med Chem Lett; 2016 Jan; 26(1):72-5. PubMed ID: 26597536
[TBL] [Abstract][Full Text] [Related]
14. Identification of N-acylhydrazone derivatives as novel lactate dehydrogenase A inhibitors.
Rupiani S; Buonfiglio R; Manerba M; Di Ianni L; Vettraino M; Giacomini E; Masetti M; Falchi F; Di Stefano G; Roberti M; Recanatini M
Eur J Med Chem; 2015 Aug; 101():63-70. PubMed ID: 26114812
[TBL] [Abstract][Full Text] [Related]
15. Dual targeting of the Warburg effect with a glucose-conjugated lactate dehydrogenase inhibitor.
Calvaresi EC; Granchi C; Tuccinardi T; Di Bussolo V; Huigens RW; Lee HY; Palchaudhuri R; Macchia M; Martinelli A; Minutolo F; Hergenrother PJ
Chembiochem; 2013 Nov; 14(17):2263-7. PubMed ID: 24174263
[TBL] [Abstract][Full Text] [Related]
16. Inhibitors of lactate dehydrogenase isoforms and their therapeutic potentials.
Granchi C; Bertini S; Macchia M; Minutolo F
Curr Med Chem; 2010; 17(7):672-97. PubMed ID: 20088761
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and initial screening of lactate dehydrogenase inhibitor activity of 1,3-benzodioxole derivatives.
Annas D; Cheon SY; Yusuf M; Bae SJ; Ha KT; Park KH
Sci Rep; 2020 Nov; 10(1):19889. PubMed ID: 33199724
[TBL] [Abstract][Full Text] [Related]
18. Development and validation of a docking-based virtual screening platform for the identification of new lactate dehydrogenase inhibitors.
Granchi C; Capecchi A; Del Frate G; Martinelli A; Macchia M; Minutolo F; Tuccinardi T
Molecules; 2015 May; 20(5):8772-90. PubMed ID: 25988609
[TBL] [Abstract][Full Text] [Related]
19. Inhibition of lactate dehydrogenase activity as an approach to cancer therapy.
Fiume L; Manerba M; Vettraino M; Di Stefano G
Future Med Chem; 2014 Mar; 6(4):429-45. PubMed ID: 24635523
[TBL] [Abstract][Full Text] [Related]
20. Label-free high-throughput assays to screen and characterize novel lactate dehydrogenase inhibitors.
Vanderporten E; Frick L; Turincio R; Thana P; Lamarr W; Liu Y
Anal Biochem; 2013 Oct; 441(2):115-22. PubMed ID: 23871998
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
