380 related articles for article (PubMed ID: 26340951)
1. Investigating the Degradation Behaviors of a Therapeutic Monoclonal Antibody Associated with pH and Buffer Species.
Zheng S; Qiu D; Adams M; Li J; Mantri RV; Gandhi R
AAPS PharmSciTech; 2017 Jan; 18(1):42-48. PubMed ID: 26340951
[TBL] [Abstract][Full Text] [Related]
2. Relation of Colloidal and Conformational Stabilities to Aggregate Formation in a Monoclonal Antibody.
Oyama H; Koga H; Tadokoro T; Maenaka K; Shiota A; Yokoyama M; Noda M; Torisu T; Uchiyama S
J Pharm Sci; 2020 Jan; 109(1):308-315. PubMed ID: 31669120
[TBL] [Abstract][Full Text] [Related]
3. Identification and characterization of monoclonal antibody fragments cleaved at the complementarity determining region using orthogonal analytical methods.
Li W; Yang B; Zhou D; Xu J; Li W; Suen WC
J Chromatogr B Analyt Technol Biomed Life Sci; 2017 Mar; 1048():121-129. PubMed ID: 28242491
[TBL] [Abstract][Full Text] [Related]
4. High throughput thermostability screening of monoclonal antibody formulations.
He F; Hogan S; Latypov RF; Narhi LO; Razinkov VI
J Pharm Sci; 2010 Apr; 99(4):1707-20. PubMed ID: 19780136
[TBL] [Abstract][Full Text] [Related]
5. Understanding the Increased Aggregation Propensity of a Light-Exposed IgG1 Monoclonal Antibody Using Hydrogen Exchange Mass Spectrometry, Biophysical Characterization, and Structural Analysis.
Bommana R; Chai Q; Schöneich C; Weiss WF; Majumdar R
J Pharm Sci; 2018 Jun; 107(6):1498-1511. PubMed ID: 29408480
[TBL] [Abstract][Full Text] [Related]
6. Evaluation of Hydrogen Exchange Mass Spectrometry as a Stability-Indicating Method for Formulation Excipient Screening for an IgG4 Monoclonal Antibody.
Toth RT; Pace SE; Mills BJ; Joshi SB; Esfandiary R; Middaugh CR; Weis DD; Volkin DB
J Pharm Sci; 2018 Apr; 107(4):1009-1019. PubMed ID: 29269271
[TBL] [Abstract][Full Text] [Related]
7. Mapping the mAb Aggregation Propensity Using Self-Interaction Chromatography as a Screening Tool.
Hedberg SHM; Lee D; Mishra Y; Haigh JM; Williams DR
Anal Chem; 2018 Mar; 90(6):3878-3885. PubMed ID: 29446917
[TBL] [Abstract][Full Text] [Related]
8. A comparison of biophysical characterization techniques in predicting monoclonal antibody stability.
Thiagarajan G; Semple A; James JK; Cheung JK; Shameem M
MAbs; 2016; 8(6):1088-97. PubMed ID: 27210456
[TBL] [Abstract][Full Text] [Related]
9. Kinetics and Characterization of Non-enzymatic Fragmentation of Monoclonal Antibody Therapeutics.
Ravuluri S; Bansal R; Chhabra N; Rathore AS
Pharm Res; 2018 May; 35(7):142. PubMed ID: 29761239
[TBL] [Abstract][Full Text] [Related]
10. Correlations between changes in conformational dynamics and physical stability in a mutant IgG1 mAb engineered for extended serum half-life.
Majumdar R; Esfandiary R; Bishop SM; Samra HS; Middaugh CR; Volkin DB; Weis DD
MAbs; 2015; 7(1):84-95. PubMed ID: 25524268
[TBL] [Abstract][Full Text] [Related]
11. Unfolding and aggregation of monoclonal antibodies on cation exchange columns: effects of resin type, load buffer, and protein stability.
Guo J; Carta G
J Chromatogr A; 2015 Apr; 1388():184-94. PubMed ID: 25739785
[TBL] [Abstract][Full Text] [Related]
12. Acetate- and Citrate-Specific Ion Effects on Unfolding and Temperature-Dependent Aggregation Rates of Anti-Streptavidin IgG1.
Barnett GV; Razinkov VI; Kerwin BA; Hillsley A; Roberts CJ
J Pharm Sci; 2016 Mar; 105(3):1066-73. PubMed ID: 26886346
[TBL] [Abstract][Full Text] [Related]
13. Stability of monoclonal antibodies at high-concentration: head-to-head comparison of the IgG1 and IgG4 subclass.
Neergaard MS; Nielsen AD; Parshad H; Van De Weert M
J Pharm Sci; 2014 Jan; 103(1):115-27. PubMed ID: 24282022
[TBL] [Abstract][Full Text] [Related]
14. Effect of buffer species on the unfolding and the aggregation of humanized IgG.
Kameoka D; Masuzaki E; Ueda T; Imoto T
J Biochem; 2007 Sep; 142(3):383-91. PubMed ID: 17646171
[TBL] [Abstract][Full Text] [Related]
15. Examination of thermal unfolding and aggregation profiles of a series of developable therapeutic monoclonal antibodies.
Brader ML; Estey T; Bai S; Alston RW; Lucas KK; Lantz S; Landsman P; Maloney KM
Mol Pharm; 2015 Apr; 12(4):1005-17. PubMed ID: 25687223
[TBL] [Abstract][Full Text] [Related]
16. Effects of pH and buffer concentration on the thermal stability of etanercept using DSC and DLS.
Kim NA; An IB; Lim DG; Lim JY; Lee SY; Shim WS; Kang NG; Jeong SH
Biol Pharm Bull; 2014; 37(5):808-16. PubMed ID: 24790003
[TBL] [Abstract][Full Text] [Related]
17. Effects of acid exposure on the conformation, stability, and aggregation of monoclonal antibodies.
Ejima D; Tsumoto K; Fukada H; Yumioka R; Nagase K; Arakawa T; Philo JS
Proteins; 2007 Mar; 66(4):954-62. PubMed ID: 17154421
[TBL] [Abstract][Full Text] [Related]
18. High Throughput Prediction Approach for Monoclonal Antibody Aggregation at High Concentration.
Zidar M; Šušterič A; Ravnik M; Kuzman D
Pharm Res; 2017 Sep; 34(9):1831-1839. PubMed ID: 28593474
[TBL] [Abstract][Full Text] [Related]
19. Influence of pH, buffer species, and storage temperature on physicochemical stability of a humanized monoclonal antibody LA298.
Zheng JY; Janis LJ
Int J Pharm; 2006 Feb; 308(1-2):46-51. PubMed ID: 16316730
[TBL] [Abstract][Full Text] [Related]
20. Effects of Protein Conformation, Apparent Solubility, and Protein-Protein Interactions on the Rates and Mechanisms of Aggregation for an IgG1Monoclonal Antibody.
Kalonia C; Toprani V; Toth R; Wahome N; Gabel I; Middaugh CR; Volkin DB
J Phys Chem B; 2016 Jul; 120(29):7062-75. PubMed ID: 27380437
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]