191 related articles for article (PubMed ID: 26342260)
1. Development and characterization of K562 cell clones expressing BCL11A-XL: Decreased hemoglobin production with fetal hemoglobin inducers and its rescue with mithramycin.
Finotti A; Gasparello J; Breveglieri G; Cosenza LC; Montagner G; Bresciani A; Altamura S; Bianchi N; Martini E; Gallerani E; Borgatti M; Gambari R
Exp Hematol; 2015 Dec; 43(12):1062-1071.e3. PubMed ID: 26342260
[TBL] [Abstract][Full Text] [Related]
2. Effects of Mithramycin on BCL11A Gene Expression and on the Interaction of the BCL11A Transcriptional Complex to γ-Globin Gene Promoter Sequences.
Finotti A; Gasparello J; Zuccato C; Cosenza LC; Fabbri E; Bianchi N; Gambari R
Genes (Basel); 2023 Oct; 14(10):. PubMed ID: 37895276
[TBL] [Abstract][Full Text] [Related]
3. Induction of adult levels of β-globin in human erythroid cells that intrinsically express embryonic or fetal globin by transduction with KLF1 and BCL11A-XL.
Trakarnsanga K; Wilson MC; Lau W; Singleton BK; Parsons SF; Sakuntanaga P; Kurita R; Nakamura Y; Anstee DJ; Frayne J
Haematologica; 2014 Nov; 99(11):1677-85. PubMed ID: 25107887
[TBL] [Abstract][Full Text] [Related]
4. Simvastatin and t-butylhydroquinone suppress KLF1 and BCL11A gene expression and additively increase fetal hemoglobin in primary human erythroid cells.
Macari ER; Schaeffer EK; West RJ; Lowrey CH
Blood; 2013 Jan; 121(5):830-9. PubMed ID: 23223429
[TBL] [Abstract][Full Text] [Related]
5. Binding patterns of BCL11A in the globin and GATA1 loci and characterization of the BCL11A fetal hemoglobin locus.
Jawaid K; Wahlberg K; Thein SL; Best S
Blood Cells Mol Dis; 2010 Aug; 45(2):140-6. PubMed ID: 20542454
[TBL] [Abstract][Full Text] [Related]
6. Acyclovir induces fetal hemoglobin via downregulation of γ-globin repressors, BCL11A and SOX6 trans-acting factors.
Ali H; Khan F; Ghulam Musharraf S
Biochem Pharmacol; 2021 Aug; 190():114612. PubMed ID: 34010599
[TBL] [Abstract][Full Text] [Related]
7. Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A.
Sankaran VG; Menne TF; Xu J; Akie TE; Lettre G; Van Handel B; Mikkola HK; Hirschhorn JN; Cantor AB; Orkin SH
Science; 2008 Dec; 322(5909):1839-42. PubMed ID: 19056937
[TBL] [Abstract][Full Text] [Related]
8. Base editing of key residues in the BCL11A-XL-specific zinc finger domains derepresses fetal globin expression.
Rajendiran V; Devaraju N; Haddad M; Ravi NS; Panigrahi L; Paul J; Gopalakrishnan C; Wyman S; Ariudainambi K; Mahalingam G; Periyasami Y; Prasad K; George A; Sukumaran D; Gopinathan S; Pai AA; Nakamura Y; Balasubramanian P; Ramalingam R; Thangavel S; Velayudhan SR; Corn JE; Mackay JP; Marepally S; Srivastava A; Crossley M; Mohankumar KM
Mol Ther; 2024 Mar; 32(3):663-677. PubMed ID: 38273654
[TBL] [Abstract][Full Text] [Related]
9. A combined approach for β-thalassemia based on gene therapy-mediated adult hemoglobin (HbA) production and fetal hemoglobin (HbF) induction.
Zuccato C; Breda L; Salvatori F; Breveglieri G; Gardenghi S; Bianchi N; Brognara E; Lampronti I; Borgatti M; Rivella S; Gambari R
Ann Hematol; 2012 Aug; 91(8):1201-13. PubMed ID: 22460946
[TBL] [Abstract][Full Text] [Related]
10. Mithramycin induces fetal hemoglobin production in normal and thalassemic human erythroid precursor cells.
Fibach E; Bianchi N; Borgatti M; Prus E; Gambari R
Blood; 2003 Aug; 102(4):1276-81. PubMed ID: 12738678
[TBL] [Abstract][Full Text] [Related]
11. Targeted deletion of BCL11A gene by CRISPR-Cas9 system for fetal hemoglobin reactivation: A promising approach for gene therapy of beta thalassemia disease.
Khosravi MA; Abbasalipour M; Concordet JP; Berg JV; Zeinali S; Arashkia A; Azadmanesh K; Buch T; Karimipoor M
Eur J Pharmacol; 2019 Jul; 854():398-405. PubMed ID: 31039344
[TBL] [Abstract][Full Text] [Related]
12. BCL11A-targeted γ-globin gene induction by triterpenoid glycosides of Fagonia indica: A preclinical scientific validation of indigenous herb for the treatment of β-hemoglobinopathies.
Iftikhar F; Khan MBN; Tehreem S; Kanwal N; Musharraf SG
Bioorg Chem; 2023 Nov; 140():106768. PubMed ID: 37586133
[TBL] [Abstract][Full Text] [Related]
13. Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch.
Liu N; Hargreaves VV; Zhu Q; Kurland JV; Hong J; Kim W; Sher F; Macias-Trevino C; Rogers JM; Kurita R; Nakamura Y; Yuan GC; Bauer DE; Xu J; Bulyk ML; Orkin SH
Cell; 2018 Apr; 173(2):430-442.e17. PubMed ID: 29606353
[TBL] [Abstract][Full Text] [Related]
14. BCL11A Down-Regulation Induces γ-Globin in Human β-Thalassemia Major Erythroid Cells.
Li J; Lai Y; Shi L
Hemoglobin; 2018 Jul; 42(4):225-230. PubMed ID: 30821197
[TBL] [Abstract][Full Text] [Related]
15. Development of a double shmiR lentivirus effectively targeting both BCL11A and ZNF410 for enhanced induction of fetal hemoglobin to treat β-hemoglobinopathies.
Liu B; Brendel C; Vinjamur DS; Zhou Y; Harris C; McGuinness M; Manis JP; Bauer DE; Xu H; Williams DA
Mol Ther; 2022 Aug; 30(8):2693-2708. PubMed ID: 35526095
[TBL] [Abstract][Full Text] [Related]
16. The Novel Role of the B-Cell Lymphoma/Leukemia 11A (BCL11A) Gene in β-Thalassaemia Treatment.
Mahmoud Ahmed NH; Lai MI
Cardiovasc Hematol Disord Drug Targets; 2023; 22(4):226-236. PubMed ID: 36734897
[TBL] [Abstract][Full Text] [Related]
17. Transcriptional silencing of fetal hemoglobin by BCL11A.
Sankaran VG; Xu J; Orkin SH
Ann N Y Acad Sci; 2010 Aug; 1202():64-8. PubMed ID: 20712774
[TBL] [Abstract][Full Text] [Related]
18. [Effect of BCL11A gene on transcription of γ-globin gene].
Sun SC; Zhou ZM; Tu CQ; Peng YS; Song HW
Zhongguo Shi Yan Xue Ye Xue Za Zhi; 2013 Jun; 21(3):628-32. PubMed ID: 23815911
[TBL] [Abstract][Full Text] [Related]
19. Featured Article: Modulation of fetal hemoglobin in hereditary persistence of fetal hemoglobin deletion type-2, compared to Sicilian δβ-thalassemia, by BCL11A and SOX6-targeting microRNAs.
Fornari TA; Lanaro C; Albuquerque DM; Ferreira R; Costa FF
Exp Biol Med (Maywood); 2017 Feb; 242(3):267-274. PubMed ID: 27591578
[TBL] [Abstract][Full Text] [Related]
20. MicroRNA-486-3p regulates γ-globin expression in human erythroid cells by directly modulating BCL11A.
Lulli V; Romania P; Morsilli O; Cianciulli P; Gabbianelli M; Testa U; Giuliani A; Marziali G
PLoS One; 2013; 8(4):e60436. PubMed ID: 23593217
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]