192 related articles for article (PubMed ID: 26342260)
41. Molecular analysis of the erythroid phenotype of a patient with BCL11A haploinsufficiency.
Wessels MW; Cnossen MH; van Dijk TB; Gillemans N; Schmidt KLJ; van Lom K; Vinjamur DS; Coyne S; Kurita R; Nakamura Y; de Man SA; Pfundt R; Azmani Z; Brouwer RWW; Bauer DE; van den Hout MCGN; van IJcken WFJ; Philipsen S
Blood Adv; 2021 May; 5(9):2339-2349. PubMed ID: 33938942
[TBL] [Abstract][Full Text] [Related]
42. Erythroid induction of K562 cells treated with mithramycin is associated with inhibition of raptor gene transcription and mammalian target of rapamycin complex 1 (mTORC1) functions.
Finotti A; Bianchi N; Fabbri E; Borgatti M; Breveglieri G; Gasparello J; Gambari R
Pharmacol Res; 2015 Jan; 91():57-68. PubMed ID: 25478892
[TBL] [Abstract][Full Text] [Related]
43. Hemoglobin genetics: recent contributions of GWAS and gene editing.
Smith EC; Orkin SH
Hum Mol Genet; 2016 Oct; 25(R2):R99-R105. PubMed ID: 27340226
[TBL] [Abstract][Full Text] [Related]
44. SIRT1 activates the expression of fetal hemoglobin genes.
Dai Y; Chen T; Ijaz H; Cho EH; Steinberg MH
Am J Hematol; 2017 Nov; 92(11):1177-1186. PubMed ID: 28776729
[TBL] [Abstract][Full Text] [Related]
45. Tenofovir disoproxil fumarate induces fetal hemoglobin production in K562 cells and β-YAC transgenic mice: A therapeutic approach for γ-globin induction.
Khan F; Ali H; Musharraf SG
Exp Cell Res; 2020 Sep; 394(2):112168. PubMed ID: 32653411
[TBL] [Abstract][Full Text] [Related]
46. Recent advances in globin research using genome-wide association studies and gene editing.
Orkin SH
Ann N Y Acad Sci; 2016 Mar; 1368(1):5-10. PubMed ID: 26866328
[TBL] [Abstract][Full Text] [Related]
47. An Aγ-globin G->A gene polymorphism associated with β
Breveglieri G; Bianchi N; Cosenza LC; Gamberini MR; Chiavilli F; Zuccato C; Montagner G; Borgatti M; Lampronti I; Finotti A; Gambari R
BMC Med Genet; 2017 Aug; 18(1):93. PubMed ID: 28851297
[TBL] [Abstract][Full Text] [Related]
48. Transcription factors LRF and BCL11A independently repress expression of fetal hemoglobin.
Masuda T; Wang X; Maeda M; Canver MC; Sher F; Funnell AP; Fisher C; Suciu M; Martyn GE; Norton LJ; Zhu C; Kurita R; Nakamura Y; Xu J; Higgs DR; Crossley M; Bauer DE; Orkin SH; Kharchenko PV; Maeda T
Science; 2016 Jan; 351(6270):285-9. PubMed ID: 26816381
[TBL] [Abstract][Full Text] [Related]
49. BCL11A mRNA Targeting by miR-210: A Possible Network Regulating γ-Globin Gene Expression.
Gasparello J; Fabbri E; Bianchi N; Breveglieri G; Zuccato C; Borgatti M; Gambari R; Finotti A
Int J Mol Sci; 2017 Nov; 18(12):. PubMed ID: 29186860
[TBL] [Abstract][Full Text] [Related]
50. Transcriptional regulators Myb and BCL11A interplay with DNA methyltransferase 1 in developmental silencing of embryonic and fetal β-like globin genes.
Roosjen M; McColl B; Kao B; Gearing LJ; Blewitt ME; Vadolas J
FASEB J; 2014 Apr; 28(4):1610-20. PubMed ID: 24371119
[TBL] [Abstract][Full Text] [Related]
51. Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencing.
Xu J; Peng C; Sankaran VG; Shao Z; Esrick EB; Chong BG; Ippolito GC; Fujiwara Y; Ebert BL; Tucker PW; Orkin SH
Science; 2011 Nov; 334(6058):993-6. PubMed ID: 21998251
[TBL] [Abstract][Full Text] [Related]
52. Hydroxyurea down-regulates BCL11A, KLF-1 and MYB through miRNA-mediated actions to induce γ-globin expression: implications for new therapeutic approaches of sickle cell disease.
Pule GD; Mowla S; Novitzky N; Wonkam A
Clin Transl Med; 2016 Mar; 5(1):15. PubMed ID: 27056246
[TBL] [Abstract][Full Text] [Related]
53. Pathogenic BCL11A variants provide insights into the mechanisms of human fetal hemoglobin silencing.
Shen Y; Li R; Teichert K; Montbleau KE; Verboon JM; Voit RA; Sankaran VG
PLoS Genet; 2021 Oct; 17(10):e1009835. PubMed ID: 34634037
[TBL] [Abstract][Full Text] [Related]
54. An erythroid enhancer of BCL11A subject to genetic variation determines fetal hemoglobin level.
Bauer DE; Kamran SC; Lessard S; Xu J; Fujiwara Y; Lin C; Shao Z; Canver MC; Smith EC; Pinello L; Sabo PJ; Vierstra J; Voit RA; Yuan GC; Porteus MH; Stamatoyannopoulos JA; Lettre G; Orkin SH
Science; 2013 Oct; 342(6155):253-7. PubMed ID: 24115442
[TBL] [Abstract][Full Text] [Related]
55. Phenotypic-screening generates active novel fetal globin-inducers that downregulate Bcl11a in a monkey model.
Makino T; Haruyama M; Katayama K; Terashima H; Tsunemi T; Miyazaki K; Terakawa M; Yamashiro K; Yoshioka R; Maeda H
Biochem Pharmacol; 2020 Jan; 171():113717. PubMed ID: 31751536
[TBL] [Abstract][Full Text] [Related]
56. Natural regulatory mutations elevate the fetal globin gene via disruption of BCL11A or ZBTB7A binding.
Martyn GE; Wienert B; Yang L; Shah M; Norton LJ; Burdach J; Kurita R; Nakamura Y; Pearson RCM; Funnell APW; Quinlan KGR; Crossley M
Nat Genet; 2018 Apr; 50(4):498-503. PubMed ID: 29610478
[TBL] [Abstract][Full Text] [Related]
57. Identification of fetal hemoglobin-inducing agents using the human leukemia KU812 cell line.
Zein S; Li W; Ramakrishnan V; Lou TF; Sivanand S; Mackie A; Pace B
Exp Biol Med (Maywood); 2010 Nov; 235(11):1385-94. PubMed ID: 20975082
[TBL] [Abstract][Full Text] [Related]
58. The rs61742690 (S783N) single nucleotide polymorphism is a suitable target for disrupting BCL11A-mediated foetal-to-adult globin switching.
Abdulazeez S; Sultana S; Almandil NB; Almohazey D; Bency BJ; Borgio JF
PLoS One; 2019; 14(2):e0212492. PubMed ID: 30768627
[TBL] [Abstract][Full Text] [Related]
59. Association between Variants at BCL11A Erythroid-Specific Enhancer and Fetal Hemoglobin Levels among Sickle Cell Disease Patients in Cameroon: Implications for Future Therapeutic Interventions.
Pule GD; Ngo Bitoungui VJ; Chetcha Chemegni B; Kengne AP; Antonarakis S; Wonkam A
OMICS; 2015 Oct; 19(10):627-31. PubMed ID: 26393293
[TBL] [Abstract][Full Text] [Related]
60. Comparative analysis of lentiviral gene transfer approaches designed to promote fetal hemoglobin production for the treatment of β-hemoglobinopathies.
Daniel-Moreno A; Lamsfus-Calle A; Wilber A; Chambers CB; Johnston I; Antony JS; Epting T; Handgretinger R; Mezger M
Blood Cells Mol Dis; 2020 Sep; 84():102456. PubMed ID: 32498026
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
