BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

209 related articles for article (PubMed ID: 26342652)

  • 1. Proteolytic processing of the neuronal ceroid lipofuscinosis related lysosomal protein CLN5.
    De Silva B; Adams J; Lee SY
    Exp Cell Res; 2015 Oct; 338(1):45-53. PubMed ID: 26342652
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The neuronal ceroid lipofuscinosis protein CLN5: new insights into cellular maturation, transport, and consequences of mutations.
    Schmiedt ML; Bessa C; Heine C; Ribeiro MG; Jalanko A; Kyttälä A
    Hum Mutat; 2010 Mar; 31(3):356-65. PubMed ID: 20052765
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of storage pathology in prenatal CLN5-deficient sheep neural cultures by lentiviral gene therapy.
    Hughes SM; Hope KM; Xu JB; Mitchell NL; Palmer DN
    Neurobiol Dis; 2014 Feb; 62():543-50. PubMed ID: 24269732
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Lysosomal localization of the neuronal ceroid lipofuscinosis CLN5 protein.
    Isosomppi J; Vesa J; Jalanko A; Peltonen L
    Hum Mol Genet; 2002 Apr; 11(8):885-91. PubMed ID: 11971870
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Retention of lysosomal protein CLN5 in the endoplasmic reticulum causes neuronal ceroid lipofuscinosis in Asian sibship.
    Lebrun AH; Storch S; Rüschendorf F; Schmiedt ML; Kyttälä A; Mole SE; Kitzmüller C; Saar K; Mewasingh LD; Boda V; Kohlschütter A; Ullrich K; Braulke T; Schulz A
    Hum Mutat; 2009 May; 30(5):E651-61. PubMed ID: 19309691
    [TBL] [Abstract][Full Text] [Related]  

  • 6. An Alzheimer's Disease-Linked Loss-of-Function CLN5 Variant Impairs Cathepsin D Maturation, Consistent with a Retromer Trafficking Defect.
    Qureshi YH; Patel VM; Berman DE; Kothiya MJ; Neufeld JL; Vardarajan B; Tang M; Reyes-Dumeyer D; Lantigua R; Medrano M; Jiménez-Velázquez IJ; Small SA; Reitz C
    Mol Cell Biol; 2018 Oct; 38(20):. PubMed ID: 30037983
    [TBL] [Abstract][Full Text] [Related]  

  • 7. KCTD7 mutations impair the trafficking of lysosomal enzymes through CLN5 accumulation to cause neuronal ceroid lipofuscinoses.
    Wang Y; Cao X; Liu P; Zeng W; Peng R; Shi Q; Feng K; Zhang P; Sun H; Wang C; Wang H
    Sci Adv; 2022 Aug; 8(31):eabm5578. PubMed ID: 35921411
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Neuronal ceroid lipofuscinoses are connected at molecular level: interaction of CLN5 protein with CLN2 and CLN3.
    Vesa J; Chin MH; Oelgeschläger K; Isosomppi J; DellAngelica EC; Jalanko A; Peltonen L
    Mol Biol Cell; 2002 Jul; 13(7):2410-20. PubMed ID: 12134079
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Autophagy-lysosome pathway alterations and alpha-synuclein up-regulation in the subtype of neuronal ceroid lipofuscinosis, CLN5 disease.
    Adams J; Feuerborn M; Molina JA; Wilden AR; Adhikari B; Budden T; Lee SY
    Sci Rep; 2019 Jan; 9(1):151. PubMed ID: 30655561
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CLN5 is cleaved by members of the SPP/SPPL family to produce a mature soluble protein.
    Jules F; Sauvageau E; Dumaresq-Doiron K; Mazzaferri J; Haug-Kröper M; Fluhrer R; Costantino S; Lefrancois S
    Exp Cell Res; 2017 Aug; 357(1):40-50. PubMed ID: 28442266
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A lysosomal enigma CLN5 and its significance in understanding neuronal ceroid lipofuscinosis.
    Basak I; Wicky HE; McDonald KO; Xu JB; Palmer JE; Best HL; Lefrancois S; Lee SY; Schoderboeck L; Hughes SM
    Cell Mol Life Sci; 2021 May; 78(10):4735-4763. PubMed ID: 33792748
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lysosomal dysfunction, autophagic defects, and CLN5 accumulation underlie the pathogenesis of KCTD7-mutated neuronal ceroid lipofuscinoses.
    Wang Y; Wang H; Wang C
    Autophagy; 2023 Jun; 19(6):1876-1878. PubMed ID: 36368077
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Topology and membrane anchoring of the lysosomal storage disease-related protein CLN5.
    Larkin H; Ribeiro MG; Lavoie C
    Hum Mutat; 2013 Dec; 34(12):1688-97. PubMed ID: 24038957
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The role of N-glycosylation in folding, trafficking, and functionality of lysosomal protein CLN5.
    Moharir A; Peck SH; Budden T; Lee SY
    PLoS One; 2013; 8(9):e74299. PubMed ID: 24058541
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Loss of CLN7 results in depletion of soluble lysosomal proteins and impaired mTOR reactivation.
    Danyukova T; Ariunbat K; Thelen M; Brocke-Ahmadinejad N; Mole SE; Storch S
    Hum Mol Genet; 2018 May; 27(10):1711-1722. PubMed ID: 29514215
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterisation of early changes in ovine CLN5 and CLN6 Batten disease neural cultures for the rapid screening of therapeutics.
    Best HL; Neverman NJ; Wicky HE; Mitchell NL; Leitch B; Hughes SM
    Neurobiol Dis; 2017 Apr; 100():62-74. PubMed ID: 28065762
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The role of ceroid lipofuscinosis neuronal protein 5 (CLN5) in endosomal sorting.
    Mamo A; Jules F; Dumaresq-Doiron K; Costantino S; Lefrancois S
    Mol Cell Biol; 2012 May; 32(10):1855-66. PubMed ID: 22431521
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The mouse ortholog of the neuronal ceroid lipofuscinosis CLN5 gene encodes a soluble lysosomal glycoprotein expressed in the developing brain.
    Holmberg V; Jalanko A; Isosomppi J; Fabritius AL; Peltonen L; Kopra O
    Neurobiol Dis; 2004 Jun; 16(1):29-40. PubMed ID: 15207259
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel interactions of CLN5 support molecular networking between Neuronal Ceroid Lipofuscinosis proteins.
    Lyly A; von Schantz C; Heine C; Schmiedt ML; Sipilä T; Jalanko A; Kyttälä A
    BMC Cell Biol; 2009 Nov; 10():83. PubMed ID: 19941651
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Novel Mutations in CLN5 of Chinese Patients With Neuronal Ceroid Lipofuscinosis.
    Ge L; Li HY; Hai Y; Min L; Xing L; Min J; Shu HX; Mei OY; Hua L
    J Child Neurol; 2018 Nov; 33(13):837-850. PubMed ID: 30264640
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.