407 related articles for article (PubMed ID: 26343845)
1. Characterization of cerebral microvasculature in transgenic mice with endothelium targeted over-expression of GTP-cyclohydrolase I.
Santhanam AV; d'Uscio LV; Katusic ZS
Brain Res; 2015 Nov; 1625():198-205. PubMed ID: 26343845
[TBL] [Abstract][Full Text] [Related]
2. Uncoupling of endothelial nitric oxide synthase in cerebral vasculature of Tg2576 mice.
Santhanam AV; d'Uscio LV; He T; Das P; Younkin SG; Katusic ZS
J Neurochem; 2015 Sep; 134(6):1129-38. PubMed ID: 26111938
[TBL] [Abstract][Full Text] [Related]
3. Erythropoietin increases bioavailability of tetrahydrobiopterin and protects cerebral microvasculature against oxidative stress induced by eNOS uncoupling.
Santhanam AV; d'Uscio LV; Katusic ZS
J Neurochem; 2014 Nov; 131(4):521-9. PubMed ID: 25041251
[TBL] [Abstract][Full Text] [Related]
4. Critical role for tetrahydrobiopterin recycling by dihydrofolate reductase in regulation of endothelial nitric-oxide synthase coupling: relative importance of the de novo biopterin synthesis versus salvage pathways.
Crabtree MJ; Tatham AL; Hale AB; Alp NJ; Channon KM
J Biol Chem; 2009 Oct; 284(41):28128-28136. PubMed ID: 19666465
[TBL] [Abstract][Full Text] [Related]
5. Relationships between nitric oxide-mediated endothelial function, eNOS coupling and blood pressure revealed by eNOS-GTP cyclohydrolase 1 double transgenic mice.
Adlam D; Bendall JK; De Bono JP; Alp NJ; Khoo J; Nicoli T; Yokoyama M; Kawashima S; Channon KM
Exp Physiol; 2007 Jan; 92(1):119-26. PubMed ID: 17012144
[TBL] [Abstract][Full Text] [Related]
6. Increased endothelial tetrahydrobiopterin synthesis by targeted transgenic GTP-cyclohydrolase I overexpression reduces endothelial dysfunction and atherosclerosis in ApoE-knockout mice.
Alp NJ; McAteer MA; Khoo J; Choudhury RP; Channon KM
Arterioscler Thromb Vasc Biol; 2004 Mar; 24(3):445-50. PubMed ID: 14707037
[TBL] [Abstract][Full Text] [Related]
7. Endothelium-specific GTP cyclohydrolase I overexpression attenuates blood pressure progression in salt-sensitive low-renin hypertension.
Du YH; Guan YY; Alp NJ; Channon KM; Chen AF
Circulation; 2008 Feb; 117(8):1045-54. PubMed ID: 18268143
[TBL] [Abstract][Full Text] [Related]
8. GTP cyclohydrolase I gene transfer augments intracellular tetrahydrobiopterin in human endothelial cells: effects on nitric oxide synthase activity, protein levels and dimerisation.
Cai S; Alp NJ; McDonald D; Smith I; Kay J; Canevari L; Heales S; Channon KM
Cardiovasc Res; 2002 Sep; 55(4):838-49. PubMed ID: 12176133
[TBL] [Abstract][Full Text] [Related]
9. Quantitative regulation of intracellular endothelial nitric-oxide synthase (eNOS) coupling by both tetrahydrobiopterin-eNOS stoichiometry and biopterin redox status: insights from cells with tet-regulated GTP cyclohydrolase I expression.
Crabtree MJ; Tatham AL; Al-Wakeel Y; Warrick N; Hale AB; Cai S; Channon KM; Alp NJ
J Biol Chem; 2009 Jan; 284(2):1136-44. PubMed ID: 19011239
[TBL] [Abstract][Full Text] [Related]
10. Hydrogen peroxide stimulates tetrahydrobiopterin synthesis through the induction of GTP-cyclohydrolase I and increases nitric oxide synthase activity in vascular endothelial cells.
Shimizu S; Shiota K; Yamamoto S; Miyasaka Y; Ishii M; Watabe T; Nishida M; Mori Y; Yamamoto T; Kiuchi Y
Free Radic Biol Med; 2003 May; 34(10):1343-52. PubMed ID: 12726922
[TBL] [Abstract][Full Text] [Related]
11. Cell type-specific recycling of tetrahydrobiopterin by dihydrofolate reductase explains differential effects of 7,8-dihydrobiopterin on endothelial nitric oxide synthase uncoupling.
Schmidt K; Kolesnik B; Gorren AC; Werner ER; Mayer B
Biochem Pharmacol; 2014 Aug; 90(3):246-53. PubMed ID: 24863258
[TBL] [Abstract][Full Text] [Related]
12. Tetrahydrobiopterin-dependent preservation of nitric oxide-mediated endothelial function in diabetes by targeted transgenic GTP-cyclohydrolase I overexpression.
Alp NJ; Mussa S; Khoo J; Cai S; Guzik T; Jefferson A; Goh N; Rockett KA; Channon KM
J Clin Invest; 2003 Sep; 112(5):725-35. PubMed ID: 12952921
[TBL] [Abstract][Full Text] [Related]
13. Augmented BH4 by gene transfer restores nitric oxide synthase function in hyperglycemic human endothelial cells.
Cai S; Khoo J; Channon KM
Cardiovasc Res; 2005 Mar; 65(4):823-31. PubMed ID: 15721862
[TBL] [Abstract][Full Text] [Related]
14. Gene transfer of human guanosine 5'-triphosphate cyclohydrolase I restores vascular tetrahydrobiopterin level and endothelial function in low renin hypertension.
Zheng JS; Yang XQ; Lookingland KJ; Fink GD; Hesslinger C; Kapatos G; Kovesdi I; Chen AF
Circulation; 2003 Sep; 108(10):1238-45. PubMed ID: 12925450
[TBL] [Abstract][Full Text] [Related]
15. Tetrahydrobiopterin recycling, a key determinant of endothelial nitric-oxide synthase-dependent signaling pathways in cultured vascular endothelial cells.
Sugiyama T; Levy BD; Michel T
J Biol Chem; 2009 May; 284(19):12691-700. PubMed ID: 19286667
[TBL] [Abstract][Full Text] [Related]
16. Stoichiometric relationships between endothelial tetrahydrobiopterin, endothelial NO synthase (eNOS) activity, and eNOS coupling in vivo: insights from transgenic mice with endothelial-targeted GTP cyclohydrolase 1 and eNOS overexpression.
Bendall JK; Alp NJ; Warrick N; Cai S; Adlam D; Rockett K; Yokoyama M; Kawashima S; Channon KM
Circ Res; 2005 Oct; 97(9):864-71. PubMed ID: 16179591
[TBL] [Abstract][Full Text] [Related]
17. HMG-CoA reductase inhibitor increases GTP cyclohydrolase I mRNA and tetrahydrobiopterin in vascular endothelial cells.
Hattori Y; Nakanishi N; Akimoto K; Yoshida M; Kasai K
Arterioscler Thromb Vasc Biol; 2003 Feb; 23(2):176-82. PubMed ID: 12588756
[TBL] [Abstract][Full Text] [Related]
18. A key role for tetrahydrobiopterin-dependent endothelial NOS regulation in resistance arteries: studies in endothelial cell tetrahydrobiopterin-deficient mice.
Chuaiphichai S; Crabtree MJ; Mcneill E; Hale AB; Trelfa L; Channon KM; Douglas G
Br J Pharmacol; 2017 Apr; 174(8):657-671. PubMed ID: 28128438
[TBL] [Abstract][Full Text] [Related]
19. Erythropoietin prevents endothelial dysfunction in GTP-cyclohydrolase I-deficient hph1 mice.
dʼUscio LV; Santhanam AV; Katusic ZS
J Cardiovasc Pharmacol; 2014 Dec; 64(6):514-21. PubMed ID: 25490417
[TBL] [Abstract][Full Text] [Related]
20. Dihydrofolate reductase protects endothelial nitric oxide synthase from uncoupling in tetrahydrobiopterin deficiency.
Crabtree MJ; Hale AB; Channon KM
Free Radic Biol Med; 2011 Jun; 50(11):1639-46. PubMed ID: 21402147
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
