These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

124 related articles for article (PubMed ID: 26344210)

  • 1. A High-Throughput (HTS) Assay for Enzyme Reaction Phenotyping in Human Recombinant P450 Enzymes Using LC-MS/MS.
    Li X; Suhar T; Glass L; Rajaraman G
    Curr Protoc Pharmacol; 2014 Mar; 64():9.18.1-10. PubMed ID: 26344210
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A high-throughput inhibition screening of major human cytochrome P450 enzymes using an in vitro cocktail and liquid chromatography-tandem mass spectrometry.
    Qin CZ; Ren X; Tan ZR; Chen Y; Yin JY; Yu J; Qu J; Zhou HH; Liu ZQ
    Biomed Chromatogr; 2014 Feb; 28(2):197-203. PubMed ID: 23946123
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Utility of intersystem extrapolation factors in early reaction phenotyping and the quantitative extrapolation of human liver microsomal intrinsic clearance using recombinant cytochromes P450.
    Chen Y; Liu L; Nguyen K; Fretland AJ
    Drug Metab Dispos; 2011 Mar; 39(3):373-82. PubMed ID: 21148079
    [TBL] [Abstract][Full Text] [Related]  

  • 4. An in vitro, high throughput, seven CYP cocktail inhibition assay for the evaluation of new chemical entities using LC-MS/MS.
    Otten JN; Hingorani GP; Hartley DP; Kragerud SD; Franklin RB
    Drug Metab Lett; 2011 Jan; 5(1):17-24. PubMed ID: 21198441
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A sensitive and high-throughput LC-MS/MS method for inhibition assay of seven major cytochrome P450s in human liver microsomes using an in vitro cocktail of probe substrates.
    Liu LY; Han YL; Zhu JH; Yu Q; Yang QJ; Lu J; Guo C
    Biomed Chromatogr; 2015 Mar; 29(3):437-44. PubMed ID: 25098274
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reliable high-throughput method for inhibition assay of 8 cytochrome P450 isoforms using cocktail of probe substrates and stable isotope-labeled internal standards.
    Kozakai K; Yamada Y; Oshikata M; Kawase T; Suzuki E; Haramaki Y; Taniguchi H
    Drug Metab Pharmacokinet; 2012; 27(5):520-9. PubMed ID: 22498647
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of human cytochrome P450 enzymes involved in the metabolism of cyamemazine.
    Arbus C; Benyamina A; Llorca PM; Baylé F; Bromet N; Massiere F; Garay RP; Hameg A
    Eur J Pharm Sci; 2007 Dec; 32(4-5):357-66. PubMed ID: 17951033
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Software-aided cytochrome P450 reaction phenotyping and kinetic analysis in early drug discovery.
    Cece-Esencan EN; Fontaine F; Plasencia G; Teppner M; Brink A; Pähler A; Zamora I
    Rapid Commun Mass Spectrom; 2016 Jan; 30(2):301-10. PubMed ID: 26689160
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A review of LC-MS techniques and high-throughput approaches used to investigate drug metabolism by cytochrome P450s.
    Youdim KA; Saunders KC
    J Chromatogr B Analyt Technol Biomed Life Sci; 2010 May; 878(17-18):1326-36. PubMed ID: 20207203
    [TBL] [Abstract][Full Text] [Related]  

  • 10. High-throughput screening of inhibitory potential of nine cytochrome P450 enzymes in vitro using liquid chromatography/tandem mass spectrometry.
    Kim MJ; Kim H; Cha IJ; Park JS; Shon JH; Liu KH; Shin JG
    Rapid Commun Mass Spectrom; 2005; 19(18):2651-8. PubMed ID: 16124035
    [TBL] [Abstract][Full Text] [Related]  

  • 11. High-Throughput Cytochrome P450 Cocktail Inhibition Assay for Assessing Drug-Drug and Drug-Botanical Interactions.
    Li G; Huang K; Nikolic D; van Breemen RB
    Drug Metab Dispos; 2015 Nov; 43(11):1670-8. PubMed ID: 26285764
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A cocktail approach for assessing the in vitro activity of human cytochrome P450s: an overview of current methodologies.
    Spaggiari D; Geiser L; Daali Y; Rudaz S
    J Pharm Biomed Anal; 2014 Dec; 101():221-37. PubMed ID: 24746851
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Simultaneous determination of tolbutamide, omeprazole, midazolam and dextromethorphan in human plasma by LC-MS/MS--a high throughput approach to evaluate drug-drug interactions.
    Zhang W; Han F; Guo P; Zhao H; Lin ZJ; Huang MQ; Bertelsen K; Weng N
    J Chromatogr B Analyt Technol Biomed Life Sci; 2010 May; 878(15-16):1169-77. PubMed ID: 20378422
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Development of GC-MS based cytochrome P450 assay for the investigation of multi-herb interaction.
    Oh HA; Lee H; Kim D; Jung BH
    Anal Biochem; 2017 Feb; 519():71-83. PubMed ID: 28007398
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A comprehensive assay for nine major cytochrome P450 enzymes activities with 16 probe reactions on human liver microsomes by a single LC/MS/MS run to support reliable in vitro inhibitory drug-drug interaction evaluation.
    Peng Y; Wu H; Zhang X; Zhang F; Qi H; Zhong Y; Wang Y; Sang H; Wang G; Sun J
    Xenobiotica; 2015; 45(11):961-77. PubMed ID: 26007223
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A rapid and simple LC-MS/MS method for the simultaneous evaluation of CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP3A4 hydroxylation capacity.
    de Andrés F; Sosa-Macías M; Llerena A
    Bioanalysis; 2014 Mar; 6(5):683-96. PubMed ID: 24620810
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Study of in vitro metabolism of m-nisoldipine in human liver microsomes and recombinant cytochrome P450 enzymes by liquid chromatography-mass spectrometry.
    Yuan L; Jia P; Sun Y; Zhao C; Zhi X; Sheng N; Zhang L
    J Pharm Biomed Anal; 2014 Aug; 97():65-71. PubMed ID: 24816159
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Development and validation of an in vitro, seven-in-one human cytochrome P450 assay for evaluation of both direct and time-dependent inhibition.
    Dahlinger D; Duechting S; Nuecken D; Sydow K; Fuhr U; Frechen S
    J Pharmacol Toxicol Methods; 2016; 77():66-75. PubMed ID: 26528794
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Validated assays for human cytochrome P450 activities.
    Walsky RL; Obach RS
    Drug Metab Dispos; 2004 Jun; 32(6):647-60. PubMed ID: 15155557
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Liquid chromatography/tandem mass spectrometric determination of inhibition of human cytochrome P450 isozymes by resveratrol and resveratrol-3-sulfate.
    Yu C; Shin YG; Kosmeder JW; Pezzuto JM; van Breemen RB
    Rapid Commun Mass Spectrom; 2003; 17(4):307-13. PubMed ID: 12569440
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.