BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

391 related articles for article (PubMed ID: 26344911)

  • 1. Ynamide Click chemistry in development of triazole VEGFR2 TK modulators.
    Vojtičková M; Dobiaš J; Hanquet G; Addová G; Cetin-Atalay R; Yildirim DC; Boháč A
    Eur J Med Chem; 2015 Oct; 103():105-22. PubMed ID: 26344911
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A development of chimeric VEGFR2 TK inhibitor based on two ligand conformers from PDB: 1Y6A complex--medicinal chemistry consequences of a TKs analysis.
    Lintnerová L; García-Caballero M; Gregáň F; Melicherčík M; Quesada AR; Dobiaš J; Lác J; Sališová M; Boháč A
    Eur J Med Chem; 2014 Jan; 72():146-59. PubMed ID: 24368209
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and in vitro evaluation of potential anticancer activity of mono- and bis-1,2,3-triazole derivatives of bis-alkynes.
    Elamari H; Slimi R; Chabot GG; Quentin L; Scherman D; Girard C
    Eur J Med Chem; 2013 Feb; 60():360-4. PubMed ID: 23314049
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis of 1,4-disubstituted 1,2,3-triazole Derivatives Using Click Chemistry and their Src Kinase Activities.
    Lebeau A; Abrioux C; Bénimèlis D; Benfodda Z; Meffre P
    Med Chem; 2016; 13(1):40-48. PubMed ID: 27041552
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Click chemistry based synthesis, cytotoxic activity and molecular docking of novel triazole-thienopyrimidine hybrid glycosides targeting EGFR.
    Khattab RR; Alshamari AK; Hassan AA; Elganzory HH; El-Sayed WA; Awad HM; Nossier ES; Hassan NA
    J Enzyme Inhib Med Chem; 2021 Dec; 36(1):504-516. PubMed ID: 33504239
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis, and evaluation of novel VEGFR2 kinase inhibitors: discovery of [1,2,4]triazolo[1,5-a]pyridine derivatives with slow dissociation kinetics.
    Oguro Y; Cary DR; Miyamoto N; Tawada M; Iwata H; Miki H; Hori A; Imamura S
    Bioorg Med Chem; 2013 Aug; 21(15):4714-29. PubMed ID: 23755884
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis, in vitro anticancer activity and in silico studies of certain isoxazole-based carboxamides, ureates, and hydrazones as potential inhibitors of VEGFR2.
    Abou-Seri SM; Eissa AAM; Behery MGM; Omar FA
    Bioorg Chem; 2021 Nov; 116():105334. PubMed ID: 34534755
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis, Molecular Modeling and Biological Evaluation of 4-Alkoxyquinazoline Derivatives as Novel Inhibitors of VEGFR2.
    Lu L; Zhao TT; Liu TB; Sun WX; Xu C; Li DD; Zhu HL
    Chem Pharm Bull (Tokyo); 2016 Nov; 64(11):1570-1575. PubMed ID: 27568484
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Novel scaffold hopping of potent benzothiazole and isatin analogues linked to 1,2,3-triazole fragment that mimic quinazoline epidermal growth factor receptor inhibitors: Synthesis, antitumor and mechanistic analyses.
    Rezki N; Almehmadi MA; Ihmaid S; Shehata AM; Omar AM; Ahmed HEA; Aouad MR
    Bioorg Chem; 2020 Oct; 103():104133. PubMed ID: 32745759
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-based design, synthesis, and evaluation of imidazo[1,2-b]pyridazine and imidazo[1,2-a]pyridine derivatives as novel dual c-Met and VEGFR2 kinase inhibitors.
    Matsumoto S; Miyamoto N; Hirayama T; Oki H; Okada K; Tawada M; Iwata H; Nakamura K; Yamasaki S; Miki H; Hori A; Imamura S
    Bioorg Med Chem; 2013 Dec; 21(24):7686-98. PubMed ID: 24216091
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis and molecular docking studies of novel N-benzenesulfonyl-1,2,3,4-tetrahydroisoquinoline-based triazoles with potential anticancer activity.
    Pingaew R; Mandi P; Nantasenamat C; Prachayasittikul S; Ruchirawat S; Prachayasittikul V
    Eur J Med Chem; 2014 Jun; 81():192-203. PubMed ID: 24836071
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery of novel substituted benzo-anellated 4-benzylamino pyrrolopyrimidines as dual EGFR and VEGFR2 inhibitors.
    Fischer T; Krüger T; Najjar A; Totzke F; Schächtele C; Sippl W; Ritter C; Hilgeroth A
    Bioorg Med Chem Lett; 2017 Jun; 27(12):2708-2712. PubMed ID: 28478927
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design and synthesis of novel 1,2,3-triazole derivatives of coronopilin as anti-cancer compounds.
    Khazir J; Hyder I; Gayatri JL; Prasad Yandrati L; Nalla N; Chasoo G; Mahajan A; Saxena AK; Alam MS; Qazi GN; Sampath Kumar HM
    Eur J Med Chem; 2014 Jul; 82():255-62. PubMed ID: 24910974
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Novel thioureido-benzenesulfonamide derivatives with enaminone linker as potent anticancer, radiosensitizers and VEGFR2 inhibitors.
    Ghorab MM; Ragab FA; Heiba HI; El-Gazzar MG; El-Gazzar MGM
    Bioorg Med Chem Lett; 2018 May; 28(9):1464-1470. PubMed ID: 29628325
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Rational design, synthesis and anti-proliferative evaluation of novel 1,4-benzoxazine-[1,2,3]triazole hybrids.
    Bollu R; Palem JD; Bantu R; Guguloth V; Nagarapu L; Polepalli S; Jain N
    Eur J Med Chem; 2015 Jan; 89():138-46. PubMed ID: 25462234
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of novel indolyl-1,2,4-triazole hybrids as potent vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitors with potential anti-renal cancer activity.
    Al-Hussain SA; Farghaly TA; Zaki MEA; Abdulwahab HG; Al-Qurashi NT; Muhammad ZA
    Bioorg Chem; 2020 Dec; 105():104330. PubMed ID: 33038552
    [TBL] [Abstract][Full Text] [Related]  

  • 17. New amide linked dimeric 1,2,3-triazoles bearing aryloxy scaffolds as a potent antiproliferative agents and EGFR tyrosine kinase phosphorylation inhibitors.
    Deshmukh TR; Sarkate AP; Lokwani DK; Tiwari SV; Azad R; Shingate BB
    Bioorg Med Chem Lett; 2019 Oct; 29(19):126618. PubMed ID: 31431361
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis, biological evaluation and molecular docking studies of novel 1,2,3-triazole-quinazolines as antiproliferative agents displaying ERK inhibitory activity.
    Nunes PSG; da Silva G; Nascimento S; Mantoani SP; de Andrade P; Bernardes ES; Kawano DF; Leopoldino AM; Carvalho I
    Bioorg Chem; 2021 Aug; 113():104982. PubMed ID: 34020277
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Natural inspired piperine-based ureas and amides as novel antitumor agents towards breast cancer.
    Elimam DM; Elgazar AA; El-Senduny FF; El-Domany RA; Badria FA; Eldehna WM
    J Enzyme Inhib Med Chem; 2022 Dec; 37(1):39-50. PubMed ID: 34894962
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design and synthesis of novel 2-(4-(2-(dimethylamino)ethyl)-4H-1,2,4-triazol-3-yl)pyridines as potential antitumor agents.
    Qin M; Zhai X; Xie H; Ma J; Lu K; Wang Y; Wang L; Gu Y; Gong P
    Eur J Med Chem; 2014 Jun; 81():47-58. PubMed ID: 24826815
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.