BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

96 related articles for article (PubMed ID: 26347528)

  • 1. B-Raf inhibition in conjunctival melanoma cell lines with PLX 4720.
    Riechardt AI; Maier AK; Nonnenmacher A; Reichhart N; Keilholz U; Kociok N; Strauss O; Joussen AM; Gundlach E
    Br J Ophthalmol; 2015 Dec; 99(12):1739-45. PubMed ID: 26347528
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PLX-4032, a small-molecule B-Raf inhibitor for the potential treatment of malignant melanoma.
    Smalley KS
    Curr Opin Investig Drugs; 2010 Jun; 11(6):699-706. PubMed ID: 20496265
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 17-AAG and 17-DMAG-induced inhibition of cell proliferation through B-Raf downregulation in WT B-Raf-expressing uveal melanoma cell lines.
    Babchia N; Calipel A; Mouriaux F; Faussat AM; Mascarelli F
    Invest Ophthalmol Vis Sci; 2008 Jun; 49(6):2348-56. PubMed ID: 18281615
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Differential sensitivity of melanoma cell lines with differing B-Raf mutational status to the new oncogenic B-Raf kinase inhibitor UI-152.
    Kim YK; Ahn SK; Lee M
    Cancer Lett; 2012 Jul; 320(2):215-24. PubMed ID: 22425959
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The PI3K/Akt and mTOR/P70S6K signaling pathways in human uveal melanoma cells: interaction with B-Raf/ERK.
    Babchia N; Calipel A; Mouriaux F; Faussat AM; Mascarelli F
    Invest Ophthalmol Vis Sci; 2010 Jan; 51(1):421-9. PubMed ID: 19661225
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The BH3-mimetic ABT-737 sensitizes human melanoma cells to apoptosis induced by selective BRAF inhibitors but does not reverse acquired resistance.
    Wroblewski D; Mijatov B; Mohana-Kumaran N; Lai F; Gallagher SJ; Haass NK; Zhang XD; Hersey P
    Carcinogenesis; 2013 Feb; 34(2):237-47. PubMed ID: 23087082
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Chemosensitivity of conjunctival melanoma cell lines to single chemotherapeutic agents and combinations.
    Westekemper H; Freistuehler M; Anastassiou G; Nareyeck G; Bornfeld N; Steuhl KP; Scheulen ME; Hilger RA
    Br J Ophthalmol; 2012 Apr; 96(4):591-6. PubMed ID: 22275346
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Melanoma cells show a heterogeneous range of sensitivity to ionizing radiation and are radiosensitized by inhibition of B-RAF with PLX-4032.
    Sambade MJ; Peters EC; Thomas NE; Kaufmann WK; Kimple RJ; Shields JM
    Radiother Oncol; 2011 Mar; 98(3):394-9. PubMed ID: 21295875
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Genotype-dependent sensitivity of uveal melanoma cell lines to inhibition of B-Raf, MEK, and Akt kinases: rationale for personalized therapy.
    Mitsiades N; Chew SA; He B; Riechardt AI; Karadedou T; Kotoula V; Poulaki V
    Invest Ophthalmol Vis Sci; 2011 Sep; 52(10):7248-55. PubMed ID: 21828154
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Anti-apoptotic BCL-2 proteins govern cellular outcome following B-RAF(V600E) inhibition and can be targeted to reduce resistance.
    Serasinghe MN; Missert DJ; Asciolla JJ; Podgrabinska S; Wieder SY; Izadmehr S; Belbin G; Skobe M; Chipuk JE
    Oncogene; 2015 Feb; 34(7):857-67. PubMed ID: 24608435
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Apoptosis of human melanoma cells induced by inhibition of B-RAFV600E involves preferential splicing of bimS.
    Jiang CC; Lai F; Tay KH; Croft A; Rizos H; Becker TM; Yang F; Liu H; Thorne RF; Hersey P; Zhang XD
    Cell Death Dis; 2010 Sep; 1(9):e69. PubMed ID: 21364673
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evaluation of (fli:GFP) Casper Zebrafish Embryos as a Model for Human Conjunctival Melanoma.
    Pontes KCS; Groenewoud A; Cao J; Ataide LMS; Snaar-Jagalska E; Jager MJ
    Invest Ophthalmol Vis Sci; 2017 Dec; 58(14):6065-6071. PubMed ID: 29204645
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The oncogenic BRAF kinase inhibitor PLX4032/RG7204 does not affect the viability or function of human lymphocytes across a wide range of concentrations.
    Comin-Anduix B; Chodon T; Sazegar H; Matsunaga D; Mock S; Jalil J; Escuin-Ordinas H; Chmielowski B; Koya RC; Ribas A
    Clin Cancer Res; 2010 Dec; 16(24):6040-8. PubMed ID: 21169256
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Single-Walled Carbon Nanohorns Inhibit Proliferation of Conjunctival Melanoma Cell Lines CRMM-1 and Involved in Energy Metabolism.
    Cao Y; Zhang Y; Zhao M
    J Nanosci Nanotechnol; 2015 Feb; 15(2):1821-30. PubMed ID: 26353738
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibitors of Raf kinase activity block growth of thyroid cancer cells with RET/PTC or BRAF mutations in vitro and in vivo.
    Ouyang B; Knauf JA; Smith EP; Zhang L; Ramsey T; Yusuff N; Batt D; Fagin JA
    Clin Cancer Res; 2006 Mar; 12(6):1785-93. PubMed ID: 16551863
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity.
    Tsai J; Lee JT; Wang W; Zhang J; Cho H; Mamo S; Bremer R; Gillette S; Kong J; Haass NK; Sproesser K; Li L; Smalley KS; Fong D; Zhu YL; Marimuthu A; Nguyen H; Lam B; Liu J; Cheung I; Rice J; Suzuki Y; Luu C; Settachatgul C; Shellooe R; Cantwell J; Kim SH; Schlessinger J; Zhang KY; West BL; Powell B; Habets G; Zhang C; Ibrahim PN; Hirth P; Artis DR; Herlyn M; Bollag G
    Proc Natl Acad Sci U S A; 2008 Feb; 105(8):3041-6. PubMed ID: 18287029
    [TBL] [Abstract][Full Text] [Related]  

  • 17. c-Met is a potentially new therapeutic target for treatment of human melanoma.
    Puri N; Ahmed S; Janamanchi V; Tretiakova M; Zumba O; Krausz T; Jagadeeswaran R; Salgia R
    Clin Cancer Res; 2007 Apr; 13(7):2246-53. PubMed ID: 17404109
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification and optimization of new dual inhibitors of B-Raf and epidermal growth factor receptor kinases for overcoming resistance against vemurafenib.
    Cheng H; Chang Y; Zhang L; Luo J; Tu Z; Lu X; Zhang Q; Lu J; Ren X; Ding K
    J Med Chem; 2014 Mar; 57(6):2692-703. PubMed ID: 24588073
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pyrophosphorolysis detects B-RAF mutations in primary uveal melanoma.
    Maat W; Kilic E; Luyten GP; de Klein A; Jager MJ; Gruis NA; Van der Velden PA
    Invest Ophthalmol Vis Sci; 2008 Jan; 49(1):23-7. PubMed ID: 18172070
    [TBL] [Abstract][Full Text] [Related]  

  • 20. C-Raf inhibits MAPK activation and transformation by B-Raf(V600E).
    Karreth FA; DeNicola GM; Winter SP; Tuveson DA
    Mol Cell; 2009 Nov; 36(3):477-86. PubMed ID: 19917255
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.