These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

438 related articles for article (PubMed ID: 26348909)

  • 1. GSK3-mediated raptor phosphorylation supports amino-acid-dependent mTORC1-directed signalling.
    Stretton C; Hoffmann TM; Munson MJ; Prescott A; Taylor PM; Ganley IG; Hundal HS
    Biochem J; 2015 Sep; 470(2):207-21. PubMed ID: 26348909
    [TBL] [Abstract][Full Text] [Related]  

  • 2. RhoA modulates signaling through the mechanistic target of rapamycin complex 1 (mTORC1) in mammalian cells.
    Gordon BS; Kazi AA; Coleman CS; Dennis MD; Chau V; Jefferson LS; Kimball SR
    Cell Signal; 2014 Mar; 26(3):461-7. PubMed ID: 24316235
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mitotic raptor promotes mTORC1 activity, G(2)/M cell cycle progression, and internal ribosome entry site-mediated mRNA translation.
    Ramírez-Valle F; Badura ML; Braunstein S; Narasimhan M; Schneider RJ
    Mol Cell Biol; 2010 Jul; 30(13):3151-64. PubMed ID: 20439490
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Intestinal cell kinase (ICK) promotes activation of mTOR complex 1 (mTORC1) through phosphorylation of Raptor Thr-908.
    Wu D; Chapman JR; Wang L; Harris TE; Shabanowitz J; Hunt DF; Fu Z
    J Biol Chem; 2012 Apr; 287(15):12510-9. PubMed ID: 22356909
    [TBL] [Abstract][Full Text] [Related]  

  • 5. ULK1 inhibits mTORC1 signaling, promotes multisite Raptor phosphorylation and hinders substrate binding.
    Dunlop EA; Hunt DK; Acosta-Jaquez HA; Fingar DC; Tee AR
    Autophagy; 2011 Jul; 7(7):737-47. PubMed ID: 21460630
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mammalian target of rapamycin signalling modulates amino acid uptake by regulating transporter cell surface abundance in primary human trophoblast cells.
    Rosario FJ; Kanai Y; Powell TL; Jansson T
    J Physiol; 2013 Feb; 591(3):609-25. PubMed ID: 23165769
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Regulation of mTOR complex 1 (mTORC1) by raptor Ser863 and multisite phosphorylation.
    Foster KG; Acosta-Jaquez HA; Romeo Y; Ekim B; Soliman GA; Carriere A; Roux PP; Ballif BA; Fingar DC
    J Biol Chem; 2010 Jan; 285(1):80-94. PubMed ID: 19864431
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Akt-dependent activation of mTORC1 complex involves phosphorylation of mTOR (mammalian target of rapamycin) by IκB kinase α (IKKα).
    Dan HC; Ebbs A; Pasparakis M; Van Dyke T; Basseres DS; Baldwin AS
    J Biol Chem; 2014 Sep; 289(36):25227-40. PubMed ID: 24990947
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hypoxia Increases IGFBP-1 Phosphorylation Mediated by mTOR Inhibition.
    Damerill I; Biggar KK; Abu Shehab M; Li SS; Jansson T; Gupta MB
    Mol Endocrinol; 2016 Feb; 30(2):201-16. PubMed ID: 26714229
    [TBL] [Abstract][Full Text] [Related]  

  • 10. mTORC1 and mTORC2 regulate insulin secretion through Akt in INS-1 cells.
    Le Bacquer O; Queniat G; Gmyr V; Kerr-Conte J; Lefebvre B; Pattou F
    J Endocrinol; 2013 Jan; 216(1):21-9. PubMed ID: 23092880
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Functional Proteomics Identifies Acinus L as a Direct Insulin- and Amino Acid-Dependent Mammalian Target of Rapamycin Complex 1 (mTORC1) Substrate.
    Schwarz JJ; Wiese H; Tölle RC; Zarei M; Dengjel J; Warscheid B; Thedieck K
    Mol Cell Proteomics; 2015 Aug; 14(8):2042-55. PubMed ID: 25907765
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PRR5, a novel component of mTOR complex 2, regulates platelet-derived growth factor receptor beta expression and signaling.
    Woo SY; Kim DH; Jun CB; Kim YM; Haar EV; Lee SI; Hegg JW; Bandhakavi S; Griffin TJ; Kim DH
    J Biol Chem; 2007 Aug; 282(35):25604-12. PubMed ID: 17599906
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Regulation of amino acid transporter trafficking by mTORC1 in primary human trophoblast cells is mediated by the ubiquitin ligase Nedd4-2.
    Rosario FJ; Dimasuay KG; Kanai Y; Powell TL; Jansson T
    Clin Sci (Lond); 2016 Apr; 130(7):499-512. PubMed ID: 26608079
    [TBL] [Abstract][Full Text] [Related]  

  • 14. GSK3 is required for rapalogs to induce degradation of some oncogenic proteins and to suppress cancer cell growth.
    Koo J; Wang X; Owonikoko TK; Ramalingam SS; Khuri FR; Sun SY
    Oncotarget; 2015 Apr; 6(11):8974-87. PubMed ID: 25797247
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Amino acids activate mammalian target of rapamycin (mTOR) complex 1 without changing Rag GTPase guanyl nucleotide charging.
    Oshiro N; Rapley J; Avruch J
    J Biol Chem; 2014 Jan; 289(5):2658-74. PubMed ID: 24337580
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Glycogen synthase kinase-3 (GSK3) inhibition induces prosurvival autophagic signals in human pancreatic cancer cells.
    Marchand B; Arsenault D; Raymond-Fleury A; Boisvert FM; Boucher MJ
    J Biol Chem; 2015 Feb; 290(9):5592-605. PubMed ID: 25561726
    [TBL] [Abstract][Full Text] [Related]  

  • 17. mTOR kinase domain phosphorylation promotes mTORC1 signaling, cell growth, and cell cycle progression.
    Ekim B; Magnuson B; Acosta-Jaquez HA; Keller JA; Feener EP; Fingar DC
    Mol Cell Biol; 2011 Jul; 31(14):2787-801. PubMed ID: 21576368
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Up-regulation of the mammalian target of rapamycin complex 1 subunit Raptor by aldosterone induces abnormal pulmonary artery smooth muscle cell survival patterns to promote pulmonary arterial hypertension.
    Aghamohammadzadeh R; Zhang YY; Stephens TE; Arons E; Zaman P; Polach KJ; Matar M; Yung LM; Yu PB; Bowman FP; Opotowsky AR; Waxman AB; Loscalzo J; Leopold JA; Maron BA
    FASEB J; 2016 Jul; 30(7):2511-27. PubMed ID: 27006450
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ERK1/2 phosphorylate Raptor to promote Ras-dependent activation of mTOR complex 1 (mTORC1).
    Carriere A; Romeo Y; Acosta-Jaquez HA; Moreau J; Bonneil E; Thibault P; Fingar DC; Roux PP
    J Biol Chem; 2011 Jan; 286(1):567-77. PubMed ID: 21071439
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Phosphorylation of the novel mTOR substrate Unkempt regulates cellular morphogenesis.
    Baskaran P; Mihaylov SR; Vinsland E; Shah K; Granat L; Ultanir SK; Tee AR; Murn J; Bateman JM
    J Biol Chem; 2023 Jan; 299(1):102788. PubMed ID: 36509146
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 22.