BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

206 related articles for article (PubMed ID: 26351364)

  • 1. Xanthine-based KMUP-1 improves HDL via PPARγ/SR-B1, LDL via LDLRs, and HSL via PKA/PKG for hepatic fat loss.
    Kuo KK; Wu BN; Liu CP; Yang TY; Kao LP; Wu JR; Lai WT; Chen IJ
    J Lipid Res; 2015 Nov; 56(11):2070-84. PubMed ID: 26351364
    [TBL] [Abstract][Full Text] [Related]  

  • 2. KMUP-1, a GPCR Modulator, Attenuates Triglyceride Accumulation Involved MAPKs/Akt/PPARγ and PKA/PKG/HSL Signaling in 3T3-L1 Preadipocytes.
    Liu CP; Chau PC; Chang CT; An LM; Yeh JL; Chen IJ; Wu BN
    Molecules; 2018 Sep; 23(10):. PubMed ID: 30249030
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Theophylline-Based KMUP-1 Improves Steatohepatitis via MMP-9/IL-10 and Lipolysis via HSL/p-HSL in Obese Mice.
    Wu BN; Kuo KK; Chen YH; Chang CT; Huang HT; Chai CY; Dai ZK; Chen IJ
    Int J Mol Sci; 2016 Aug; 17(8):. PubMed ID: 27548140
    [TBL] [Abstract][Full Text] [Related]  

  • 4. NO donor KMUP-1 improves hepatic ischemia-reperfusion and hypoxic cell injury by inhibiting oxidative stress and pro-inflammatory signaling.
    Kuo KK; Wu BN; Chiu EY; Tseng CJ; Yeh JL; Liu CP; Chai CY; Chen IJ
    Int J Immunopathol Pharmacol; 2013; 26(1):93-106. PubMed ID: 23527712
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The xanthine derivative KMUP-1 inhibits models of pulmonary artery hypertension via increased NO and cGMP-dependent inhibition of RhoA/Rho kinase.
    Chung HH; Dai ZK; Wu BN; Yeh JL; Chai CY; Chu KS; Liu CP; Chen IJ
    Br J Pharmacol; 2010 Jun; 160(4):971-86. PubMed ID: 20590592
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phosphodiesterase inhibitor KMUP-3 displays cardioprotection via protein kinase G and increases cardiac output via G-protein-coupled receptor agonist activity and Ca(2+) sensitization.
    Liu CP; Yeh JL; Liou SF; Wu BN; Chen IJ
    Kaohsiung J Med Sci; 2016 Feb; 32(2):55-67. PubMed ID: 26944323
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of proinflammatory tumor necrosis factor-{alpha}-induced inducible nitric-oxide synthase by xanthine-based 7-[2-[4-(2-chlorobenzene)piperazinyl]ethyl]-1,3-dimethylxanthine (KMUP-1) and 7-[2-[4-(4-nitrobenzene)piperazinyl]ethyl]-1, 3-dimethylxanthine (KMUP-3) in rat trachea: The involvement of soluble guanylate cyclase and protein kinase G.
    Wu BN; Chen CW; Liou SF; Yeh JL; Chung HH; Chen IJ
    Mol Pharmacol; 2006 Sep; 70(3):977-85. PubMed ID: 16754782
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Endothelial nitric oxide synthase-enhancing G-protein coupled receptor antagonist inhibits pulmonary artery hypertension by endothelin-1-dependent and endothelin-1-independent pathways in a monocrotaline model.
    Liu CP; Dai ZK; Huang CH; Yeh JL; Wu BN; Wu JR; Chen IJ
    Kaohsiung J Med Sci; 2014 Jun; 30(6):267-78. PubMed ID: 24835346
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The high-fat high-fructose hamster as an animal model for niacin's biological activities in humans.
    Connolly BA; O'Connell DP; Lamon-Fava S; LeBlanc DF; Kuang YL; Schaefer EJ; Coppage AL; Benedict CR; Kiritsy CP; Bachovchin WW
    Metabolism; 2013 Dec; 62(12):1840-9. PubMed ID: 24035454
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulation of macrophage cholesterol efflux through hydroxymethylglutaryl-CoA reductase inhibition: a role for RhoA in ABCA1-mediated cholesterol efflux.
    Argmann CA; Edwards JY; Sawyez CG; O'Neil CH; Hegele RA; Pickering JG; Huff MW
    J Biol Chem; 2005 Jun; 280(23):22212-21. PubMed ID: 15817453
    [TBL] [Abstract][Full Text] [Related]  

  • 11. KMUP-1, a xanthine derivative, induces relaxation of guinea-pig isolated trachea: the role of the epithelium, cyclic nucleotides and K+ channels.
    Wu BN; Lin RJ; Lo YC; Shen KP; Wang CC; Lin YT; Chen IJ
    Br J Pharmacol; 2004 Aug; 142(7):1105-14. PubMed ID: 15237094
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Propofol up-regulates expression of ABCA1, ABCG1, and SR-B1 through the PPARγ/LXRα signaling pathway in THP-1 macrophage-derived foam cells.
    Ma X; Li SF; Qin ZS; Ye J; Zhao ZL; Fang HH; Yao ZW; Gu MN; Hu YW
    Cardiovasc Pathol; 2015; 24(4):230-5. PubMed ID: 25600616
    [TBL] [Abstract][Full Text] [Related]  

  • 13. cGMP-enhancing- and alpha1A/alpha1D-adrenoceptor blockade-derived inhibition of Rho-kinase by KMUP-1 provides optimal prostate relaxation and epithelial cell anti-proliferation efficacy.
    Liu CM; Lo YC; Wu BN; Wu WJ; Chou YH; Huang CH; An LM; Chen IJ
    Prostate; 2007 Sep; 67(13):1397-410. PubMed ID: 17639498
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A xanthine-based epithelium-dependent airway relaxant KMUP-3 (7-[2-[4-(4-nitrobenzene)piperazinyl]ethyl]-1,3-dimethylxanthine) increases respiratory performance and protects against tumor necrosis factor-alpha-induced tracheal contraction, involving nitric oxide release and expression of cGMP and protein kinase G.
    Lin RJ; Wu BN; Lo YC; An LM; Dai ZK; Lin YT; Tang CS; Chen IJ
    J Pharmacol Exp Ther; 2006 Feb; 316(2):709-17. PubMed ID: 16234412
    [TBL] [Abstract][Full Text] [Related]  

  • 15. KMUP-1 attenuates serum deprivation-induced neurotoxicity in SH-SY5Y cells: roles of PKG, PI3K/Akt and Bcl-2/Bax pathways.
    Hsu YY; Liu CM; Tsai HH; Jong YJ; Chen IJ; Lo YC
    Toxicology; 2010 Jan; 268(1-2):46-54. PubMed ID: 19962417
    [TBL] [Abstract][Full Text] [Related]  

  • 16. NO-releasing xanthine KMUP-1 bonded by simvastatin attenuates bleomycin-induced lung inflammation and delayed fibrosis.
    Liu CP; Kuo MS; Wu BN; Chai CY; Huang HT; Chung PW; Chen IJ
    Pulm Pharmacol Ther; 2014 Feb; 27(1):17-28. PubMed ID: 23518214
    [TBL] [Abstract][Full Text] [Related]  

  • 17. KMUP-1 inhibits H441 lung epithelial cell growth, migration and proinflammation via increased NO/CGMP and inhibited RHO kinase/VEGF signaling pathways.
    Wu BN; Chen HY; Liu CP; Hsu LY; Chen IJ
    Int J Immunopathol Pharmacol; 2011; 24(4):925-39. PubMed ID: 22230399
    [TBL] [Abstract][Full Text] [Related]  

  • 18. KMUP-1 attenuates isoprenaline-induced cardiac hypertrophy in rats through NO/cGMP/PKG and ERK1/2/calcineurin A pathways.
    Yeh JL; Hsu JH; Wu PJ; Liou SF; Liu CP; Chen IJ; Wu BN; Dai ZK; Wu JR
    Br J Pharmacol; 2010 Mar; 159(5):1151-60. PubMed ID: 20132211
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Onion peel extract increases hepatic low-density lipoprotein receptor and ATP-binding cassette transporter A1 messenger RNA expressions in Sprague-Dawley rats fed a high-fat diet.
    Lee SM; Moon J; Do HJ; Chung JH; Lee KH; Cha YJ; Shin MJ
    Nutr Res; 2012 Mar; 32(3):210-7. PubMed ID: 22464808
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Polyphenol-rich black chokeberry (Aronia melanocarpa) extract regulates the expression of genes critical for intestinal cholesterol flux in Caco-2 cells.
    Kim B; Park Y; Wegner CJ; Bolling BW; Lee J
    J Nutr Biochem; 2013 Sep; 24(9):1564-70. PubMed ID: 23517916
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.