These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

125 related articles for article (PubMed ID: 26351917)

  • 1. IsoQC (QPCTL) knock-out mice suggest differential substrate conversion by glutaminyl cyclase isoenzymes.
    Becker A; Eichentopf R; Sedlmeier R; Waniek A; Cynis H; Koch B; Stephan A; Bäuscher C; Kohlmann S; Hoffmann T; Kehlen A; Berg S; Freyse EJ; Osmand A; Plank AC; Roßner S; von Hörsten S; Graubner S; Demuth HU; Schilling S
    Biol Chem; 2016 Jan; 397(1):45-55. PubMed ID: 26351917
    [TBL] [Abstract][Full Text] [Related]  

  • 2. N-terminal pyroglutamate formation in CX3CL1 is essential for its full biologic activity.
    Kehlen A; Haegele M; Böhme L; Cynis H; Hoffmann T; Demuth HU
    Biosci Rep; 2017 Aug; 37(4):. PubMed ID: 28739588
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mouse strain and brain region-specific expression of the glutaminyl cyclases QC and isoQC.
    Höfling C; Indrischek H; Höpcke T; Waniek A; Cynis H; Koch B; Schilling S; Morawski M; Demuth HU; Roßner S; Hartlage-Rübsamen M
    Int J Dev Neurosci; 2014 Aug; 36():64-73. PubMed ID: 24886834
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mammalian glutaminyl cyclases and their isoenzymes have identical enzymatic characteristics.
    Stephan A; Wermann M; von Bohlen A; Koch B; Cynis H; Demuth HU; Schilling S
    FEBS J; 2009 Nov; 276(22):6522-36. PubMed ID: 19804409
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Glutaminyl cyclase knock-out mice exhibit slight hypothyroidism but no hypogonadism: implications for enzyme function and drug development.
    Schilling S; Kohlmann S; Bäuscher C; Sedlmeier R; Koch B; Eichentopf R; Becker A; Cynis H; Hoffmann T; Berg S; Freyse EJ; von Hörsten S; Rossner S; Graubner S; Demuth HU
    J Biol Chem; 2011 Apr; 286(16):14199-208. PubMed ID: 21330373
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Isoglutaminyl cyclase contributes to CCL2-driven neuroinflammation in Alzheimer's disease.
    Hartlage-Rübsamen M; Waniek A; Meissner J; Morawski M; Schilling S; Jäger C; Kleinschmidt M; Cynis H; Kehlen A; Arendt T; Demuth HU; Rossner S
    Acta Neuropathol; 2015 Apr; 129(4):565-83. PubMed ID: 25666182
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Isolation of an isoenzyme of human glutaminyl cyclase: retention in the Golgi complex suggests involvement in the protein maturation machinery.
    Cynis H; Rahfeld JU; Stephan A; Kehlen A; Koch B; Wermann M; Demuth HU; Schilling S
    J Mol Biol; 2008 Jun; 379(5):966-80. PubMed ID: 18486145
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The isoenzyme of glutaminyl cyclase is an important regulator of monocyte infiltration under inflammatory conditions.
    Cynis H; Hoffmann T; Friedrich D; Kehlen A; Gans K; Kleinschmidt M; Rahfeld JU; Wolf R; Wermann M; Stephan A; Haegele M; Sedlmeier R; Graubner S; Jagla W; Müller A; Eichentopf R; Heiser U; Seifert F; Quax PH; de Vries MR; Hesse I; Trautwein D; Wollert U; Berg S; Freyse EJ; Schilling S; Demuth HU
    EMBO Mol Med; 2011 Sep; 3(9):545-58. PubMed ID: 21774078
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of Glutaminyl Cyclases alleviates CCL2-mediated inflammation of non-alcoholic fatty liver disease in mice.
    Cynis H; Kehlen A; Haegele M; Hoffmann T; Heiser U; Fujii M; Shibazaki Y; Yoneyama H; Schilling S; Demuth HU
    Int J Exp Pathol; 2013 Jun; 94(3):217-25. PubMed ID: 23560443
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role of glutaminyl cyclases in thyroid carcinomas.
    Kehlen A; Haegele M; Menge K; Gans K; Immel UD; Hoang-Vu C; Klonisch T; Demuth HU
    Endocr Relat Cancer; 2013 Feb; 20(1):79-90. PubMed ID: 23183267
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of thyrotropin-releasing hormone as hippocampal glutaminyl cyclase substrate in neurons and reactive astrocytes.
    Waniek A; Hartlage-Rübsamen M; Höfling C; Kehlen A; Schilling S; Demuth HU; Roßner S
    Biochim Biophys Acta; 2015 Jan; 1852(1):146-55. PubMed ID: 25446989
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Focal Cerebral Ischemia Induces Expression of Glutaminyl Cyclase along with Downstream Molecular and Cellular Inflammatory Responses.
    Höfling C; Ulrich L; Burghardt S; Donkersloot P; Opitz M; Geissler S; Schilling S; Cynis H; Michalski D; Roßner S
    Cells; 2024 Aug; 13(17):. PubMed ID: 39272984
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Amyloidogenic processing of amyloid precursor protein: evidence of a pivotal role of glutaminyl cyclase in generation of pyroglutamate-modified amyloid-beta.
    Cynis H; Scheel E; Saido TC; Schilling S; Demuth HU
    Biochemistry; 2008 Jul; 47(28):7405-13. PubMed ID: 18570439
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Glutaminyl cyclase contributes to the formation of focal and diffuse pyroglutamate (pGlu)-Aβ deposits in hippocampus via distinct cellular mechanisms.
    Hartlage-Rübsamen M; Morawski M; Waniek A; Jäger C; Zeitschel U; Koch B; Cynis H; Schilling S; Schliebs R; Demuth HU; Rossner S
    Acta Neuropathol; 2011 Jun; 121(6):705-19. PubMed ID: 21301857
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Glutaminyl cyclase in human cortex: correlation with (pGlu)-amyloid-β load and cognitive decline in Alzheimer's disease.
    Morawski M; Schilling S; Kreuzberger M; Waniek A; Jäger C; Koch B; Cynis H; Kehlen A; Arendt T; Hartlage-Rübsamen M; Demuth HU; Roßner S
    J Alzheimers Dis; 2014; 39(2):385-400. PubMed ID: 24164736
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Isolation and characterization of glutaminyl cyclases from Drosophila: evidence for enzyme forms with different subcellular localization.
    Schilling S; Lindner C; Koch B; Wermann M; Rahfeld JU; von Bohlen A; Rudolph T; Reuter G; Demuth HU
    Biochemistry; 2007 Sep; 46(38):10921-30. PubMed ID: 17722885
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of glutaminyl cyclase alters pyroglutamate formation in mammalian cells.
    Cynis H; Schilling S; Bodnár M; Hoffmann T; Heiser U; Saido TC; Demuth HU
    Biochim Biophys Acta; 2006 Oct; 1764(10):1618-25. PubMed ID: 17005457
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Substrate specificity of glutaminyl cyclases from plants and animals.
    Schilling S; Manhart S; Hoffmann T; Ludwig HH; Wasternack C; Demuth HU
    Biol Chem; 2003 Dec; 384(12):1583-92. PubMed ID: 14719800
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Distinct glutaminyl cyclase expression in Edinger-Westphal nucleus, locus coeruleus and nucleus basalis Meynert contributes to pGlu-Abeta pathology in Alzheimer's disease.
    Morawski M; Hartlage-Rübsamen M; Jäger C; Waniek A; Schilling S; Schwab C; McGeer PL; Arendt T; Demuth HU; Rossner S
    Acta Neuropathol; 2010 Aug; 120(2):195-207. PubMed ID: 20383514
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of glutaminyl cyclase prevents pGlu-Abeta formation after intracortical/hippocampal microinjection in vivo/in situ.
    Schilling S; Appl T; Hoffmann T; Cynis H; Schulz K; Jagla W; Friedrich D; Wermann M; Buchholz M; Heiser U; von Hörsten S; Demuth HU
    J Neurochem; 2008 Aug; 106(3):1225-36. PubMed ID: 18627432
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.