BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 26355700)

  • 1. Development of Novel Bioluminescent Sensor to Detect and Discriminate between Vitamin D Receptor Agonists and Antagonists in Living Cells.
    Mano H; Nishikawa M; Yasuda K; Ikushiro S; Saito N; Takano M; Kittaka A; Sakaki T
    Bioconjug Chem; 2015 Oct; 26(10):2038-45. PubMed ID: 26355700
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Novel screening system for high-affinity ligand of heredity vitamin D-resistant rickets-associated vitamin D receptor mutant R274L using bioluminescent sensor.
    Mano H; Nishikawa M; Yasuda K; Ikushiro S; Saito N; Sawada D; Honzawa S; Takano M; Kittaka A; Sakaki T
    J Steroid Biochem Mol Biol; 2017 Mar; 167():61-66. PubMed ID: 27864003
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel split luciferase-based biosensors for evaluation of vitamin D receptor ligands and their application to estimate CYP27B1 activity in living cells.
    Mano H; Ikushiro S; Sakaki T
    J Steroid Biochem Mol Biol; 2018 Oct; 183():221-227. PubMed ID: 30004013
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Development of a highly sensitive in vitro system to detect and discriminate between vitamin D receptor agonists and antagonists based on split-luciferase technique.
    Mano H; Ikushiro S; Saito N; Kittaka A; Sakaki T
    J Steroid Biochem Mol Biol; 2018 Apr; 178():55-59. PubMed ID: 29101064
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel biosensor using split-luciferase for detecting vitamin D receptor ligands based on the interaction between vitamin D receptor and coactivator.
    Mano H; Takano M; Ikushiro S; Kittaka A; Sakaki T
    Biochem Biophys Res Commun; 2018 Oct; 505(2):460-465. PubMed ID: 30268505
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Enhanced coactivator binding and transcriptional activation of mutant vitamin D receptors from patients with hereditary 1,25-dihydroxyvitamin D-resistant rickets by phosphorylation and vitamin D analogs.
    Liu Y; Shen Q; Malloy PJ; Soliman E; Peng X; Kim S; Pike JW; Feldman D; Christakos S
    J Bone Miner Res; 2005 Sep; 20(9):1680-91. PubMed ID: 16059639
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A mixed population of antagonist and agonist binding conformers in a single crystal explains partial agonism against vitamin D receptor: active vitamin D analogues with 22R-alkyl group.
    Anami Y; Itoh T; Egawa D; Yoshimoto N; Yamamoto K
    J Med Chem; 2014 May; 57(10):4351-67. PubMed ID: 24742174
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A new class of vitamin D analogues that induce structural rearrangement of the ligand-binding pocket of the receptor.
    Inaba Y; Yoshimoto N; Sakamaki Y; Nakabayashi M; Ikura T; Tamamura H; Ito N; Shimizu M; Yamamoto K
    J Med Chem; 2009 Mar; 52(5):1438-49. PubMed ID: 19193059
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Fine tuning of agonistic/antagonistic activity for vitamin D receptor by 22-alkyl chain length of ligands: 22S-Hexyl compound unexpectedly restored agonistic activity.
    Anami Y; Sakamaki Y; Itoh T; Inaba Y; Nakabayashi M; Ikura T; Ito N; Yamamoto K
    Bioorg Med Chem; 2015 Nov; 23(22):7274-81. PubMed ID: 26515040
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A unique insertion/substitution in helix H1 of the vitamin D receptor ligand binding domain in a patient with hereditary 1,25-dihydroxyvitamin D-resistant rickets.
    Malloy PJ; Xu R; Cattani A; Reyes mL; Feldman D
    J Bone Miner Res; 2004 Jun; 19(6):1018-24. PubMed ID: 15190891
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Discovery of Nuclear Receptor Ligands and Elucidation of Their Mechanisms of Action.
    Yamamoto K
    Chem Pharm Bull (Tokyo); 2019; 67(7):609-619. PubMed ID: 31257315
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Potent antagonist for the vitamin D receptor: vitamin D analogues with simple side chain structure.
    Sakamaki Y; Inaba Y; Yoshimoto N; Yamamoto K
    J Med Chem; 2010 Aug; 53(15):5813-26. PubMed ID: 20608741
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Butyl pocket formation in the vitamin D receptor strongly affects the agonistic or antagonistic behavior of ligands.
    Yoshimoto N; Sakamaki Y; Haeta M; Kato A; Inaba Y; Itoh T; Nakabayashi M; Ito N; Yamamoto K
    J Med Chem; 2012 May; 55(9):4373-81. PubMed ID: 22512505
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Apo- and Antagonist-Binding Structures of Vitamin D Receptor Ligand-Binding Domain Revealed by Hybrid Approach Combining Small-Angle X-ray Scattering and Molecular Dynamics.
    Anami Y; Shimizu N; Ekimoto T; Egawa D; Itoh T; Ikeguchi M; Yamamoto K
    J Med Chem; 2016 Sep; 59(17):7888-900. PubMed ID: 27535484
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Vitamin D receptor: key roles in bone mineral pathophysiology, molecular mechanism of action, and novel nutritional ligands.
    Jurutka PW; Bartik L; Whitfield GK; Mathern DR; Barthel TK; Gurevich M; Hsieh JC; Kaczmarska M; Haussler CA; Haussler MR
    J Bone Miner Res; 2007 Dec; 22 Suppl 2():V2-10. PubMed ID: 18290715
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Superagonistic action of 14-epi-analogs of 1,25-dihydroxyvitamin D explained by vitamin D receptor-coactivator interaction.
    Eelen G; Verlinden L; Rochel N; Claessens F; De Clercq P; Vandewalle M; Tocchini-Valentini G; Moras D; Bouillon R; Verstuyf A
    Mol Pharmacol; 2005 May; 67(5):1566-73. PubMed ID: 15728261
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hereditary 1,25-dihydroxyvitamin D resistant rickets due to a mutation causing multiple defects in vitamin D receptor function.
    Malloy PJ; Xu R; Peng L; Peleg S; Al-Ashwal A; Feldman D
    Endocrinology; 2004 Nov; 145(11):5106-14. PubMed ID: 15308610
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 25-Dehydro-1alpha-hydroxyvitamin D3-26,23S-lactone antagonizes the nuclear vitamin D receptor by mediating a unique noncovalent conformational change.
    Bula CM; Bishop JE; Ishizuka S; Norman AW
    Mol Endocrinol; 2000 Nov; 14(11):1788-96. PubMed ID: 11075812
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Critical role of helix 12 of the vitamin D(3) receptor for the partial agonism of carboxylic ester antagonists.
    Väisänen S; Peräkylä M; Kärkkäinen JI; Steinmeyer A; Carlberg C
    J Mol Biol; 2002 Jan; 315(2):229-38. PubMed ID: 11779241
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SRC2-3 binds to vitamin D receptor with high sensitivity and strong affinity.
    Egawa D; Itoh T; Kato A; Kataoka S; Anami Y; Yamamoto K
    Bioorg Med Chem; 2017 Jan; 25(2):568-574. PubMed ID: 27890450
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.