265 related articles for article (PubMed ID: 26357462)
21. Discovery of new druggable sites in the anti-cholesterol target HMG-CoA reductase by computational alanine scanning mutagenesis.
Gesto DS; Cerqueira NM; Ramos MJ; Fernandes PA
J Mol Model; 2014 Apr; 20(4):2178. PubMed ID: 24671303
[TBL] [Abstract][Full Text] [Related]
22. Proteopedia entry: HMG-CoA reductase.
Canner D
Biochem Mol Biol Educ; 2011; 39(1):64. PubMed ID: 21433257
[No Abstract] [Full Text] [Related]
23. IAF, QGF, and QDF Peptides Exhibit Cholesterol-Lowering Activity through a Statin-like HMG-CoA Reductase Regulation Mechanism: In Silico and In Vitro Approach.
Silva M; Philadelpho B; Santos J; Souza V; Souza C; Santiago V; Silva J; Souza C; Azeredo F; Castilho M; Cilli E; Ferreira E
Int J Mol Sci; 2021 Oct; 22(20):. PubMed ID: 34681729
[TBL] [Abstract][Full Text] [Related]
24. Three-dimensional quantitative structure (3-D QSAR) activity relationship studies on imidazolyl and N-pyrrolyl heptenoates as 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR) inhibitors by comparative molecular similarity indices analysis (CoMSIA).
Thilagavathi R; Kumar R; Aparna V; Sobhia ME; Gopalakrishnan B; Chakraborti AK
Bioorg Med Chem Lett; 2005 Feb; 15(4):1027-32. PubMed ID: 15686906
[TBL] [Abstract][Full Text] [Related]
25. Structure-based design and screen of novel inhibitors for class II 3-hydroxy-3-methylglutaryl coenzyme A reductase from Streptococcus pneumoniae.
Li D; Gui J; Li Y; Feng L; Han X; Sun Y; Sun T; Chen Z; Cao Y; Zhang Y; Zhou L; Hu X; Ren Y; Wan J
J Chem Inf Model; 2012 Jul; 52(7):1833-41. PubMed ID: 22725250
[TBL] [Abstract][Full Text] [Related]
26. Cloning, Purification, and Characterization of the Catalytic C-Terminal Domain of the Human 3-Hydroxy-3-methyl glutaryl-CoA Reductase: An Effective, Fast, and Easy Method for Testing Hypocholesterolemic Compounds.
Curcio R; Aiello D; Vozza A; Muto L; Martello E; Cappello AR; Capobianco L; Fiermonte G; Siciliano C; Napoli A; Dolce V
Mol Biotechnol; 2020 Feb; 62(2):119-131. PubMed ID: 31758489
[TBL] [Abstract][Full Text] [Related]
27. Thermodynamic and structure guided design of statin based inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase.
Sarver RW; Bills E; Bolton G; Bratton LD; Caspers NL; Dunbar JB; Harris MS; Hutchings RH; Kennedy RM; Larsen SD; Pavlovsky A; Pfefferkorn JA; Bainbridge G
J Med Chem; 2008 Jul; 51(13):3804-13. PubMed ID: 18540668
[TBL] [Abstract][Full Text] [Related]
28. In vitro and in silico studies of 3-hydroxy-3-methyl-glutaryl coenzyme A reductase inhibitory activity of the cowpea Gln-Asp-Phe peptide.
Silva MBCE; Souza CADC; Philadelpho BO; Cunha MMND; Batista FPR; Silva JRD; Druzian JI; Castilho MS; Cilli EM; Ferreira ES
Food Chem; 2018 Sep; 259():270-277. PubMed ID: 29680054
[TBL] [Abstract][Full Text] [Related]
29. DOX: A new computational protocol for accurate prediction of the protein-ligand binding structures.
Rao L; Chi B; Ren Y; Li Y; Xu X; Wan J
J Comput Chem; 2016 Jan; 37(3):336-44. PubMed ID: 26459237
[TBL] [Abstract][Full Text] [Related]
30. Review of synthesis, biological assay, and QSAR studies of HMGR inhibitors.
García I; Fall Y; Gómez G
Curr Top Med Chem; 2012; 12(8):895-919. PubMed ID: 22352916
[TBL] [Abstract][Full Text] [Related]
31. Is there a relationship between 3-hydroxy-3-methylglutaryl coenzyme a reductase activity and forebrain pathology in the PKU mouse?
Shefer S; Tint GS; Jean-Guillaume D; Daikhin E; Kendler A; Nguyen LB; Yudkoff M; Dyer CA
J Neurosci Res; 2000 Sep; 61(5):549-63. PubMed ID: 10956425
[TBL] [Abstract][Full Text] [Related]
32. Discovery and quantitative structure-activity relationship study of lepidopteran HMG-CoA reductase inhibitors as selective insecticides.
Zang YY; Li YM; Yin Y; Chen SS; Kai ZP
Pest Manag Sci; 2017 Sep; 73(9):1944-1952. PubMed ID: 28247468
[TBL] [Abstract][Full Text] [Related]
33. Crystal structure of archaeal HMG-CoA reductase: insights into structural changes of the C-terminal helix of the class-I enzyme.
Vögeli B; Shima S; Erb TJ; Wagner T
FEBS Lett; 2019 Mar; 593(5):543-553. PubMed ID: 30702149
[TBL] [Abstract][Full Text] [Related]
34. Antihyperlipidemic studies of newly synthesized phenolic derivatives: in silico and in vivo approaches.
Aqeel MT; Ur-Rahman N; Khan AU; Ashraf Z; Latif M; Rafique H; Rasheed U
Drug Des Devel Ther; 2018; 12():2443-2453. PubMed ID: 30127594
[TBL] [Abstract][Full Text] [Related]
35. Explication of interactions between HMGCR isoform 2 and various statins through In silico modeling and docking.
Karthik MV; Satya Deepak MV; Shukla P
Comput Biol Med; 2012 Feb; 42(2):156-63. PubMed ID: 22177940
[TBL] [Abstract][Full Text] [Related]
36. Characterization of an HMG-CoA reductase from Listeria monocytogenes that exhibits dual coenzyme specificity.
Theivagt AE; Amanti EN; Beresford NJ; Tabernero L; Friesen JA
Biochemistry; 2006 Dec; 45(48):14397-406. PubMed ID: 17128979
[TBL] [Abstract][Full Text] [Related]
37. Bioactivities of
Guedes L; Reis PBPS; Machuqueiro M; Ressaissi A; Pacheco R; Serralheiro ML
Molecules; 2019 Oct; 24(20):. PubMed ID: 31652501
[No Abstract] [Full Text] [Related]
38. Inhibitory effect of novel diallyldisulfide analogs on HMG-CoA reductase expression in hypercholesterolemic rats: CREB as a potential upstream target.
Rai SK; Sharma M; Tiwari M
Life Sci; 2009 Jul; 85(5-6):211-9. PubMed ID: 19523964
[TBL] [Abstract][Full Text] [Related]
39. Statins: An undesirable class of aquatic contaminants?
Santos MM; Ruivo R; Lopes-Marques M; Torres T; de los Santos CB; Castro LF; Neuparth T
Aquat Toxicol; 2016 May; 174():1-9. PubMed ID: 26896816
[TBL] [Abstract][Full Text] [Related]
40. In-silico HMG-CoA reductase-inhibitory and in-vivo anti-lipidaemic/anticancer effects of carotenoids from Spondias mombin.
Metibemu DS; Akinloye OA; Akamo AJ; Okoye JO; Omotuyi IO
J Pharm Pharmacol; 2021 Sep; 73(10):1377-1386. PubMed ID: 34343336
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]