BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

302 related articles for article (PubMed ID: 26358247)

  • 1. Frontotemporal dementia caused by CHMP2B mutation is characterised by neuronal lysosomal storage pathology.
    Clayton EL; Mizielinska S; Edgar JR; Nielsen TT; Marshall S; Norona FE; Robbins M; Damirji H; Holm IE; Johannsen P; Nielsen JE; Asante EA; Collinge J; ; Isaacs AM
    Acta Neuropathol; 2015 Oct; 130(4):511-23. PubMed ID: 26358247
    [TBL] [Abstract][Full Text] [Related]  

  • 2. TMEM106B, a frontotemporal lobar dementia (FTLD) modifier, associates with FTD-3-linked CHMP2B, a complex of ESCRT-III.
    Jun MH; Han JH; Lee YK; Jang DJ; Kaang BK; Lee JA
    Mol Brain; 2015 Dec; 8():85. PubMed ID: 26651479
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A novel synaptopathy-defective synaptic vesicle protein trafficking in the mutant CHMP2B mouse model of frontotemporal dementia.
    Clayton EL; Bonnycastle K; Isaacs AM; Cousin MA; Schorge S
    J Neurochem; 2022 Feb; 160(3):412-425. PubMed ID: 34855215
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Early microgliosis precedes neuronal loss and behavioural impairment in mice with a frontotemporal dementia-causing CHMP2B mutation.
    Clayton EL; Mancuso R; Nielsen TT; Mizielinska S; Holmes H; Powell N; Norona F; Larsen JO; Milioto C; Wilson KM; Lythgoe MF; Ourselin S; Nielsen JE; Johannsen P; Holm I; Collinge J; ; Oliver PL; Gomez-Nicola D; Isaacs AM
    Hum Mol Genet; 2017 Mar; 26(5):873-887. PubMed ID: 28093491
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Frontotemporal dementia causative CHMP2B impairs neuronal endolysosomal traffic-rescue by TMEM106B knockdown.
    Clayton EL; Milioto C; Muralidharan B; Norona FE; Edgar JR; Soriano A; Jafar-Nejad P; Rigo F; Collinge J; Isaacs AM
    Brain; 2018 Dec; 141(12):3428-3442. PubMed ID: 30496365
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Disruption of endocytic trafficking in frontotemporal dementia with CHMP2B mutations.
    Urwin H; Authier A; Nielsen JE; Metcalf D; Powell C; Froud K; Malcolm DS; Holm I; Johannsen P; Brown J; Fisher EM; van der Zee J; Bruyland M; ; Van Broeckhoven C; Collinge J; Brandner S; Futter C; Isaacs AM
    Hum Mol Genet; 2010 Jun; 19(11):2228-38. PubMed ID: 20223751
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Alteration of microglial metabolism and inflammatory profile contributes to neurotoxicity in a hiPSC-derived microglia model of frontotemporal dementia 3.
    Haukedal H; Syshøj Lorenzen S; Winther Westi E; Corsi GI; Gadekar VP; McQuade A; Davtyan H; Doncheva NT; Schmid B; Chandrasekaran A; Seemann SE; Cirera S; Blurton-Jones M; Meyer M; Gorodkin J; Aldana BI; Freude K
    Brain Behav Immun; 2023 Oct; 113():353-373. PubMed ID: 37543250
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A transgenic mouse expressing CHMP2Bintron5 mutant in neurons develops histological and behavioural features of amyotrophic lateral sclerosis and frontotemporal dementia.
    Vernay A; Therreau L; Blot B; Risson V; Dirrig-Grosch S; Waegaert R; Lequeu T; Sellal F; Schaeffer L; Sadoul R; Loeffler JP; René F
    Hum Mol Genet; 2016 Aug; 25(15):3341-3360. PubMed ID: 27329763
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Longitudinal transcriptomic analysis of altered pathways in a CHMP2B
    Waegaert R; Dirrig-Grosch S; Parisot F; Keime C; Henriques A; Loeffler JP; René F
    Neurobiol Dis; 2020 Mar; 136():104710. PubMed ID: 31837425
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The role of CHMP2B
    Krasniak CS; Ahmad ST
    Brain Res; 2016 Oct; 1649(Pt B):151-157. PubMed ID: 26972529
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Frontotemporal dementia caused by CHMP2B mutations.
    Isaacs AM; Johannsen P; Holm I; Nielsen JE;
    Curr Alzheimer Res; 2011 May; 8(3):246-51. PubMed ID: 21222599
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Neuroprotective activity of ursodeoxycholic acid in CHMP2B
    West RJH; Ugbode C; Fort-Aznar L; Sweeney ST
    Neurobiol Dis; 2020 Oct; 144():105047. PubMed ID: 32801000
    [TBL] [Abstract][Full Text] [Related]  

  • 13. TMEM106B and ApoE polymorphisms in CHMP2B-mediated frontotemporal dementia (FTD-3).
    Rostgaard N; Roos P; Budtz-Jørgensen E; Johannsen P; Waldemar G; Nørremølle A; Lindquist SG; Gydesen S; Brown JM; Collinge J; Isaacs AM; ; Nielsen TT; Nielsen JE
    Neurobiol Aging; 2017 Nov; 59():221.e1-221.e7. PubMed ID: 28888721
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CHMP2B mutants linked to frontotemporal dementia impair maturation of dendritic spines.
    Belly A; Bodon G; Blot B; Bouron A; Sadoul R; Goldberg Y
    J Cell Sci; 2010 Sep; 123(Pt 17):2943-54. PubMed ID: 20699355
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Network analysis of the progranulin-deficient mouse brain proteome reveals pathogenic mechanisms shared in human frontotemporal dementia caused by GRN mutations.
    Huang M; Modeste E; Dammer E; Merino P; Taylor G; Duong DM; Deng Q; Holler CJ; Gearing M; Dickson D; Seyfried NT; Kukar T
    Acta Neuropathol Commun; 2020 Oct; 8(1):163. PubMed ID: 33028409
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular Genetics of Frontotemporal Dementia Elucidated by
    Vandal SE; Zheng X; Ahmad ST
    Int J Mol Sci; 2018 Jun; 19(6):. PubMed ID: 29890743
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Progranulin Gene Therapy Improves Lysosomal Dysfunction and Microglial Pathology Associated with Frontotemporal Dementia and Neuronal Ceroid Lipofuscinosis.
    Arrant AE; Onyilo VC; Unger DE; Roberson ED
    J Neurosci; 2018 Feb; 38(9):2341-2358. PubMed ID: 29378861
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Absence of FUS-immunoreactive pathology in frontotemporal dementia linked to chromosome 3 (FTD-3) caused by mutation in the CHMP2B gene.
    Holm IE; Isaacs AM; Mackenzie IR
    Acta Neuropathol; 2009 Nov; 118(5):719-20. PubMed ID: 19844732
    [No Abstract]   [Full Text] [Related]  

  • 19. Partial Tmem106b reduction does not correct abnormalities due to progranulin haploinsufficiency.
    Arrant AE; Nicholson AM; Zhou X; Rademakers R; Roberson ED
    Mol Neurodegener; 2018 Jun; 13(1):32. PubMed ID: 29929528
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A novel splice-site mutation in CHMP2B associated with frontotemporal dementia: The first report from China and literature review.
    Li C; Wen Y; Zhao M; Wang Y; Li P; Wang L; Wang S
    Mol Genet Genomic Med; 2023 Aug; 11(8):e2222. PubMed ID: 37272767
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.