These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

178 related articles for article (PubMed ID: 26358280)

  • 41. PPM1D exerts its oncogenic properties in human pancreatic cancer through multiple mechanisms.
    Wu B; Guo BM; Kang J; Deng XZ; Fan YB; Zhang XP; Ai KX
    Apoptosis; 2016 Mar; 21(3):365-78. PubMed ID: 26714478
    [TBL] [Abstract][Full Text] [Related]  

  • 42. PPM1D activity promotes cellular transformation by preventing senescence and cell death.
    Stoyanov M; Martinikova AS; Matejkova K; Horackova K; Zemankova P; Burdova K; Zemanova Z; Kleiblova P; Kleibl Z; Macurek L
    Oncogene; 2024 Oct; 43(42):3081-3093. PubMed ID: 39237765
    [TBL] [Abstract][Full Text] [Related]  

  • 43. The p53-induced oncogenic phosphatase PPM1D interacts with uracil DNA glycosylase and suppresses base excision repair.
    Lu X; Bocangel D; Nannenga B; Yamaguchi H; Appella E; Donehower LA
    Mol Cell; 2004 Aug; 15(4):621-34. PubMed ID: 15327777
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Bufotalin from Venenum Bufonis inhibits growth of multidrug resistant HepG2 cells through G2/M cell cycle arrest and apoptosis.
    Zhang DM; Liu JS; Tang MK; Yiu A; Cao HH; Jiang L; Chan JY; Tian HY; Fung KP; Ye WC
    Eur J Pharmacol; 2012 Oct; 692(1-3):19-28. PubMed ID: 22841670
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Synergistic Antiproliferative Effects of a New Cucurbitacin B Derivative and Chemotherapy Drugs on Lung Cancer Cell Line A549.
    Marostica LL; Silva IT; Kratz JM; Persich L; Geller FC; Lang KL; Caro MS; Durán FJ; Schenkel EP; Simões CM
    Chem Res Toxicol; 2015 Oct; 28(10):1949-60. PubMed ID: 26372186
    [TBL] [Abstract][Full Text] [Related]  

  • 46. The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop.
    Lu X; Ma O; Nguyen TA; Jones SN; Oren M; Donehower LA
    Cancer Cell; 2007 Oct; 12(4):342-54. PubMed ID: 17936559
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Protein phosphatase 2A interacts with Chk2 and regulates phosphorylation at Thr-68 after cisplatin treatment of human ovarian cancer cells.
    Liang X; Reed E; Yu JJ
    Int J Mol Med; 2006 May; 17(5):703-8. PubMed ID: 16596250
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Inactivation of the Wip1 phosphatase inhibits mammary tumorigenesis through p38 MAPK-mediated activation of the p16(Ink4a)-p19(Arf) pathway.
    Bulavin DV; Phillips C; Nannenga B; Timofeev O; Donehower LA; Anderson CW; Appella E; Fornace AJ
    Nat Genet; 2004 Apr; 36(4):343-50. PubMed ID: 14991053
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Benzopyran derivative CDRI-85/287 induces G2-M arrest in estrogen receptor-positive breast cancer cells via modulation of estrogen receptors α- and β-mediated signaling, in parallel to EGFR signaling and suppresses the growth of tumor xenograft.
    Saxena R; Fatima I; Chandra V; Blesson CS; Kharkwal G; Hussain MK; Hajela K; Roy BG; Dwivedi A
    Steroids; 2013 Nov; 78(11):1071-86. PubMed ID: 23891847
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Chk1 and Wee1 control genotoxic-stress induced G2-M arrest in melanoma cells.
    Vera J; Raatz Y; Wolkenhauer O; Kottek T; Bhattacharya A; Simon JC; Kunz M
    Cell Signal; 2015 May; 27(5):951-60. PubMed ID: 25683911
    [TBL] [Abstract][Full Text] [Related]  

  • 51. PPM1D gene amplification and overexpression in breast cancer: a qRT-PCR and chromogenic in situ hybridization study.
    Lambros MB; Natrajan R; Geyer FC; Lopez-Garcia MA; Dedes KJ; Savage K; Lacroix-Triki M; Jones RL; Lord CJ; Linardopoulos S; Ashworth A; Reis-Filho JS
    Mod Pathol; 2010 Oct; 23(10):1334-45. PubMed ID: 20543821
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Zoledronic acid in combination with serine/threonine phosphatase inhibitors induces enhanced cytotoxicity and apoptosis in hormone-refractory prostate cancer cell lines by decreasing the activities of PP1 and PP2A.
    Cirak Y; Varol U; Atmaca H; Kisim A; Sezgin C; Karabulut B; Uzunoglu S; Uslu R; Karaca B
    BJU Int; 2012 Dec; 110(11 Pt C):E1147-54. PubMed ID: 22882676
    [TBL] [Abstract][Full Text] [Related]  

  • 53. WIP1 phosphatase at the crossroads of cancer and aging.
    Le Guezennec X; Bulavin DV
    Trends Biochem Sci; 2010 Feb; 35(2):109-14. PubMed ID: 19879149
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Medulloblastomas overexpress the p53-inactivating oncogene WIP1/PPM1D.
    Castellino RC; De Bortoli M; Lu X; Moon SH; Nguyen TA; Shepard MA; Rao PH; Donehower LA; Kim JY
    J Neurooncol; 2008 Feb; 86(3):245-56. PubMed ID: 17932621
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Sodium cantharidate induces Apoptosis in breast cancer cells by regulating energy metabolism via the protein phosphatase 5-p53 axis.
    Pang JL; Huang FH; Zhang YH; Wu Y; Ge XM; Li S; Li X
    Toxicol Appl Pharmacol; 2021 Nov; 430():115726. PubMed ID: 34537213
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Optimization of a cyclic peptide inhibitor of Ser/Thr phosphatase PPM1D (Wip1).
    Hayashi R; Tanoue K; Durell SR; Chatterjee DK; Jenkins LM; Appella DH; Appella E
    Biochemistry; 2011 May; 50(21):4537-49. PubMed ID: 21528848
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Anti-Colon Cancer Effects of 6-Shogaol Through G2/M Cell Cycle Arrest by p53/p21-cdc2/cdc25A Crosstalk.
    Qi LW; Zhang Z; Zhang CF; Anderson S; Liu Q; Yuan CS; Wang CZ
    Am J Chin Med; 2015; 43(4):743-56. PubMed ID: 26119958
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Akt confers cisplatin chemoresistance in human gynecological carcinoma cells by modulating PPM1D stability.
    Ali AY; Kim JY; Pelletier JF; Vanderhyden BC; Bachvarov DR; Tsang BK
    Mol Carcinog; 2015 Nov; 54(11):1301-14. PubMed ID: 25154814
    [TBL] [Abstract][Full Text] [Related]  

  • 59. 12-Deoxyphorbol 13-palmitate mediated cell growth inhibition, G2-M cell cycle arrest and apoptosis in BGC823 cells.
    Xu HY; Chen ZW; Li H; Zhou L; Liu F; Lv YY; Liu JC
    Eur J Pharmacol; 2013 Jan; 700(1-3):13-22. PubMed ID: 23220710
    [TBL] [Abstract][Full Text] [Related]  

  • 60. PPM1D is a potential therapeutic target in ovarian clear cell carcinomas.
    Tan DS; Lambros MB; Rayter S; Natrajan R; Vatcheva R; Gao Q; Marchiò C; Geyer FC; Savage K; Parry S; Fenwick K; Tamber N; Mackay A; Dexter T; Jameson C; McCluggage WG; Williams A; Graham A; Faratian D; El-Bahrawy M; Paige AJ; Gabra H; Gore ME; Zvelebil M; Lord CJ; Kaye SB; Ashworth A; Reis-Filho JS
    Clin Cancer Res; 2009 Apr; 15(7):2269-80. PubMed ID: 19293255
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.