BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

160 related articles for article (PubMed ID: 26358777)

  • 1. Two retinal dystrophy-associated missense mutations in GUCA1A with distinct molecular properties result in a similar aberrant regulation of the retinal guanylate cyclase.
    Marino V; Scholten A; Koch KW; Dell'Orco D
    Hum Mol Genet; 2015 Dec; 24(23):6653-66. PubMed ID: 26358777
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A novel p.(Glu111Val) missense mutation in GUCA1A associated with cone-rod dystrophy leads to impaired calcium sensing and perturbed second messenger homeostasis in photoreceptors.
    Marino V; Dal Cortivo G; Oppici E; Maltese PE; D'Esposito F; Manara E; Ziccardi L; Falsini B; Magli A; Bertelli M; Dell'Orco D
    Hum Mol Genet; 2018 Dec; 27(24):4204-4217. PubMed ID: 30184081
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Constitutive Activation of Guanylate Cyclase by the G86R GCAP1 Variant Is Due to "Locking" Cation-π Interactions that Impair the Activator-to-Inhibitor Structural Transition.
    Abbas S; Marino V; Bielefeld L; Koch KW; Dell'Orco D
    Int J Mol Sci; 2020 Jan; 21(3):. PubMed ID: 31979372
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Missense mutations affecting Ca
    Dal Cortivo G; Marino V; Bonì F; Milani M; Dell'Orco D
    Biochim Biophys Acta Mol Cell Res; 2020 Oct; 1867(10):118794. PubMed ID: 32650103
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A G86R mutation in the calcium-sensor protein GCAP1 alters regulation of retinal guanylyl cyclase and causes dominant cone-rod degeneration.
    Peshenko IV; Cideciyan AV; Sumaroka A; Olshevskaya EV; Scholten A; Abbas S; Koch KW; Jacobson SG; Dizhoor AM
    J Biol Chem; 2019 Mar; 294(10):3476-3488. PubMed ID: 30622141
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Impaired Ca
    Marino V; Dal Cortivo G; Maltese PE; Placidi G; De Siena E; Falsini B; Bertelli M; Dell'Orco D
    Int J Mol Sci; 2021 Apr; 22(8):. PubMed ID: 33919796
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Normal GCAPs partly compensate for altered cGMP signaling in retinal dystrophies associated with mutations in GUCA1A.
    Dell'Orco D; Dal Cortivo G
    Sci Rep; 2019 Dec; 9(1):20105. PubMed ID: 31882816
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A Novel
    Biasi A; Marino V; Dal Cortivo G; Maltese PE; Modarelli AM; Bertelli M; Colombo L; Dell'Orco D
    Int J Mol Sci; 2021 Oct; 22(19):. PubMed ID: 34639157
    [TBL] [Abstract][Full Text] [Related]  

  • 9. GCAP1 mutations associated with autosomal dominant cone dystrophy.
    Jiang L; Baehr W
    Adv Exp Med Biol; 2010; 664():273-82. PubMed ID: 20238026
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The dimerization domain in outer segment guanylate cyclase is a Ca²⁺-sensitive control switch module.
    Zägel P; Dell'Orco D; Koch KW
    Biochemistry; 2013 Jul; 52(30):5065-74. PubMed ID: 23815670
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Calcium binding, structural stability and guanylate cyclase activation in GCAP1 variants associated with human cone dystrophy.
    Dell'Orco D; Behnen P; Linse S; Koch KW
    Cell Mol Life Sci; 2010 Mar; 67(6):973-84. PubMed ID: 20213926
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutations in the GUCA1A gene involved in hereditary cone dystrophies impair calcium-mediated regulation of guanylate cyclase.
    Kitiratschky VB; Behnen P; Kellner U; Heckenlively JR; Zrenner E; Jägle H; Kohl S; Wissinger B; Koch KW
    Hum Mutat; 2009 Aug; 30(8):E782-96. PubMed ID: 19459154
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Neuronal Calcium Sensor GCAP1 Encoded by
    Abbas S; Marino V; Weisschuh N; Kieninger S; Solaki M; Dell'Orco D; Koch KW
    ACS Chem Neurosci; 2020 May; 11(10):1458-1470. PubMed ID: 32298085
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural effects of Mg²⁺ on the regulatory states of three neuronal calcium sensors operating in vertebrate phototransduction.
    Marino V; Sulmann S; Koch KW; Dell'Orco D
    Biochim Biophys Acta; 2015 Sep; 1853(9):2055-65. PubMed ID: 25447547
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A novel mutation (I143NT) in guanylate cyclase-activating protein 1 (GCAP1) associated with autosomal dominant cone degeneration.
    Nishiguchi KM; Sokal I; Yang L; Roychowdhury N; Palczewski K; Berson EL; Dryja TP; Baehr W
    Invest Ophthalmol Vis Sci; 2004 Nov; 45(11):3863-70. PubMed ID: 15505030
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Molecular properties of human guanylate cyclase-activating protein 2 (GCAP2) and its retinal dystrophy-associated variant G157R.
    Avesani A; Marino V; Zanzoni S; Koch KW; Dell'Orco D
    J Biol Chem; 2021; 296():100619. PubMed ID: 33812995
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Dysfunction of cGMP signalling in photoreceptors by a macular dystrophy-related mutation in the calcium sensor GCAP1.
    Vocke F; Weisschuh N; Marino V; Malfatti S; Jacobson SG; Reiff CM; Dell'Orco D; Koch KW
    Hum Mol Genet; 2017 Jan; 26(1):133-144. PubMed ID: 28025326
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structure of Guanylyl Cyclase Activator Protein 1 (GCAP1) Mutant V77E in a Ca2+-free/Mg2+-bound Activator State.
    Lim S; Peshenko IV; Olshevskaya EV; Dizhoor AM; Ames JB
    J Biol Chem; 2016 Feb; 291(9):4429-41. PubMed ID: 26703466
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Calcium-myristoyl Tug is a new mechanism for intramolecular tuning of calcium sensitivity and target enzyme interaction for guanylyl cyclase-activating protein 1: dynamic connection between N-fatty acyl group and EF-hand controls calcium sensitivity.
    Peshenko IV; Olshevskaya EV; Lim S; Ames JB; Dizhoor AM
    J Biol Chem; 2012 Apr; 287(17):13972-84. PubMed ID: 22383530
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of target binding site in photoreceptor guanylyl cyclase-activating protein 1 (GCAP1).
    Peshenko IV; Olshevskaya EV; Lim S; Ames JB; Dizhoor AM
    J Biol Chem; 2014 Apr; 289(14):10140-54. PubMed ID: 24567338
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.