BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

91 related articles for article (PubMed ID: 26370130)

  • 21. DRoP: a water analysis program identifies Ras-GTP-specific pathway of communication between membrane-interacting regions and the active site.
    Kearney BM; Johnson CW; Roberts DM; Swartz P; Mattos C
    J Mol Biol; 2014 Feb; 426(3):611-29. PubMed ID: 24189050
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Analysis of GTPases carrying hydrophobic amino acid substitutions in lieu of the catalytic glutamine: implications for GTP hydrolysis.
    Mishra R; Gara SK; Mishra S; Prakash B
    Proteins; 2005 May; 59(2):332-8. PubMed ID: 15726588
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Amino acid 61 is a determinant of sensitivity of rap proteins to the ras GTPase activating protein.
    Hart PA; Marshall CJ
    Oncogene; 1990 Jul; 5(7):1099-101. PubMed ID: 2115644
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Quantitative Measurement of Intrinsic GTP Hydrolysis for Carcinogenic Glutamine 61 Mutants in H-Ras.
    Novelli ET; First JT; Webb LJ
    Biochemistry; 2018 Nov; 57(44):6356-6366. PubMed ID: 30339365
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The arginine finger of RasGAP helps Gln-61 align the nucleophilic water in GAP-stimulated hydrolysis of GTP.
    Resat H; Straatsma TP; Dixon DA; Miller JH
    Proc Natl Acad Sci U S A; 2001 May; 98(11):6033-8. PubMed ID: 11371635
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Structural analysis of the Ras-like G protein MglA and its cognate GAP MglB and implications for bacterial polarity.
    Miertzschke M; Koerner C; Vetter IR; Keilberg D; Hot E; Leonardy S; Søgaard-Andersen L; Wittinghofer A
    EMBO J; 2011 Aug; 30(20):4185-97. PubMed ID: 21847100
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Molecular dynamics simulations of Gly-12-->Val mutant of p21(ras): dynamic inhibition mechanism.
    Futatsugi N; Tsuda M
    Biophys J; 2001 Dec; 81(6):3483-8. PubMed ID: 11721009
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Dissection of the GTPase mechanism of Ras protein by MD analysis of Ras mutants.
    Friedman ZY; Devary Y
    Proteins; 2005 May; 59(3):528-33. PubMed ID: 15789417
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Role of the arginine finger in Ras.RasGAP revealed by QM/MM calculations.
    te Heesen H; Gerwert K; Schlitter J
    FEBS Lett; 2007 Dec; 581(29):5677-84. PubMed ID: 18022389
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Mechanistic analysis of the observed linear free energy relationships in p21ras and related systems.
    Schweins T; Warshel A
    Biochemistry; 1996 Nov; 35(45):14232-43. PubMed ID: 8916908
    [TBL] [Abstract][Full Text] [Related]  

  • 31. GAP positions catalytic H-Ras residue Q61 for GTP hydrolysis in molecular dynamics simulations, complicating chemical rescue of Ras deactivation.
    Patel LA; Waybright TJ; Stephen AG; Neale C
    Comput Biol Chem; 2023 Jun; 104():107835. PubMed ID: 36893567
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Linear free energy relationships in the intrinsic and GTPase activating protein-stimulated guanosine 5'-triphosphate hydrolysis of p21ras.
    Schweins T; Geyer M; Kalbitzer HR; Wittinghofer A; Warshel A
    Biochemistry; 1996 Nov; 35(45):14225-31. PubMed ID: 8916907
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Real-time in vitro measurement of intrinsic and Ras GAP-mediated GTP hydrolysis.
    Shutes A; Der CJ
    Methods Enzymol; 2006; 407():9-22. PubMed ID: 16757310
    [TBL] [Abstract][Full Text] [Related]  

  • 34. COMBINE analysis of the specificity of binding of Ras proteins to their effectors.
    Tomić S; Bertosa B; Wang T; Wade RC
    Proteins; 2007 May; 67(2):435-47. PubMed ID: 17295314
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Kinetic Mechanism of Formation of Hyperactive Embryonic Ras in Cells.
    Wey M; Lee J; Kim HS; Jeong SS; Kim J; Heo J
    Biochemistry; 2016 Jan; 55(3):543-59. PubMed ID: 26765051
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Transformation efficiency of RasQ61 mutants linked to structural features of the switch regions in the presence of Raf.
    Buhrman G; Wink G; Mattos C
    Structure; 2007 Dec; 15(12):1618-29. PubMed ID: 18073111
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Comparison of nitrophenylethyl and hydroxyphenacyl caging groups.
    Du X; Frei H; Kim SH
    Biopolymers; 2001; 62(3):147-9. PubMed ID: 11343283
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Mechanism of the guanine nucleotide exchange reaction of Ras GTPase--evidence for a GTP/GDP displacement model.
    Zhang B; Zhang Y; Shacter E; Zheng Y
    Biochemistry; 2005 Feb; 44(7):2566-76. PubMed ID: 15709769
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Modeling the mechanisms of biological GTP hydrolysis.
    Carvalho AT; Szeler K; Vavitsas K; Åqvist J; Kamerlin SC
    Arch Biochem Biophys; 2015 Sep; 582():80-90. PubMed ID: 25731854
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Label-free screening of drug-protein interactions by time-resolved Fourier transform infrared spectroscopic assays exemplified by Ras interactions.
    Kötting C; Suveyzdis Y; Bojja RS; Metzler-Nolte N; Gerwert K
    Appl Spectrosc; 2010 Sep; 64(9):967-72. PubMed ID: 20828432
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 5.