487 related articles for article (PubMed ID: 26373282)
1. Frontotemporal dementia-associated N279K tau mutant disrupts subcellular vesicle trafficking and induces cellular stress in iPSC-derived neural stem cells.
Wren MC; Zhao J; Liu CC; Murray ME; Atagi Y; Davis MD; Fu Y; Okano HJ; Ogaki K; Strongosky AJ; Tacik P; Rademakers R; Ross OA; Dickson DW; Wszolek ZK; Kanekiyo T; Bu G
Mol Neurodegener; 2015 Sep; 10():46. PubMed ID: 26373282
[TBL] [Abstract][Full Text] [Related]
2. Early maturation and distinct tau pathology in induced pluripotent stem cell-derived neurons from patients with MAPT mutations.
Iovino M; Agathou S; González-Rueda A; Del Castillo Velasco-Herrera M; Borroni B; Alberici A; Lynch T; O'Dowd S; Geti I; Gaffney D; Vallier L; Paulsen O; Káradóttir RT; Spillantini MG
Brain; 2015 Nov; 138(Pt 11):3345-59. PubMed ID: 26220942
[TBL] [Abstract][Full Text] [Related]
3. Lrrk2 and chronic inflammation are linked to pallido-ponto-nigral degeneration caused by the N279K tau mutation.
Miklossy J; Qing H; Guo JP; Yu S; Wszolek ZK; Calne D; McGeer EG; McGeer PL
Acta Neuropathol; 2007 Sep; 114(3):243-54. PubMed ID: 17639429
[TBL] [Abstract][Full Text] [Related]
4. Clinical heterogeneity of frontotemporal dementia and Parkinsonism linked to chromosome 17 caused by MAPT N279K mutation in relation to tau positron emission tomography features.
Ikeda A; Shimada H; Nishioka K; Takanashi M; Hayashida A; Li Y; Yoshino H; Funayama M; Ueno Y; Hatano T; Sahara N; Suhara T; Higuchi M; Hattori N
Mov Disord; 2019 Apr; 34(4):568-574. PubMed ID: 30773680
[TBL] [Abstract][Full Text] [Related]
5. Pathogenic implications of mutations in the tau gene in pallido-ponto-nigral degeneration and related neurodegenerative disorders linked to chromosome 17.
Clark LN; Poorkaj P; Wszolek Z; Geschwind DH; Nasreddine ZS; Miller B; Li D; Payami H; Awert F; Markopoulou K; Andreadis A; D'Souza I; Lee VM; Reed L; Trojanowski JQ; Zhukareva V; Bird T; Schellenberg G; Wilhelmsen KC
Proc Natl Acad Sci U S A; 1998 Oct; 95(22):13103-7. PubMed ID: 9789048
[TBL] [Abstract][Full Text] [Related]
6. Induced pluripotent stem cells (iPSCs) derived from a symptomatic carrier of a S305I mutation in the microtubule-associated protein tau (MAPT)-gene causing frontotemporal dementia.
Nimsanor N; Jørring I; Rasmussen MA; Clausen C; Mau-Holzmann UA; Kitiyanant N; Nielsen JE; Nielsen TT; Hyttel P; Holst B; Schmid B
Stem Cell Res; 2016 Nov; 17(3):564-567. PubMed ID: 27789411
[TBL] [Abstract][Full Text] [Related]
7. The tau N279K exon 10 splicing mutation recapitulates frontotemporal dementia and parkinsonism linked to chromosome 17 tauopathy in a mouse model.
Dawson HN; Cantillana V; Chen L; Vitek MP
J Neurosci; 2007 Aug; 27(34):9155-68. PubMed ID: 17715352
[TBL] [Abstract][Full Text] [Related]
8. Mitochondrial hyperpolarization in iPSC-derived neurons from patients of FTDP-17 with 10+16 MAPT mutation leads to oxidative stress and neurodegeneration.
Esteras N; Rohrer JD; Hardy J; Wray S; Abramov AY
Redox Biol; 2017 Aug; 12():410-422. PubMed ID: 28319892
[TBL] [Abstract][Full Text] [Related]
9. Clinical and Pathological Features of FTDP-17 with MAPT p.K298_H299insQ Mutation.
Morino H; Kurashige T; Matsuda Y; Ono M; Sahara N; Miyasaka T; Soeda Y; Shimada H; Yamazaki Y; Takahashi T; Izumi Y; Ito H; Maruyama H; Higuchi M; Arihiro K; Suhara T; Takashima A; Kawakami H
Mov Disord Clin Pract; 2024 Jun; 11(6):720-727. PubMed ID: 38605589
[TBL] [Abstract][Full Text] [Related]
10. Generation of an isogenic, gene-corrected iPSC line from a symptomatic 59-year-old female patient with frontotemporal dementia caused by an R406W mutation in the microtubule associated protein tau (MAPT) gene.
Nimsanor N; Poulsen U; Rasmussen MA; Clausen C; Mau-Holzmann UA; Nielsen JE; Nielsen TT; Hyttel P; Holst B; Schmid B
Stem Cell Res; 2016 Nov; 17(3):576-579. PubMed ID: 27934586
[TBL] [Abstract][Full Text] [Related]
11. Astrocyte pathology in a human neural stem cell model of frontotemporal dementia caused by mutant TAU protein.
Hallmann AL; Araúzo-Bravo MJ; Mavrommatis L; Ehrlich M; Röpke A; Brockhaus J; Missler M; Sterneckert J; Schöler HR; Kuhlmann T; Zaehres H; Hargus G
Sci Rep; 2017 Mar; 7():42991. PubMed ID: 28256506
[TBL] [Abstract][Full Text] [Related]
12. Clinicopathologic heterogeneity in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) due to microtubule-associated protein tau (MAPT) p.P301L mutation, including a patient with globular glial tauopathy.
Tacik P; Sanchez-Contreras M; DeTure M; Murray ME; Rademakers R; Ross OA; Wszolek ZK; Parisi JE; Knopman DS; Petersen RC; Dickson DW
Neuropathol Appl Neurobiol; 2017 Apr; 43(3):200-214. PubMed ID: 27859539
[TBL] [Abstract][Full Text] [Related]
13. A mutation at codon 279 (N279K) in exon 10 of the Tau gene causes a tauopathy with dementia and supranuclear palsy.
Delisle MB; Murrell JR; Richardson R; Trofatter JA; Rascol O; Soulages X; Mohr M; Calvas P; Ghetti B
Acta Neuropathol; 1999 Jul; 98(1):62-77. PubMed ID: 10412802
[TBL] [Abstract][Full Text] [Related]
14. FTDP-17 mutations N279K and S305N in tau produce increased splicing of exon 10.
Hasegawa M; Smith MJ; Iijima M; Tabira T; Goedert M
FEBS Lett; 1999 Jan; 443(2):93-6. PubMed ID: 9989582
[TBL] [Abstract][Full Text] [Related]
15. Generation of a human induced pluripotent stem cell-based model for tauopathies combining three microtubule-associated protein TAU mutations which displays several phenotypes linked to neurodegeneration.
García-León JA; Cabrera-Socorro A; Eggermont K; Swijsen A; Terryn J; Fazal R; Nami F; Ordovás L; Quiles A; Lluis F; Serneels L; Wierda K; Sierksma A; Kreir M; Pestana F; Van Damme P; De Strooper B; Thorrez L; Ebneth A; Verfaillie CM
Alzheimers Dement; 2018 Oct; 14(10):1261-1280. PubMed ID: 30036493
[TBL] [Abstract][Full Text] [Related]
16. FTDP-17 with Pick body-like inclusions associated with a novel tau mutation, p.E372G.
Tacik P; DeTure MA; Carlomagno Y; Lin WL; Murray ME; Baker MC; Josephs KA; Boeve BF; Wszolek ZK; Graff-Radford NR; Parisi JE; Petrucelli L; Rademakers R; Isaacson RS; Heilman KM; Petersen RC; Dickson DW; Kouri N
Brain Pathol; 2017 Sep; 27(5):612-626. PubMed ID: 27529406
[TBL] [Abstract][Full Text] [Related]
17. Dysregulation of Exosome Cargo by Mutant Tau Expressed in Human-induced Pluripotent Stem Cell (iPSC) Neurons Revealed by Proteomics Analyses.
Podvin S; Jones A; Liu Q; Aulston B; Ransom L; Ames J; Shen G; Lietz CB; Jiang Z; O'Donoghue AJ; Winston C; Ikezu T; Rissman RA; Yuan S; Hook V
Mol Cell Proteomics; 2020 Jun; 19(6):1017-1034. PubMed ID: 32295833
[TBL] [Abstract][Full Text] [Related]
18. Segregation of a missense mutation in the microtubule-associated protein tau gene with familial frontotemporal dementia and parkinsonism.
Dumanchin C; Camuzat A; Campion D; Verpillat P; Hannequin D; Dubois B; Saugier-Veber P; Martin C; Penet C; Charbonnier F; Agid Y; Frebourg T; Brice A
Hum Mol Genet; 1998 Oct; 7(11):1825-9. PubMed ID: 9736786
[TBL] [Abstract][Full Text] [Related]
19. Clinical features and disease haplotypes of individuals with the N279K tau gene mutation: a comparison of the pallidopontonigral degeneration kindred and a French family.
Tsuboi Y; Uitti RJ; Delisle MB; Ferreira JJ; Brefel-Courbon C; Rascol O; Ghetti B; Murrell JR; Hutton M; Baker M; Wszolek ZK
Arch Neurol; 2002 Jun; 59(6):943-50. PubMed ID: 12056930
[TBL] [Abstract][Full Text] [Related]
20. Induced pluripotent stem cells (iPSCs) derived from a patient with frontotemporal dementia caused by a P301L mutation in microtubule-associated protein tau (MAPT).
Rasmussen MA; Hjermind LE; Hasholt LF; Waldemar G; Nielsen JE; Clausen C; Hyttel P; Holst B
Stem Cell Res; 2016 Jan; 16(1):70-4. PubMed ID: 27345788
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]